PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28006832-4 2017 We have recently shown that WS 1442 protects against this dysfunction by a dual mechanism: it both promotes endothelial barrier integrity by activation of a barrier-enhancing pathway (cortactin activation) and inhibits endothelial hyperpermeability by blocking a barrier disruptive pathway (calcium signaling). Tungsten 28-30 cortactin Homo sapiens 184-193