PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8865140-4 1996 The effects on HDL are modified to different degrees by progestins, depending on the androgenic properties of the latter: the "sex steroid sensitive" HDL2 subfraction is decreased by nortestosterone derived progestins with androgenic activity. Steroids 131-138 junctophilin 3 Homo sapiens 150-154 2082909-2 1990 In general, steroids with oestrogenic activity increase plasma levels of HDL, especially HDL2, and reduce levels of LDL. Steroids 12-20 junctophilin 3 Homo sapiens 89-93 2105436-3 1990 During the period of steroid administration, there was a slight reduction in total serum cholesterol, with a marked cholesterol decrease in the high-density lipoprotein (HDL) subfractions HDL2 and HDL3, and a significant reduction in the HDL2 cholesterol/HDL3 cholesterol ratio; the percentage of serum cholesterol transported by low-density lipoproteins (LDL) increased significantly. Steroids 21-28 junctophilin 3 Homo sapiens 188-192 2105436-3 1990 During the period of steroid administration, there was a slight reduction in total serum cholesterol, with a marked cholesterol decrease in the high-density lipoprotein (HDL) subfractions HDL2 and HDL3, and a significant reduction in the HDL2 cholesterol/HDL3 cholesterol ratio; the percentage of serum cholesterol transported by low-density lipoproteins (LDL) increased significantly. Steroids 21-28 junctophilin 3 Homo sapiens 238-242 2486441-2 1990 Exogenous sex steroids appear to influence lipoproteins in a manner that is a caricature of the effects of endogenous sex steroids: Estrogens raise HDL (selectively HDL2) and lower LDL; Androgens lower HDL (selectively HDL2), while raising LDL. Steroids 14-22 junctophilin 3 Homo sapiens 148-151 2486441-2 1990 Exogenous sex steroids appear to influence lipoproteins in a manner that is a caricature of the effects of endogenous sex steroids: Estrogens raise HDL (selectively HDL2) and lower LDL; Androgens lower HDL (selectively HDL2), while raising LDL. Steroids 14-22 junctophilin 3 Homo sapiens 165-169 2486441-2 1990 Exogenous sex steroids appear to influence lipoproteins in a manner that is a caricature of the effects of endogenous sex steroids: Estrogens raise HDL (selectively HDL2) and lower LDL; Androgens lower HDL (selectively HDL2), while raising LDL. Steroids 14-22 junctophilin 3 Homo sapiens 165-168 2486441-2 1990 Exogenous sex steroids appear to influence lipoproteins in a manner that is a caricature of the effects of endogenous sex steroids: Estrogens raise HDL (selectively HDL2) and lower LDL; Androgens lower HDL (selectively HDL2), while raising LDL. Steroids 14-22 junctophilin 3 Homo sapiens 219-223 2486441-2 1990 Exogenous sex steroids appear to influence lipoproteins in a manner that is a caricature of the effects of endogenous sex steroids: Estrogens raise HDL (selectively HDL2) and lower LDL; Androgens lower HDL (selectively HDL2), while raising LDL. Steroids 122-130 junctophilin 3 Homo sapiens 148-151 2486441-7 1990 Exogenous sex steroids appear to alter HDL levels predominantly via modulation of HDL catabolism; Estrogens retard HDL catabolism (33) (and may also increase apo A-I synthesis and HDL production); Androgens accelerate HDL catabolism (30). Steroids 14-22 junctophilin 3 Homo sapiens 39-42 2486441-7 1990 Exogenous sex steroids appear to alter HDL levels predominantly via modulation of HDL catabolism; Estrogens retard HDL catabolism (33) (and may also increase apo A-I synthesis and HDL production); Androgens accelerate HDL catabolism (30). Steroids 14-22 junctophilin 3 Homo sapiens 82-85 2486441-7 1990 Exogenous sex steroids appear to alter HDL levels predominantly via modulation of HDL catabolism; Estrogens retard HDL catabolism (33) (and may also increase apo A-I synthesis and HDL production); Androgens accelerate HDL catabolism (30). Steroids 14-22 junctophilin 3 Homo sapiens 82-85 2486441-7 1990 Exogenous sex steroids appear to alter HDL levels predominantly via modulation of HDL catabolism; Estrogens retard HDL catabolism (33) (and may also increase apo A-I synthesis and HDL production); Androgens accelerate HDL catabolism (30). Steroids 14-22 junctophilin 3 Homo sapiens 82-85 2486441-9 1990 Modulation of HDL (and possibly LDL) metabolism by sex steroids may be mediated by alterations in hepatic triglyceride lipase (HTGL) activity. Steroids 55-63 junctophilin 3 Homo sapiens 14-17 2708728-9 1989 At the peak of steroid administration significant changes were observed in LDL (22% increase), HDL (63% decrease), HDL-2 (86% decrease), HDL-3 (54% decrease), and TC/HDL (85% increase). Steroids 15-22 junctophilin 3 Homo sapiens 115-120 3657514-1 1987 Administration of the androgenic anabolic steroid, stanozolol, is associated with decreased high density lipoprotein (HDL) cholesterol (primarily due to decreased HDL2 cholesterol) and increased levels of postheparin plasma hepatic triglyceride lipase (HTGL) activity. Steroids 42-49 junctophilin 3 Homo sapiens 163-167 3746133-9 1986 Contraceptive steroids also caused a decrease in the HDL2/HDL3 cholesterol ratio (P less than 0.05), implying impaired peripheral lipoprotein triglyceride hydrolysis and/or increased HDL2 clearance by hepatic triglyceride lipase. Steroids 14-22 junctophilin 3 Homo sapiens 53-57 3746133-9 1986 Contraceptive steroids also caused a decrease in the HDL2/HDL3 cholesterol ratio (P less than 0.05), implying impaired peripheral lipoprotein triglyceride hydrolysis and/or increased HDL2 clearance by hepatic triglyceride lipase. Steroids 14-22 junctophilin 3 Homo sapiens 183-187 7076794-8 1982 The results are compatible with the hypothesis that the effects of sex steroids on plasma HDL (HDL2) are mediated by changes in hepatic lipase activity. Steroids 71-79 junctophilin 3 Homo sapiens 90-93 7076794-8 1982 The results are compatible with the hypothesis that the effects of sex steroids on plasma HDL (HDL2) are mediated by changes in hepatic lipase activity. Steroids 71-79 junctophilin 3 Homo sapiens 95-99 6460509-5 1981 The results suggest, first, that the decrease of HDL cholesterol observed during treatment with progestins is related to the androgenic activity of the steroid used, and, second, that the change in HDL (HDL2) is caused by androgen-induced increase of hepatic lipase activity. Steroids 152-159 junctophilin 3 Homo sapiens 203-207