PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28925123-8 2016 Compared with the model group, the degree of myocardial infarct, MDA concentration in cardiac tissue and the levels of TnI in serum significantly decreased in the diltiazem group and flavonoids of Epimedium low and high doses groups (P<0.05 or P<0.01); flavonoids of Epimedium low and high doses groups and the diltiazem group also showed improvements in myocardium structure under ischemia/reperfusion injury. Diltiazem 163-172 troponin I3, cardiac type Rattus norvegicus 119-122 25989107-9 2015 CA4P injection also significantly increased the cardiac troponin I level in hypertensive rats though pretreatment with diltiazem effectively blocked troponin I increase after CA4P administration. Diltiazem 119-128 troponin I3, cardiac type Rattus norvegicus 48-66 18423659-7 2008 In comparison RCM cTnI mutants in the helix-4/C-terminal region demonstrated a) hyper-sensitivity to Ca(2+) under loaded conditions, b) slowed myocyte mechanical relaxation and Ca(2+) transient decay, c) frequency-dependent Ca(2+)-independent diastolic tone, d) heightened myofilament incorporation and e) irreversible cellular contractile defects with acute diltiazem administration. Diltiazem 359-368 troponin I3, cardiac type Rattus norvegicus 18-22