PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12448825-4 2002 Effect of antioxidants on the activation of caspase-3 was determined by feeding a group of diabetic rats diet supplemented with a comprehensive mixture of antioxidants, including Trolox, alpha-tocopherol, N-acetyl cysteine, ascorbic acid, beta-carotene and selenium for 2-14 months, and also under in vitro conditions by incubating isolated retinal capillary cells with antioxidants with wide range of actions. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 179-185 caspase 3 Rattus norvegicus 44-53 12029627-6 2002 There was release of mitochondrial cytochrome c into the cytosol and activation of caspase 3, which were prevented by cyclosporine, diallylsulfide, and Trolox. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 152-158 caspase 3 Rattus norvegicus 83-92 10718635-9 2000 The activation of caspase 3 was prevented by diallyldisulfide, by trolox, and by DEVD-fmk. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 66-72 caspase 3 Rattus norvegicus 18-27 12065696-6 2002 The ROS signal further activated caspase-3, an important effector caspase, which could be inhibited by antioxidants (Trolox or N-acetyl cysteine). 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 117-123 caspase 3 Rattus norvegicus 33-42