PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9196279-0 1997 Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels. Terfenadine 83-94 potassium voltage-gated channel subfamily A member 5 Homo sapiens 105-110 9196279-2 1997 Upon depolarization to +60 mV, terfenadine, 1 microM and 3 microM, inhibited the hKv1.5 current by 42.4 +/- 6.4% and 69.3 +/- 4.2% (P < 0.01). Terfenadine 31-42 potassium voltage-gated channel subfamily A member 5 Homo sapiens 81-87 7670728-8 1995 Upon depolarization, racemic terfenadine and its enantiomers induced a fast decline of hKv1.5 current towards a reduced steady state current level. Terfenadine 29-40 potassium voltage-gated channel subfamily A member 5 Homo sapiens 87-93 7670728-14 1995 The EC50 for hKv1.5 block by racemic terfenadine was 0.88 microM, while the values for R- and S-terfenadine were 1.19 microM and 1.16 microM, respectively. Terfenadine 37-48 potassium voltage-gated channel subfamily A member 5 Homo sapiens 13-19 8772706-5 1996 We found that HERG was 10 times more sensitive than Kv1.5 to terfenadine block. Terfenadine 61-72 potassium voltage-gated channel subfamily A member 5 Homo sapiens 52-57