PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24793994-1 2014 During the first two trimesters of intrauterine life, fetal sex steroid production is driven by maternal human chorionic gonadotropin (hCG). Steroids 64-71 hypertrichosis 2 (generalised, congenital) Homo sapiens 135-138 29120657-6 2017 The users mainly well informed from internet use for amelioration of the symptoms injections of human choriogonadotropin (hCG), selective estrogen receptor modulators (SERM) or aromatase inhibitors.Key words: anabolic steroids - doping - hypogonadotropic hypogonadism - side effects. Steroids 218-226 hypertrichosis 2 (generalised, congenital) Homo sapiens 122-125 26690776-5 2016 Accordingly, CREB phosphorylation and steroid production is increased under hCG and FSH co-treatment. Steroids 38-45 hypertrichosis 2 (generalised, congenital) Homo sapiens 76-79 24297796-1 2014 CONTEXT: The role of human chorionic gonadotropin (hCG) supplementation on the intrafollicular steroid milieu has been studied. Steroids 95-102 hypertrichosis 2 (generalised, congenital) Homo sapiens 51-54 23925891-6 2014 The hCG of all the test compounds was most effective in both the induction of GVBD% and steroid production. Steroids 88-95 hypertrichosis 2 (generalised, congenital) Homo sapiens 4-7 22427666-4 2012 Human chorionic gonadotropin (hCG) induces de novo synthesis of STAR, a process shown to parallel maximal steroid production. Steroids 106-113 hypertrichosis 2 (generalised, congenital) Homo sapiens 30-33 18325003-8 2008 Based on these findings, we conclude that hCG stimulation can suppress hepatic CYP2E1 and CYP2A activities, probably through an increase in the levels of testicular steroids. Steroids 165-173 hypertrichosis 2 (generalised, congenital) Homo sapiens 42-45 21046485-9 2010 Follicles exposed to a combination of 25 mIU/ml FSH and 3 mIU/ml hCG and elevated aromatizable androgens altered the steroid production profile, affected the follicular development and impaired oocyte meiotic competence. Steroids 117-124 hypertrichosis 2 (generalised, congenital) Homo sapiens 65-68 20463053-3 2010 In the present study, we address the molecular and cellular mechanisms underlying the effects of MEHP on basal and human chorionic gonadotropin (hCG)-stimulated steroid production by MA-10 Leydig cells, using a systems biology approach. Steroids 161-168 hypertrichosis 2 (generalised, congenital) Homo sapiens 145-148 20463053-4 2010 MEHP induced dose-dependent decreases in hCG-stimulated steroid formation. Steroids 56-63 hypertrichosis 2 (generalised, congenital) Homo sapiens 41-44 20463053-9 2010 The MEHP-induced decreases in hCG-stimulated steroid formation were paralleled by increases in reactive oxygen species generation, with the latter mediated by the Cyp1a1 gene and its network. Steroids 45-52 hypertrichosis 2 (generalised, congenital) Homo sapiens 30-33 16928894-5 2007 Based on these findings, we propose that prolonged HA deficiency in HDC KO mice affects various aspects of Leydig cell physiology, most importantly the response to hCG, providing definite evidence that HA plays a role as direct modulator of Leydig cell function and steroid synthesis in the testis. Steroids 266-273 hypertrichosis 2 (generalised, congenital) Homo sapiens 164-167 17363138-1 2007 Adrenal cortex hyperfunction may occasionally be due to stimulation of steroid hormone production by LH/hCG. Steroids 71-86 hypertrichosis 2 (generalised, congenital) Homo sapiens 104-107 16552601-1 2006 The present study employs an in vitro system to analyse the role of steroid hormones in hCG-induced spermiation in two species of anuran amphibian: Rana catesbeiana and Leptodactylus ocellatus. Steroids 68-84 hypertrichosis 2 (generalised, congenital) Homo sapiens 88-91 12018033-11 2002 In that case the corpus luteum