PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28214691-1 2017 Diltiazem has been used for post-transplant hypertension, but the mechanism underlying its protective effect of endothelial cells against angiotensin II (Ang II) - induced impairment remains unclear. Diltiazem 0-9 angiotensinogen Homo sapiens 138-152 28214691-1 2017 Diltiazem has been used for post-transplant hypertension, but the mechanism underlying its protective effect of endothelial cells against angiotensin II (Ang II) - induced impairment remains unclear. Diltiazem 0-9 angiotensinogen Homo sapiens 154-160 28214691-5 2017 Treatment with 10-6M Ang II for 24h induced a significant decrease in the mRNA and protein levels of eNOS, which was significantly increased by the pre-incubated with diltiazem (10-6M). Diltiazem 167-176 angiotensinogen Homo sapiens 21-27 28214691-6 2017 Treatment with 10-6M Ang II for 24h induced a significant increase in the mRNA and protein levels of p47 phox subunit of NADHP oxidase, which was significantly decreased by the pre-incubated with diltiazem. Diltiazem 196-205 angiotensinogen Homo sapiens 21-27 28214691-8 2017 The results reveal that diltiazem inhibits the Ang II - induced oxidative stress in HUVECs, which may be partly mediated by GHSR1a. Diltiazem 24-33 angiotensinogen Homo sapiens 47-53 1318127-4 1992 In the present study, the effect of nifedipine and diltiazem on AII- and PDGF-BB-induced vascular smooth muscle cell proliferation was examined. Diltiazem 51-60 angiotensinogen Homo sapiens 64-67 11240977-8 2001 The venodilation caused by diltiazem was also attenuated by angiotensin II, but this attenuating effect was smaller compared with that caused by nitroglycerin. Diltiazem 27-36 angiotensinogen Homo sapiens 60-74 11240977-9 2001 CONCLUSIONS: These findings suggest that an enhanced angiotensin II level might attenuate the venodilation caused by nitroglycerin and diltiazem, and pretreatment with losartan might decrease the attenuating effect of angiotensin II. Diltiazem 135-144 angiotensinogen Homo sapiens 53-67 1490588-6 1992 The vasorelaxant effect of ANP on AT II-induced contraction was significantly increased in Ca(2+)-free medium containing 3 mM ethylene glycol bis(beta-aminoethyl ether) N,N,N",N"-tetraacetic acid (EGTA-Ringer) or by pretreatment with the calcium antagonist, diltiazem (DIL). Diltiazem 258-267 angiotensinogen Homo sapiens 34-39 1490588-6 1992 The vasorelaxant effect of ANP on AT II-induced contraction was significantly increased in Ca(2+)-free medium containing 3 mM ethylene glycol bis(beta-aminoethyl ether) N,N,N",N"-tetraacetic acid (EGTA-Ringer) or by pretreatment with the calcium antagonist, diltiazem (DIL). Diltiazem 269-272 angiotensinogen Homo sapiens 34-39 1318127-7 1992 Both AII- and PDGF-BB-induced DNA synthesis was significantly blunted by diltiazem and nifedipine in a concentration of 10 microM, while no significant influence was seen with concentrations from 10 nM up to 1 microM. Diltiazem 73-82 angiotensinogen Homo sapiens 5-8 2933950-4 1985 Diltiazem may increase glomerular filtration rate via attenuation of the intrarenal effects of angiotensin II or norepinephrine. Diltiazem 0-9 angiotensinogen Homo sapiens 95-109 1942082-3 1991 The inotropic effect of AII was markedly inhibited by 1 microM saralasin or 1 microM diltiazem. Diltiazem 85-94 angiotensinogen Homo sapiens 24-27 2891847-4 1988 Diltiazem also inhibited mesenteric vasoconstrictor responses to angiotensin II, vasopressin, prostaglandin F2 alpha and KCl. Diltiazem 0-9 angiotensinogen Homo sapiens 65-79 3623678-9 1987 The results suggest that in normal subjects increased DBP responses to ANG II, induced by an increase in sodium intake, are partially mediated by increased extracellular to intracellular calcium movements, since they are blocked by the structurally different calcium channel blocking drugs nifedipine and diltiazem. Diltiazem 305-314 angiotensinogen Homo sapiens 71-77 3544786-4 1987 Diltiazem may increase glomerular filtration rate via attenuation of the intrarenal effects of angiotensin II or norepinephrine. Diltiazem 0-9 angiotensinogen Homo sapiens 95-109 3760114-6 1986 During the high sodium diet (200 meq Na/day), only diltiazem decreased AII sensitivity, and the reduction was less (P less than 0.05) than that during the low sodium diet. Diltiazem 51-60 angiotensinogen Homo sapiens 71-74 3760114-10 1986 The results suggest that in normal subjects, increased plasma aldosterone responses to AII induced by reduction in sodium intake are partially mediated by increased extracellular to intracellular calcium movements, since they are blocked by the structurally different calcium channel-blocking drugs nifedipine and diltiazem. Diltiazem 314-323 angiotensinogen Homo sapiens 87-90 6376141-0 1984 Diltiazem and verapamil: functional antagonism of exogenous noradrenaline and angiotensin II in man. Diltiazem 0-9 angiotensinogen Homo sapiens 60-92 6376141-5 1984 During the administration of diltiazem and verapamil, the increase in blood pressure in response to the infusion of NA and angiotensin II was attenuated; the increase in diastolic pressure was mainly affected. Diltiazem 29-38 angiotensinogen Homo sapiens 123-137 7262036-1 1980 The effect of diltiazem hydrochloride (DTZ), a calcium-antagonist, on pressor and steroidogenic action of angiotensin II (AII), angiotensin III (AIII) and norepinephrine (NE) was studied in 5 normal men. Diltiazem 14-37 angiotensinogen Homo sapiens 106-120