PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28748912-7	2017	Kinetic analyses were performed using a luminescent ADP detection assay by varying the concentrations of a peptide substrate, and the results showed that the mutations I78C and I78W decreased CK2alpha activity, whereas V31R, K75E, I82C and P109C increased CK2alpha activity.	Adenosine Diphosphate	52-55	casein kinase 2 alpha 2	Homo sapiens	192-200	
11439109-3	2001	At variance with serine-autophosphorylation, tyrosine-autophosphorylation of CK2alpha is reversed by ADP and GDP and is counteracted by the beta-subunit and by a peptide reproducing the activation loop of CK2alpha/alpha" (amino acids 175-201).	Adenosine Diphosphate	101-104	casein kinase 2 alpha 2	Homo sapiens	77-85	
24531484-0	2014	The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.	Adenosine Diphosphate	144-147	casein kinase 2 alpha 2	Homo sapiens	82-90	
24531484-9	2014	This may suggest a clue to a possible ADP/GDP-release pathway, because the NE1 atom of the Trp in the `DWG motif" of CK2alpha forms a hydrogen bond to the O atom of Leu212, which seems to make ADP release by means of the `DFG-in flip to DFG-out" model found in most eukaryotic protein kinases impossible.	Adenosine Diphosphate	38-41	casein kinase 2 alpha 2	Homo sapiens	117-125	
24531484-9	2014	This may suggest a clue to a possible ADP/GDP-release pathway, because the NE1 atom of the Trp in the `DWG motif" of CK2alpha forms a hydrogen bond to the O atom of Leu212, which seems to make ADP release by means of the `DFG-in flip to DFG-out" model found in most eukaryotic protein kinases impossible.	Adenosine Diphosphate	193-196	casein kinase 2 alpha 2	Homo sapiens	117-125