is further stimulated by hCG secreted by the blastocyst and the trophoblast-cells until 8/9 weeks of gestational age, when synthesis and secretion of steroids is taken over by the placenta. Steroids 181-189 hypertrichosis 2 (generalised, congenital) Homo sapiens 56-59 16377065-11 2006 We found high normal sex steroid levels in both hCG groups. Steroids 25-32 hypertrichosis 2 (generalised, congenital) Homo sapiens 48-51 22061563-0 2006 Effect of hCG administration on the relationship between testicular steroids and indolic compounds in fat and plasma in entire male pigs. Steroids 68-76 hypertrichosis 2 (generalised, congenital) Homo sapiens 10-13 22061563-1 2006 Our objective was to evaluate pigs injected with human chorionic gonadotropin (hCG) as a potential model to study the effect of high testicular steroid levels on the variation in indolic compounds. Steroids 144-151 hypertrichosis 2 (generalised, congenital) Homo sapiens 79-82 22061563-4 2006 HCG injection increased the levels of testicular steroids (androstenone, testosterone, dehydroepiandrosterone sulphate, oestrone sulphate and oestrone; p<0.001), and indole levels in plasma and fat (p<0.05). Steroids 49-57 hypertrichosis 2 (generalised, congenital) Homo sapiens 0-3 22061563-9 2006 We concluded that hCG-injected pigs might be useful for studying factors responsible for the role of testicular steroids in the occurrence of high indole levels. Steroids 112-120 hypertrichosis 2 (generalised, congenital) Homo sapiens 18-21 22061563-10 2006 Pre-selection of sires based on plasma skatole levels affected both the levels of indolic compounds and testicular steroids, especially in fat, which might have suppressed the response to hCG. Steroids 115-123 hypertrichosis 2 (generalised, congenital) Homo sapiens 188-191 16768150-12 2006 It is suggested that process of hCG secretion could undergo different endocrine regulations between the artificial sex steroid replacement cycles and spontaneous cycles with corpus luteum function. Steroids 119-126 hypertrichosis 2 (generalised, congenital) Homo sapiens 32-35 15836959-11 2005 In summary, findings on the knockout model reaffirm that LH and hCG control uterine functions directly as well as indirectly through increasing ovarian synthesis of steroid hormones and both actions are required for normal uterine biology. Steroids 165-181 hypertrichosis 2 (generalised, congenital) Homo sapiens 64-67 10818405-3 2000 Most of these substances, such as growth factors and cytokines, do not have independent effects on basal androgen production, but exhibit their regulatory potential by modulating hCG- or LH-stimulated steroid production. Steroids 201-208 hypertrichosis 2 (generalised, congenital) Homo sapiens 179-182 12934246-1 2002 UNLABELLED: Several authors have shown the effect of LH or hCG gonadotrophins on steroid secretion in the chick embryo ovary. Steroids 81-88 hypertrichosis 2 (generalised, congenital) Homo sapiens 59-62 12934246-12 2002 PROBLEMS: With LH or hCG nerve fibers and nerve endings were observed both in the right gonad and in the medulla of the left ovary in close contact with the steroid-producing interstitial cells. Steroids 157-164 hypertrichosis 2 (generalised, congenital) Homo sapiens 21-24 11442338-2 2001 Also, in 22 adolescents and in 22 adults from the same sample they evaluated the hCG effect on the gonadal steroids secretion. Steroids 107-115 hypertrichosis 2 (generalised, congenital) Homo sapiens 81-84 11442338-5 2001 The gonadal steroid secretion 2, 24, 48, and 72 h post-hCG was significantly lower in the Tanner 4 adolescents. Steroids 12-19 hypertrichosis 2 (generalised, congenital) Homo sapiens 55-58 11442338-7 2001 In late puberty the LH response to GnRH stimulus is not related either to age or to sexual development, contrary to the