PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23321721-7	2013	In yeast, membrane binding by Atg5 is not required for its recruitment to the phagophore assembly site (PAS) but is essential for efficient promotion of autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway at a stage preceding Atg8 lipidation and autophagosome closure.	Aminosalicylic Acid	104-107	Atg5p	Saccharomyces cerevisiae S288C	30-34	
30810528-2	2019	Previous studies in yeast revealed that the autophagy-related E3 complex Atg12-Atg5-Atg16 is recruited to the PAS via Atg16 interaction with Atg21, which binds phosphatidylinositol 3-phosphate (PI3P) produced at the PAS, to stimulate conjugation of the ubiquitin-like protein Atg8 to phosphatidylethanolamine.	Aminosalicylic Acid	110-113	Atg5p	Saccharomyces cerevisiae S288C	79-83	
30810528-2	2019	Previous studies in yeast revealed that the autophagy-related E3 complex Atg12-Atg5-Atg16 is recruited to the PAS via Atg16 interaction with Atg21, which binds phosphatidylinositol 3-phosphate (PI3P) produced at the PAS, to stimulate conjugation of the ubiquitin-like protein Atg8 to phosphatidylethanolamine.	Aminosalicylic Acid	216-219	Atg5p	Saccharomyces cerevisiae S288C	79-83	
30810528-3	2019	Here, we discover a novel mechanism for the PAS targeting of Atg12-Atg5-Atg16, which is mediated by the interaction of Atg12 with the Atg1 kinase complex that serves as a scaffold for PAS organization.	Aminosalicylic Acid	44-47	Atg5p	Saccharomyces cerevisiae S288C	67-71	
25500271-6	2015	It is involved in a step downstream of PAS (phagophore assembly site) scaffold assembly, and upstream of the recruitment of Atg1, Atg14, Atg5 and Atg8.	Aminosalicylic Acid	39-42	Atg5p	Saccharomyces cerevisiae S288C	137-141	
30810528-3	2019	Here, we discover a novel mechanism for the PAS targeting of Atg12-Atg5-Atg16, which is mediated by the interaction of Atg12 with the Atg1 kinase complex that serves as a scaffold for PAS organization.	Aminosalicylic Acid	184-187	Atg5p	Saccharomyces cerevisiae S288C	67-71	
30810528-4	2019	While autophagy is partially defective without one of these mechanisms, cells lacking both completely lose the PAS localization of Atg12-Atg5-Atg16 and show no autophagic activity.	Aminosalicylic Acid	111-114	Atg5p	Saccharomyces cerevisiae S288C	137-141	
30810528-5	2019	As with the PI3P-dependent mechanism, Atg12-Atg5-Atg16 recruited via the Atg12-dependent mechanism stimulates Atg8 lipidation, but also has the specific function of facilitating PAS scaffold assembly.	Aminosalicylic Acid	178-181	Atg5p	Saccharomyces cerevisiae S288C	44-48