PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15136298-3	2004	We therefore studied the effect of a new thiol antioxidant compound, Nacystelyn (NAL), on IL-8 regulation in a human macrophage-derived cell line (THP-1).	N-acetylcysteine lysinate	69-79	C-X-C motif chemokine ligand 8	Homo sapiens	90-94	
15136298-3	2004	We therefore studied the effect of a new thiol antioxidant compound, Nacystelyn (NAL), on IL-8 regulation in a human macrophage-derived cell line (THP-1).	N-acetylcysteine lysinate	81-84	C-X-C motif chemokine ligand 8	Homo sapiens	90-94	
31729901-7	2020	Moreover, p38/MAPK inhibitor SB203580 and NF-kappaB inhibitor BAY11-7082 could block the IL-8 up-regulated by X-rays but JNK inhibitor SP600125, ERK inhibitor U0126, ROS Scavenger NAC could not inhibit this phenomenon.Conclusions: X-rays could induce IL-8 production in lung cancer cells, which may be related to the activation of p38/MAPK and NF-kappaB signaling pathway, providing a new point for elucidating the mechanism of radiation pneumonitis.	N-acetylcysteine lysinate	180-183	C-X-C motif chemokine ligand 8	Homo sapiens	89-93	
11958950-0	2002	Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells.	N-acetylcysteine lysinate	0-10	C-X-C motif chemokine ligand 8	Homo sapiens	37-50	
11958950-3	2002	NAL (5 mM) enhanced intracellular glutathione (GSH) after 4 h and abolished H(2)O(2)-induced IL-8 release from A549 cells.	N-acetylcysteine lysinate	0-3	C-X-C motif chemokine ligand 8	Homo sapiens	93-97	
11958950-5	2002	NAL also abolished the transcriptional activation of IL-8 in an IL-8-chloramphenicol acetyl transferase (CAT) reporter system, transfected into A549 cells.	N-acetylcysteine lysinate	0-3	C-X-C motif chemokine ligand 8	Homo sapiens	53-57	
11958950-5	2002	NAL also abolished the transcriptional activation of IL-8 in an IL-8-chloramphenicol acetyl transferase (CAT) reporter system, transfected into A549 cells.	N-acetylcysteine lysinate	0-3	C-X-C motif chemokine ligand 8	Homo sapiens	64-68