PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
4015695-1	1985	Diltiazem and verapamil were found to be inhibitors of the cytochrome P-450-dependent biotransformation of drugs.	Diltiazem	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	59-75	
9223567-1	1997	The antihypertensive agent diltiazem (DTZ) impairs hepatic drug metabolism by inhibition of cytochrome P450 (CYP).	Diltiazem	27-36	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	92-107	
9223567-1	1997	The antihypertensive agent diltiazem (DTZ) impairs hepatic drug metabolism by inhibition of cytochrome P450 (CYP).	Diltiazem	27-36	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	109-112	
9223567-1	1997	The antihypertensive agent diltiazem (DTZ) impairs hepatic drug metabolism by inhibition of cytochrome P450 (CYP).	Diltiazem	38-41	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	92-107	
9223567-1	1997	The antihypertensive agent diltiazem (DTZ) impairs hepatic drug metabolism by inhibition of cytochrome P450 (CYP).	Diltiazem	38-41	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	109-112	
9223567-3	1997	Thus, DTZ metabolites may contribute to CYP inhibition.	Diltiazem	6-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	40-43	
9223567-4	1997	This study assessed the role of human CYPs in microsomal DTZ oxidation and the capacity of DTZ metabolites to inhibit specific CYP activities.	Diltiazem	57-60	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	38-41