PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30488170-0 2019 Ethanol Exacerbates Manganese-Induced Neurobehavioral Deficits, Striatal Oxidative Stress, and Apoptosis Via Regulation of p53, Caspase-3, and Bax/Bcl-2 Ratio-Dependent Pathway. Manganese 20-29 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 123-126 25791630-0 2015 Involvement of dysregulated Wip1 in manganese-induced p53 signaling and neuronal apoptosis. Manganese 36-45 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 54-57 30284675-0 2019 Ethanol via Regulation of NF-kappaB/p53 Signaling Pathway Increases Manganese-Induced Inflammation and Apoptosis in Hypothalamus of Rats. Manganese 68-77 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 36-39 30844427-0 2019 Ethanol increases manganese-Induced spatial learning and memory deficits via oxidative/nitrosative stress induced p53 dependent/independent hippocampal apoptosis. Manganese 18-27 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 114-117 17623882-11 2007 To investigate whether there are any apoptotic gene expression changes during apoptosis, we examined the expression level of Bcl-2, Bax, and P53 mRNAs after treatment with 500 microM of manganese for 48 h. The Bcl-2 mRNA expression decreased while the expression of Bax as well as P53 mRNAs increased. Manganese 186-195 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 141-144 16293243-8 2005 These results suggested that the activation of JNK and the upregulation of c-Jun, p53 and p21(WAF1/CIP1) were involved in the apoptosis of hepatocytes induced by partial hepatectomy with manganese. Manganese 187-196 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 82-85 25448048-0 2014 Pivotal roles of p53 transcription-dependent and -independent pathways in manganese-induced mitochondrial dysfunction and neuronal apoptosis. Manganese 74-83 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 17-20