PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12448825-4	2002	Effect of antioxidants on the activation of caspase-3 was determined by feeding a group of diabetic rats diet supplemented with a comprehensive mixture of antioxidants, including Trolox, alpha-tocopherol, N-acetyl cysteine, ascorbic acid, beta-carotene and selenium for 2-14 months, and also under in vitro conditions by incubating isolated retinal capillary cells with antioxidants with wide range of actions.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	179-185	caspase 3	Rattus norvegicus	44-53	
12029627-6	2002	There was release of mitochondrial cytochrome c into the cytosol and activation of caspase 3, which were prevented by cyclosporine, diallylsulfide, and Trolox.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	152-158	caspase 3	Rattus norvegicus	83-92	
10718635-9	2000	The activation of caspase 3 was prevented by diallyldisulfide, by trolox, and by DEVD-fmk.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	66-72	caspase 3	Rattus norvegicus	18-27	
12065696-6	2002	The ROS signal further activated caspase-3, an important effector caspase, which could be inhibited by antioxidants (Trolox or N-acetyl cysteine).	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	117-123	caspase 3	Rattus norvegicus	33-42