PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12709682-6	2003	At the end of CPB, the mean IL-6 level in the control group was significantly higher than in the diltiazem group (p=0.015), and at 3 hours after CPB the difference was even greater (p=0.002).	Diltiazem	97-106	interleukin 6	Homo sapiens	28-32	
12709682-8	2003	CONCLUSIONS: Diltiazem inhibits the release of the pro-inflammatory cytokine IL-6, which is strong evidence for its anti-inflammatory effect.	Diltiazem	13-22	interleukin 6	Homo sapiens	77-81	
9625031-6	1998	RESULTS: An interesting effect on proinflammatory monokines was observed: in this study, we demonstrate that the calcium antagonist diltiazem enhances interleukin-1beta and slightly reduces interleukin-6 production in MLC, but it has no effect on tumor necrosis factor-alpha levels.	Diltiazem	132-141	interleukin 6	Homo sapiens	190-203	
10226093-2	1999	We investigated the underlying molecular mechanism responsible for IL-6 induction in response to the CCB amlodipine, diltiazem, and verapamil in primary human vascular smooth muscle cells (VSMC).	Diltiazem	117-126	interleukin 6	Homo sapiens	67-71	
7538432-8	1994	APP expression in H-35 and HepG2 cells, stimulated by interleukin 1 (IL-1), IL-6, and dexamethasone, was inhibited by diltiazem or verapamil but not SOD.	Diltiazem	118-127	interleukin 6	Homo sapiens	76-80	
8920958-4	1996	The maximal IL-6-induced increase in IGFBP-1 was comparable to that observed with dexamethasone, and this increase was attenuated by diltiazem or dantrolene, both of which are known to reduce the cytosolic Ca2+ concentration.	Diltiazem	133-142	interleukin 6	Homo sapiens	12-16	
1871801-6	1991	Both, CsA and high doses of diltiazem caused an increase of IL-6 mRNA.	Diltiazem	28-37	interleukin 6	Homo sapiens	60-64	
3006091-2	1986	The specific binding and internalization of human 125I-labeled LDL are dose-dependently increased in HSF by CA of the verapamil series (verapamil, anipamil, gallopamil, ronipamil, and diltiazem), but neither by CA of the dihydropyridine series (nifedipine, nitrendipine) nor by flunarizine.	Diltiazem	184-193	interleukin 6	Homo sapiens	101-104