PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2892555-9 1987 5 The H1-histamine antagonist terfenadine (60 mg orally) significantly inhibited the wheal and distant flare response to histamine (5 nmol) and NKA, but not that caused by NKB. Terfenadine 30-41 tachykinin precursor 1 Homo sapiens 144-147 1280680-0 1992 Effect of terfenadine on the plasma concentrations of substance P and vasoactive intestinal polypeptide in volunteers. Terfenadine 10-21 tachykinin precursor 1 Homo sapiens 54-65 9349334-9 1997 The mean +/- SEM percentage reduction in flare area for 200 pmol/site of substance P in non-atopics and atopics was 53 +/- 10% and 73 +/- 4% with terfenadine, and 74 +/- 7% and 75 +/- 4% with topical doxepin, respectively. Terfenadine 146-157 tachykinin precursor 1 Homo sapiens 73-84 9349334-11 1997 The inhibitory effects of doxepin were as great as those of terfenadine, and doxepin had a significantly greater effect than terfenadine in inhibiting the weal response to histamine and flare response to substance P in normal volunteers (P < 0.05). Terfenadine 125-136 tachykinin precursor 1 Homo sapiens 204-215 8388006-0 1993 The effect of oral terfenadine on neurokinin-A-induced bronchoconstriction. Terfenadine 19-30 tachykinin precursor 1 Homo sapiens 34-46 7515418-2 1994 During terfenadine treatment, the mean substance P concentrations in nasal secretions from patients allergic to house dust or pollen were significantly decreased to 62 and 39% of the initial values, respectively. Terfenadine 7-18 tachykinin precursor 1 Homo sapiens 39-50 8112439-0 1993 Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects. Terfenadine 15-26 tachykinin precursor 1 Homo sapiens 69-81 1280680-1 1992 The effect of terfenadine on the plasma concentrations of substance P and vasoactive intestinal polypeptide (VIP) was studied in 7 healthy subjects and 8 subjects with the common cold. Terfenadine 14-25 tachykinin precursor 1 Homo sapiens 58-69 1280680-2 1992 Before terfenadine administration, the mean plasma substance P concentration of the subjects with the common cold was significantly higher than that of the healthy subjects. Terfenadine 7-18 tachykinin precursor 1 Homo sapiens 51-62 1280680-3 1992 The increased mean plasma substance P concentration of the subjects with the common cold was decreased after terfenadine administration. Terfenadine 109-120 tachykinin precursor 1 Homo sapiens 26-37