PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23716696-5 2013 We also show that activated Ypt1 recruits the putative membrane curvature sensor Atg1 to the PAS, bringing it into proximity to its binding partner Atg17. Aminosalicylic Acid 93-96 RAB1A, member RAS oncogene family Homo sapiens 28-32 25800837-4 2015 At the pre-autophagosomal structure (PAS), the localization of the serine/threonine kinase Atg1 was affected in the ypt1-2 mutant. Aminosalicylic Acid 37-40 RAB1A, member RAS oncogene family Homo sapiens 116-120 23716696-7 2013 We propose that Ypt1 regulates Atg9 vesicle tethering by modulating the delivery of Atg1 to the PAS. Aminosalicylic Acid 96-99 RAB1A, member RAS oncogene family Homo sapiens 16-20 22509044-4 2012 Here, we identify Atg11, the preautophagosomal structure (PAS) organizer, as a downstream effector of Ypt1 and show that the Ypt1-Atg11 interaction is required for PAS assembly under normal growth conditions. Aminosalicylic Acid 58-61 RAB1A, member RAS oncogene family Homo sapiens 102-106 22717525-6 2012 Now, a recent report shows that Atg11 is a Trs85-specific effector of the Rab Ypt1, and may act as a classic coiled-coil membrane tether that targets Atg9-containing membranes to the PAS. Aminosalicylic Acid 183-186 RAB1A, member RAS oncogene family Homo sapiens 74-77 22717525-6 2012 Now, a recent report shows that Atg11 is a Trs85-specific effector of the Rab Ypt1, and may act as a classic coiled-coil membrane tether that targets Atg9-containing membranes to the PAS. Aminosalicylic Acid 183-186 RAB1A, member RAS oncogene family Homo sapiens 78-82 22669536-6 2012 In our recent paper, we identify Atg11, a bona fide phagophore assembly site (PAS) component, as a downstream effector of Ypt1. Aminosalicylic Acid 78-81 RAB1A, member RAS oncogene family Homo sapiens 122-126 22669536-7 2012 Moreover, we show that three components of a GTPase module--the Ypt1 activator, Trs85-containing TRAPP complex, Ypt1, and the Atg11 effector--interact on the PAS and are required for PAS formation during selective autophagy. Aminosalicylic Acid 158-161 RAB1A, member RAS oncogene family Homo sapiens 64-68 22669536-7 2012 Moreover, we show that three components of a GTPase module--the Ypt1 activator, Trs85-containing TRAPP complex, Ypt1, and the Atg11 effector--interact on the PAS and are required for PAS formation during selective autophagy. Aminosalicylic Acid 158-161 RAB1A, member RAS oncogene family Homo sapiens 112-116 22669536-7 2012 Moreover, we show that three components of a GTPase module--the Ypt1 activator, Trs85-containing TRAPP complex, Ypt1, and the Atg11 effector--interact on the PAS and are required for PAS formation during selective autophagy. Aminosalicylic Acid 183-186 RAB1A, member RAS oncogene family Homo sapiens 64-68 22669536-7 2012 Moreover, we show that three components of a GTPase module--the Ypt1 activator, Trs85-containing TRAPP complex, Ypt1, and the Atg11 effector--interact on the PAS and are required for PAS formation during selective autophagy. Aminosalicylic Acid 183-186 RAB1A, member RAS oncogene family Homo sapiens 112-116 22509044-4 2012 Here, we identify Atg11, the preautophagosomal structure (PAS) organizer, as a downstream effector of Ypt1 and show that the Ypt1-Atg11 interaction is required for PAS assembly under normal growth conditions. Aminosalicylic Acid 58-61 RAB1A, member RAS oncogene family Homo sapiens 125-129 22509044-6 2012 Finally, we show that Ypt1 and Trs85 interact on Atg9-containing membranes, which serve as a source for the membrane component of the PAS. Aminosalicylic Acid 134-137 RAB1A, member RAS oncogene family Homo sapiens 22-26 20375281-6 2010 The Trs85 subunit of the TRAPPIII complex directs this Ypt1 GEF to the phagophore assembly site (PAS) that is involved in autophagosome formation. Aminosalicylic Acid 97-100 RAB1A, member RAS oncogene family Homo sapiens 55-59 20375281-7 2010 Consistent with the observation that a Ypt1 GEF is directed to the PAS, we find that Ypt1 is essential for autophagy. Aminosalicylic Acid 67-70 RAB1A, member RAS oncogene family Homo sapiens 39-43