FSH response obtained after GnRH and the gonadal steroid response after hCG stimulus, both of which are related to age and patients" sexual development. Steroids 169-176 hypertrichosis 2 (generalised, congenital) Homo sapiens 192-195 7938038-0 1994 Steroid secretion by follicles and cysts from the hypothyroid, hCG-treated rat. Steroids 0-7 hypertrichosis 2 (generalised, congenital) Homo sapiens 63-66 10571964-13 1999 CONCLUSION: It was shown that steroid secretory pattern of follicular cells changed during the year and that the three factors used (pituitary homogenate, hCG and 17alpha,20 betaOH-P) exerted direct influence upon steroids secretion. Steroids 214-222 hypertrichosis 2 (generalised, congenital) Homo sapiens 155-158 9605514-9 1998 Blocking the steroid synthesis of mLTC-1 cells with 86 micromol/l of aminoglutethimide (AMG) partially reversed the down-regulating effect of hCG on the LHR-mRNA. Steroids 13-20 hypertrichosis 2 (generalised, congenital) Homo sapiens 142-145 9605514-13 1998 Since Leydig cell P production is dramatically increased during high-dose stimulation with LH/hCG, due to blockade of C21 steroid side chain cleavage, the present findings offer a function for this steroid in the LHR down-regulation. Steroids 122-129 hypertrichosis 2 (generalised, congenital) Homo sapiens 94-97 9605514-13 1998 Since Leydig cell P production is dramatically increased during high-dose stimulation with LH/hCG, due to blockade of C21 steroid side chain cleavage, the present findings offer a function for this steroid in the LHR down-regulation. Steroids 198-205 hypertrichosis 2 (generalised, congenital) Homo sapiens 94-97 9348220-6 1997 Progesterone production was inhibited by actinomycin D in the hCG-pretreated cells, supporting the proposal that maintaining StAR protein synthesis is required for optimal steroid production in MA-10 mouse Leydig tumor cells. Steroids 172-179 hypertrichosis 2 (generalised, congenital) Homo sapiens 62-65 9561722-3 1997 Obviously, when the testosterone production is low as a consequence of a higher dose of hCG (50 IU/mL), the STM (80%) improves the steroid synthesis five-fold (67.4 ng). Steroids 131-138 hypertrichosis 2 (generalised, congenital) Homo sapiens 88-91 9276342-1 1997 The objective of presented studies was to investigate whether estradiol and progesterone administered in vivo and/or added in vitro can influence the primary myometrial cell culture and how these steroid hormones can affect hCG stimulated cAMP and inositol phosphate production in the porcine uterine myocytes. Steroids 196-212 hypertrichosis 2 (generalised, congenital) Homo sapiens 224-227 9276342-6 1997 The myometrial smooth muscle cells treated with low dose of estradiol and progesterone in vivo responded with much higher accumulation of inositol phosphates to strong (1000 mU/ml) hCG stimulation when compared with those receiving high dose of both steroids. Steroids 250-258 hypertrichosis 2 (generalised, congenital) Homo sapiens 181-184 9276342-9 1997 The presented paper shows that estradiol and progesterone administration in vivo followed by steroid hormone treatment in vitro affects the primary myometrial cells culture and that both steroid hormones modify the basal accumulation of the second messengers: cAMP and IP3 and their answer to hCG stimuli in pigs. Steroids 187-203 hypertrichosis 2 (generalised, congenital) Homo sapiens 293-296 7962333-4 1994 After adrenal suppression by dexamethasone combined with gonadal stimulation with hCG, a dramatic decrease in androgens and adrenal steroids was observed in the peripheral blood. Steroids 132-140 hypertrichosis 2 (generalised, congenital) Homo sapiens 82-85 9593605-5 1998 Steroid hormone responses to hCG stimulation were measured before and 30, 240, and 300 minutes after hCG injection. Steroids 