PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2542339-3	1989	The polylysine-dependent insulin stimulation of protein kinase activity required the presence of both magnesium and manganese but at relatively low divalent metal ion concentrations (0.1 mM) compared to the typical 2-10 mM Mg/Mn used in the standard in vitro kinase assays.	Manganese	116-125	insulin	Homo sapiens	25-32	
34671948-7	2021	This article will review the research progress of MNs in insulin transdermal delivery, including hollow MNs, dissolving MNs, hydrogel MNs, and glucose-responsive MN patches, in which insulin dosage can be strictly controlled.	Manganese	50-53	insulin	Homo sapiens	57-64	
34671948-7	2021	This article will review the research progress of MNs in insulin transdermal delivery, including hollow MNs, dissolving MNs, hydrogel MNs, and glucose-responsive MN patches, in which insulin dosage can be strictly controlled.	Manganese	50-53	insulin	Homo sapiens	183-190	
35310304-0	2022	Manganese-induced parkinsonism responsive to intranasal insulin: A case report.	Manganese	0-9	insulin	Homo sapiens	56-63	
26849622-12	2016	Fluorescence-spectrophotometry and manganese quench experiments indicated that the increased TRPC6-expression after insulin administration was accompanied by an elevated transplasmamembrane cation influx.	Manganese	35-44	insulin	Homo sapiens	116-123	
32736831-10	2020	RESULTS: Models obtained from the resulting INQs of manganese as a continuous variable in relationship with waist circumference represented a significant association after multivariate adjustment of age, sex, height, fat free mass, weight, body mass index, marital status, TF, fasting blood sugar, low-density lipoproteins, high-density lipoproteins, total cholesterol, insulin resistance, and total energy intake (odds ratio = 0.24, CI = 0.07-0.79).	Manganese	52-61	insulin	Homo sapiens	370-377	
26729523-10	2016	Overall, it can be inferred that the application of MNs can significantly enhance insulin permeation and may be an efficient alternative for injectable insulin therapy in humans.	Manganese	52-55	insulin	Homo sapiens	82-89	
28712229-0	2016	Insulin Sensitivity To Trace Metals (Chromium, Manganese) In Type 2 Diabetic Patients And Non Diabetic Individuals.	Manganese	47-56	insulin	Homo sapiens	0-7	
32540546-0	2020	Sex-specific associations of blood and urinary manganese levels with glucose levels, insulin resistance and kidney function in US adults: National health and nutrition examination survey 2011-2016.	Manganese	47-56	insulin	Homo sapiens	85-92	
32507191-3	2020	After application into human abdominal skin in vitro, the MNs dissolved within 2 h releasing up to 87% of insulin.	Manganese	58-61	insulin	Homo sapiens	106-113	
23322284-2	2013	Pathophysiology in relation with the essential elements including copper, magnesium, zinc, manganese, chromium, and calcium has been reported in women with insulin resistance.	Manganese	91-100	insulin	Homo sapiens	156-163	
22072339-0	2011	[An inadequate intake of manganese may favour insulin resistance in girls].	Manganese	25-34	insulin	Homo sapiens	46-53	
22072339-1	2011	AIM: to study the relationship between an adequate manganese (Mn) intake and glucose, insulin levels and insulin resistance among healthy children from Madrid (Spain).	Manganese	51-60	insulin	Homo sapiens	105-112