PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22534978-0	2012	Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells.	Manganese	59-68	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	9-13	
29927450-1	2018	ZIP8 is a recently identified membrane transporter which facilitates uptake of many substrates including both essential and toxic divalent metals (e.g. zinc, manganese, iron, cadmium) and inorganic selenium.	Manganese	158-167	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	0-4	
28481222-0	2017	Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.	Manganese	45-54	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	30-34	
28481222-0	2017	Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.	Manganese	71-80	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	30-34	
28481222-1	2017	Genetic variants at the solute carrier family 39 member 8 (SLC39A8) gene locus are associated with the regulation of whole-blood manganese (Mn) and multiple physiological traits.	Manganese	129-138	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	59-66	
24345748-10	2014	In summary, at the daily oral Cd exposures chosen for this study, 5 versus 2 Slc39a8 gene copies result in no differences in Cd toxicity but do cause differences in tissue-specific content of Cd, zinc, manganese, calcium, iron, and copper.	Manganese	202-211	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	77-84	
24989470-5	2014	ZIP8 is involved in the transport of zinc, manganese, and cadmium from the extracellular space or intracellular compartments into the cytosol.	Manganese	43-52	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	0-4	
33139556-0	2020	A missense variant in SLC39A8 confers risk for Crohn"s disease by disrupting manganese homeostasis and intestinal barrier integrity.	Manganese	77-86	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	22-29	
16638970-6	2006	The Km for Cd2+ uptake was 0.62 microM, and the Km for Mn2+ uptake was 2.2 microM; thus, manganese is probably the physiological substrate for ZIP8.	Manganese	89-98	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	143-147	
21172401-9	2011	These results suggest that the suppressed expression of ZIP8 and DMT1, which are known to have affinities for both cadmium and manganese, may be responsible for the reduction in the uptake, and consequently the cytotoxicity, of cadmium and manganese in A+70 and B+70 cells.	Manganese	127-136	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	56-60	
21172401-9	2011	These results suggest that the suppressed expression of ZIP8 and DMT1, which are known to have affinities for both cadmium and manganese, may be responsible for the reduction in the uptake, and consequently the cytotoxicity, of cadmium and manganese in A+70 and B+70 cells.	Manganese	240-249	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	56-60