0-15 hypertrichosis 2 (generalised, congenital) Homo sapiens 29-32 7578686-5 1995 When a submaximal dosage of CRH was given together with a maximal dosage of hCG, steroid production was stimulated even more highly in MA-10 cells. Steroids 81-88 hypertrichosis 2 (generalised, congenital) Homo sapiens 76-79 7629236-10 1995 The patterns of these steroids were very different according to plasma hCG levels. Steroids 22-30 hypertrichosis 2 (generalised, congenital) Homo sapiens 71-74 7629236-12 1995 Conversely, for hCG values greater than 3.5 x 10(3) IU/L, hCG levels were negatively correlated (P < 0.05 at least) to all steroid values. Steroids 126-133 hypertrichosis 2 (generalised, congenital) Homo sapiens 16-19 7629236-12 1995 Conversely, for hCG values greater than 3.5 x 10(3) IU/L, hCG levels were negatively correlated (P < 0.05 at least) to all steroid values. Steroids 126-133 hypertrichosis 2 (generalised, congenital) Homo sapiens 58-61 1327203-8 1992 In contrast, these steroids were elevated between Days 3 and 5 of FSH treatment (+/- hCG treatment). Steroids 19-27 hypertrichosis 2 (generalised, congenital) Homo sapiens 85-88 8014608-4 1994 The cyclic and PMSG/hCG-treated rats exhibited some similarities and differences in the general pattern of steroid content. Steroids 107-114 hypertrichosis 2 (generalised, congenital) Homo sapiens 20-23 1996618-8 1991 2 alpha,4 alpha,7-4,5-Epoxy-17-hydroxy-4,17-dimethyl-3-oxo-androstane-2- carbonitrile (epostane), a potent inhibitor of steroid synthesis and ovulation, sharply reduced the synthesis of all five steroids within 30 min after its injection at 3 h after hCG. Steroids 120-127 hypertrichosis 2 (generalised, congenital) Homo sapiens 251-254 1327203-6 1992 Of the serum steroids analyzed, only estradiol and androstenedione concentrations for animals treated with FSH + hCG were consistently elevated above values observed for control HYPOXD rats. Steroids 13-21 hypertrichosis 2 (generalised, congenital) Homo sapiens 113-116 1713581-7 1991 We also show that the ability of these cells to respond to hCG with increased cAMP accumulation and steroid synthesis can be restored with a specific phosphodiesterase inhibitor. Steroids 100-107 hypertrichosis 2 (generalised, congenital) Homo sapiens 59-62 1986971-1 1991 The purpose of this study was to analyze follicular fluid (FF) samples for steroid levels from stimulated and unstimulated cycles triggered with human chorionic gonadotropin (hCG) and to assess the influence of controlled ovarian hyperstimulation and luteinizing hormone/hCG on these levels. Steroids 75-82 hypertrichosis 2 (generalised, congenital) Homo sapiens 175-178 2327831-0 1990 Testicular steroids in spermatic and peripheral veins after single injection of hCG in patients with varicocele. Steroids 11-19 hypertrichosis 2 (generalised, congenital) Homo sapiens 80-83 2291916-3 1990 Specifically, we determined the in vitro secretion of steroids by intact ovarian follicles of unprimed or hCG-primed fish, the direct effects of steroids on maturational competence, and the effects of steroid (cyanoketone), protein (cycloheximide), and RNA (actinomycin D) synthesis inhibitors on hCG-induced maturational competence and steroidogenesis in vitro. Steroids 54-61 hypertrichosis 2 (generalised, congenital) Homo sapiens 106-109 2291916-4 1990 The steroid content of the incubation medium after hCG treatment was measured by RIA. Steroids 4-11 hypertrichosis 2 (generalised, congenital) Homo sapiens 51-54 2512636-2 1989 During hCG treatment steroid conversion in vitro in testicular biopsy material, as well as serum testosterone concentrations increased dramatically. Steroids 21-28 hypertrichosis 2 (generalised, congenital) Homo sapiens 7-10 16726709-0 1989 Ovarian steroid secretion changes after hCG stimulation in early pregnant pigs. Steroids 8-15 hypertrichosis 2 (generalised, congenital) Homo sapiens 40-43 16726709-1 1989 Administration of human chorionic gonadotropin (hCG) to promote ovarian steroid secretion near the time of recognition of pregnancy was evaluated. Steroids 72-79 hypertrichosis 2 (generalised, congenital) Homo sapiens 48-51 2754644-0 1989 Effect of pregnancy, injection of oestradiol benzoate or hCG on steroid concentration and release by pig luteal cells. Steroids 64-71 hypertrichosis 2 (generalised, congenital) Homo sapiens 57-60 2607249-5 1989 Similarly, hCG-induced production of these steroids was decreased by TIM and TCM. Steroids 43-51 hypertrichosis 2 (generalised, congenital) Homo sapiens 11-14 2607249-7 1989 These results suggest: (1) that the thymus contains a factor with a molecular weight of approximately 28 kDa which interacts with hCG in ovarian cells, (2) that the thymus can release active substances which modify steroid secretion by the ovary in vitro and (3) that the reticuloepithelial cells of the thymus are involved in the secretion of factors which modulate the stimulation by hCG of steroidogenesis in ovarian cells. Steroids 215-222 hypertrichosis 2 (generalised, congenital) Homo sapiens 130-133 2834186-1 1988 Using a clonal strain of cultured Leydig tumor cells (designated MA-10), we have examined the effects of Ca+2 on the activation of cAMP accumulation and steroid biosynthesis by hCG. Steroids 153-160 hypertrichosis 2 (generalised, congenital) Homo sapiens 177-180 2852964-8 1988 However, at a maximal dose of human chorionic gonadotropin (hCG), PMA inhibited steroid synthesis at 1 and 2 h but had no significant effect at 3 h. Conversely, PMA had an additive effect on cAMP induced steroidogenesis. Steroids 80-87 hypertrichosis 2 (generalised, congenital) Homo sapiens 60-63 2834186-8 1988 We conclude that Ca+2 is an inhibitor of the hCG-activated adenylate cyclase in Leydig tumor cells, and that this inhibition imposes a limitation on the ability of hCG to activate steroid biosynthesis. Steroids 180-187 hypertrichosis 2 (generalised, congenital) Homo sapiens 164-167 3075167-8 1988 The addition of hCG caused rounding of the cells and was accompanied by the appearance of microvilli and by pronounced steroid-producing organelles. Steroids 119-126 hypertrichosis 2 (generalised, congenital) Homo sapiens 16-19 3938688-3 1985 The steroid replacement regimen can easily be adjusted to maintain pregnancy until the time of luteoplacental shift, based on the close monitoring of the plasma steroid and hCG levels in the pregnant individual. Steroids 4-11 hypertrichosis 2 (generalised, congenital) Homo sapiens 173-176 3115021-8 1987 It was concluded that not only gonadotropin-stimulated steroid synthesis, as previously demonstrated for hCG, but also forskolin and 8-Bromo-cAMP-stimulated steroidogenesis is sensitive to danazol inhibition. Steroids 55-62 hypertrichosis 2 (generalised, congenital) Homo sapiens 105-108 3101068-1 1987 This study was undertaken to examine ovarian steroid production during the early stages of hCG-induced ovarian cyst formation in the hypothyroid rat. Steroids 45-52 hypertrichosis 2 (generalised, congenital) Homo sapiens 91-94 2891876-7 1987 The patterns of the steroid response to hCG were similar in both groups: in the testes and in the plasma, they increased acutely following hCG injection (except testicular androstenedione), then, after 72 h, returned to normal values in the plasma but remained higher than the basal values in the testes. Steroids 20-27 hypertrichosis 2 (generalised, congenital) Homo sapiens 40-43 2891876-7 1987 The patterns of the steroid response to hCG were similar in both groups: in the testes and in the plasma, they increased acutely following hCG injection (except testicular androstenedione), then, after 72 h, returned to normal values in the plasma but remained higher than the basal values in the testes. Steroids 20-27 hypertrichosis 2 (generalised, congenital) Homo sapiens 139-142 2439507-5 1987 Initially, it transiently attenuates the increase in intracellular cAMP and steroid biosynthesis provoked by submaximal concentrations of hCG. Steroids 76-83 hypertrichosis 2 (generalised, congenital) Homo sapiens 138-141 2439507-6 1987 At later times, however, it potentiates the stimulatory effects of submaximal concentrations of hCG on steroid biosynthesis in a synergistic fashion. Steroids 103-110 hypertrichosis 2 (generalised, congenital) Homo sapiens 96-99 3010006-9 1986 After 12 months of buserelin injections, the changes in hCG-stimulated rat testes are an increased ratio of progesterone/17-OH-progesterone (inhibition of 17-hydroxylase), a reduced capacity for secretion of androstenedione and testosterone (block of 17,20-desmolase), and increased 5 alpha-pregnane-3,20-dione (this steroid inhibits the 17,20-desmolase, similarly to progesterone). Steroids 317-324 hypertrichosis 2 (generalised, congenital) Homo sapiens 56-59 3997273-1 1985 The possible mediation by steroids, prostaglandins or protein synthesis on the hCG-induced increase in hormone uptake and interstial fluid volume in the rat testis in vivo was studied following a single iv injection of hCG. Steroids 26-34 hypertrichosis 2 (generalised, congenital) Homo sapiens 79-82 2987616-6 1985 Under stimulation with hCG, there was a rapid response in testicular steroidogenesis, initially seen as a rapid increase in the secretion of unconjugated and sulphated steroids. Steroids 168-176 hypertrichosis 2 (generalised, congenital) Homo sapiens 23-26 2987616-8 1985 Only high doses of hCG, 10-100 ng/ml, were then able to lead to a net accumulation of unconjugated steroids, at 24-36 h of incubation with hCG. Steroids 99-107 hypertrichosis 2 (generalised, congenital) Homo sapiens 19-22 2987616-8 1985 Only high doses of hCG, 10-100 ng/ml, were then able to lead to a net accumulation of unconjugated steroids, at 24-36 h of incubation with hCG. Steroids 99-107 hypertrichosis 2 (generalised, congenital) Homo sapiens 139-142 2581068-0 1985 Changes in plasma steroid levels after single administration of hCG or LHRH agonist analogue in dog and rat. Steroids 18-25 hypertrichosis 2 (generalised, congenital) Homo sapiens 64-67 2581068-7 1985 Moreover, in rats injected with hCG, low plasma steroid levels are present between 4-12 h after injection due to testicular desensitization. Steroids 48-55 hypertrichosis 2 (generalised, congenital) Homo sapiens 32-35 2581068-9 1985 Acute testicular steroidogenic responsiveness to hCG on the dog is, however, different: after stimulation, the levels of plasma dehydroepiandrosterone are maintained at a plateau and slowly decline after 24-48 h. Our data indicate that in dogs, stimulation of testicular steroidogenesis leads to an increase of plasma delta 5-steroid levels while the same stimuli cause, in the rat, a stimulation of delta 4-androgen, particularly testosterone. Steroids 17-24 hypertrichosis 2 (generalised, congenital) Homo sapiens 49-52 2412804-2 1985 The treatment of Leydig cell cultures with bovine LH (bLH), hCG, or with (Bu)2cAMP elicited a dose- and time-dependent induction of renin activity and a concomitant increase in steroid biosynthesis. Steroids 177-184 hypertrichosis 2 (generalised, congenital) Homo sapiens 60-63 3999743-0 1985 Stimulation of the synthesis of steroids and steroid sulphates in human testicular tissue in vitro by hCG and by 8-bromo-cyclic AMP. Steroids 32-40 hypertrichosis 2 (generalised, congenital) Homo sapiens 102-105 2987495-0 1985 Relationship between hCG receptors disappearance and steroid accumulation during long term hCG stimulation in porcine Leydig cell cultures. Steroids 53-60 hypertrichosis 2 (generalised, congenital) Homo sapiens 21-24 2987495-0 1985 Relationship between hCG receptors disappearance and steroid accumulation during long term hCG stimulation in porcine Leydig cell cultures. Steroids 53-60 hypertrichosis 2 (generalised, congenital) Homo sapiens 91-94 2987495-5 1985 A 50% receptor disappearance was obtained for 0.5 ng hCG/ml which led to a steroid accumulation of 50% of the maximal accumulation obtained with 100 ng/ml. Steroids 75-82 hypertrichosis 2 (generalised, congenital) Homo sapiens 53-56 6224978-0 1983 Comparison of serum steroid responses to a single injection of hCG in man and rat. Steroids 20-27 hypertrichosis 2 (generalised, congenital) Homo sapiens 63-66 6317357-10 1984 However, in spite of their changes in density, the Leydig cell bands still showed similar degrees of receptor down-regulation and impairment of the steroid responses to hCG in vitro. Steroids 148-155 hypertrichosis 2 (generalised, congenital) Homo sapiens 169-172 6863482-1 1983 In normal men a single dose of hCG induces an increase in plasma testosterone (T) and 17 alpha-hydroxyprogesterone (17 alpha-OHP) 2-4 h after the injection; after 24-36 h a maximum increase in plasma 17 beta-estradiol (E2) and 17 alpha-OHP occurs followed by a second surge in T after 48-96 h. The present investigation focuses on the effect of a single dose of hCG (3500 IU/m2 body surface) on testicular steroid production in 12 boys aged 13 months to 12 yr. Steroids 406-413 hypertrichosis 2 (generalised, congenital) Homo sapiens 31-34 6224978-1 1983 The responses of peripheral serum steroids to a single injection of hCG (80 IU/kg b wt) were compared in adult male rats and humans. Steroids 34-42 hypertrichosis 2 (generalised, congenital) Homo sapiens 68-71 6224978-4 1983 Transient blockade of C21 steroid side-chain cleavage was seen in both species at about 24-36 h after hCG, which occurred at the same time as the maximum concentration of estradiol in the men. Steroids 26-33 hypertrichosis 2 (generalised, congenital) Homo sapiens 102-105 6861718-11 1983 These studies have indicated that the hCG-induced RNA polymerase activation in the Leydig cell is mediated through nuclear actions of estradiol, since stimulation of the enzymes was prevented by tamoxifen and inhibition of steroid biosynthesis, and was induced by estradiol administration. Steroids 223-230 hypertrichosis 2 (generalised, congenital) Homo sapiens 38-41 6221767-7 1983 Stimulation by hCG led to an increase in apparent steroid production for all steroids, including estrogens, with the greatest quantities seen with DHAS (greater than 200 ng/1 X 10(6) cells/3 h). Steroids 50-57 hypertrichosis 2 (generalised, congenital) Homo sapiens 15-18 6221767-7 1983 Stimulation by hCG led to an increase in apparent steroid production for all steroids, including estrogens, with the greatest quantities seen with DHAS (greater than 200 ng/1 X 10(6) cells/3 h). Steroids 77-85 hypertrichosis 2 (generalised, congenital) Homo sapiens 15-18 6994038-0 1980 [Determination of steroids in the human spermatic vein in the basic state and after stimulation by hCG]. Steroids 18-26 hypertrichosis 2 (generalised, congenital) Homo sapiens 99-102 6896179-5 1982 Whether mitochondria were prepared from the ovaries of rats acutely treated with cycloheximide, hCG, or vehicle, cardiolipin stimulated steroid production to the same absolute value. Steroids 136-143 hypertrichosis 2 (generalised, congenital) Homo sapiens 96-99 6797954-9 1981 The ratios of the steroid concentrations support previous reports that hCG-induced inhibition of 17-hydroxylase, 17--20 desmolase and 3 beta-hydroxysteroid dehydrogenase-delta 4-5 isomerase is decreased during antioestrogen administration. Steroids 18-25 hypertrichosis 2 (generalised, congenital) Homo sapiens 71-74 6832045-9 1983 A 10-day regimen of increasing hCG doses beginning on day 10 of the luteal phase mimicked the steroid hormone secretion patterns observed in control monkeys during early pregnancy. Steroids 94-109 hypertrichosis 2 (generalised, congenital) Homo sapiens 31-34 7124285-2 1982 For this purpose, hCG stimulation of steroid testicular production was performed in 12 boars and fat androstenone concentration subsequently measured. Steroids 37-44 hypertrichosis 2 (generalised, congenital) Homo sapiens 18-21 7192190-0 1980 Response of peripheral serum sex steroids and some of their precursors to a single injection of hCG in adult men. Steroids 33-41 hypertrichosis 2 (generalised, congenital) Homo sapiens 96-99 6446358-4 1980 The releasing kinetic of the 3 steroids under hCG influence was studied; after 12 days of culture, the medium was analysed during 96 hours (8 periods of 12 hours); the steroid production started immediately and showed a progressive increase then slightly slowed down at the end of the 4 days. Steroids 31-39 hypertrichosis 2 (generalised, congenital) Homo sapiens 46-49 7189630-3 1980 Response to hCG was assessed by measurement of steroids in serum collected before and for 5 days after im administration of 10 000 IU hCG. Steroids 47-55 hypertrichosis 2 (generalised, congenital) Homo sapiens 12-15 6446358-4 1980 The releasing kinetic of the 3 steroids under hCG influence was studied; after 12 days of culture, the medium was analysed during 96 hours (8 periods of 12 hours); the steroid production started immediately and showed a progressive increase then slightly slowed down at the end of the 4 days. Steroids 31-38 hypertrichosis 2 (generalised, congenital) Homo sapiens 46-49 6114047-13 1980 The increased dosage of hCG used in this series is considered to be a decisive factor in the induction of ovulation and the maintenance of pregnancies through the abundant steroid production it induced. Steroids 172-179 hypertrichosis 2 (generalised, congenital) Homo sapiens 24-27 986960-7 1976 A peak in the overall incorporation of 14C- acetate into the ten steroids at the 3rd hour after hCG injection, followed by gradual decrease up to the 9th hour was observed. Steroids 65-73 hypertrichosis 2 (generalised, congenital) Homo sapiens 96-99 192755-1 1977 The role of hCG in the regulation of testicular steroid production in human fetuses from 14 to 20 weeks gestational age was studied. Steroids 48-55 hypertrichosis 2 (generalised, congenital) Homo sapiens 12-15 986960-9 1976 Comparable quantitative fluctuations were found with the fractionated incorporation of 14C-acetate into the C21 and C18 steroids in the time sequence following hCG injection. Steroids 120-128 hypertrichosis 2 (generalised, congenital) Homo sapiens 160-163 986960-10 1976 However, the fractionated incorporation into C19 steroids reached to a maximum at the 6th hour after hCG injection. Steroids 49-57 hypertrichosis 2 (generalised, congenital) Homo sapiens 101-104 986960-13 1976 Divergent steroids were formed from radioactive acetate at the 3rd hour after hCG injection. Steroids 10-18 hypertrichosis 2 (generalised, congenital) Homo sapiens 78-81 986960-16 1976 The three androgens were the major steroids formed at the 12th hour after hCG injection. Steroids 35-43 hypertrichosis 2 (generalised, congenital) Homo sapiens 74-77 30689188-4 2019 Induced expression of Stau1 and Gemin 5 in the uterine tissue post hCG treatment at 12 h and 24 h-the duration between ovulation and post-ovulation-suggests their regulation by hCG and/or ovarian steroids, which are required for pregnancy establishment and maintenance. Steroids 196-204 hypertrichosis 2 (generalised, congenital) Homo sapiens 67-70