PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19933497-0 2010 Regulation of monocyte chemotactic protein-1 expression in human endometrial endothelial cells by sex steroids: a potential mechanism for leukocyte recruitment in endometriosis. Steroids 102-110 C-C motif chemokine ligand 2 Homo sapiens 14-44 22523336-0 2012 Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men. Steroids 4-11 C-C motif chemokine ligand 2 Homo sapiens 43-77 22523336-10 2012 The direct adverse effects on MCP1, a chemokine highly linked to the development of metabolic dysfunction, were substantiated in a trial mimicking obesity-related alterations of sex steroid levels in healthy young males. Steroids 182-189 C-C motif chemokine ligand 2 Homo sapiens 30-34 20497022-5 2010 COPD group had higher plasma MCP1 levels than healthy participants (257.0 versus 194.4 pg/mL) in the univariate analysis (P = .005); and in stepwise liner regression analysis after adjustment for age, alcohol, body mass index, cancer history, and steroid use (P = .002; 95% confidence interval [CI]: 30.72-128.02). Steroids 247-254 C-C motif chemokine ligand 2 Homo sapiens 29-33 19933497-7 2010 However, we observed that the sex steroid treatment stimulated MCP-1 mRNA and protein expression in HEECs from women with endometriosis (P < .05). Steroids 34-41 C-C motif chemokine ligand 2 Homo sapiens 63-68 15550762-0 2004 Steroid therapy altered serum levels of CCL2 and CCL5 chemokines in multiple sclerosis patients during relapse. Steroids 0-7 C-C motif chemokine ligand 2 Homo sapiens 40-44 15731299-9 2004 We present evidence for direct and/or indirect roles of steroid hormones on the expression of chemotactic cytokines (interleukin-8 and monocyte chemotactic protein-1) and on the survival versus apoptosis of resident endometrial cells (stromal, epithelial, and endothelial cells) and nonresident cells (leukocytes). Steroids 56-72 C-C motif chemokine ligand 2 Homo sapiens 135-165 18657352-5 2008 RESULTS: A significant increase of IL-10 and decrease of CCL2 serum levels was observed (p=0.0028 and 0.045 respectively) five days after the onset of steroid treatment but not after one month. Steroids 151-158 C-C motif chemokine ligand 2 Homo sapiens 57-61 17995524-2 2007 We and others observed that IgA itself could directly activate mesangial cells to produce monocyte chemotactic peptide-1 (MCP-1), interleukin-6 (IL-6) and transforming growth factor-beta (TGF-beta) and this was suppressed by the treatment with steroid or angiotensin receptor blocker (ARB). Steroids 244-251 C-C motif chemokine ligand 2 Homo sapiens 90-120 15550762-2 2004 The aim of this study was to determine the impact of steroid therapy on the levels of CCL2 and CCL5 chemokines. Steroids 53-60 C-C motif chemokine ligand 2 Homo sapiens 86-90 12411099-7 2002 It was found that steroid and CTX intermittent intravenous pulse therapy reduced the expression of CD68, MCP-1, and MIP-1alpha, but had no effect on MIP-1beta in glomeruli with cellular crescents of patients with LN-CGN. Steroids 18-25 C-C motif chemokine ligand 2 Homo sapiens 105-110 9627299-17 1998 CONCLUSION(S): These findings suggest that MCP-1 may have antineoplastic activity in leiomyomata and that sex steroids may be exerting their growth stimulatory effect in leiomyomata through down-regulation of MCP-1. Steroids 110-118 C-C motif chemokine ligand 2 Homo sapiens 209-214 11240649-7 2000 In serum, IL-6, IL-8 and MCP-1 decreased with the administration of steroids prior to paclitaxel, and increased in the 24 h after paclitaxel. Steroids 68-76 C-C motif chemokine ligand 2 Homo sapiens 25-30 10377035-4 1999 We hypothesized that sex steroids may be involved in the regulation of macrophage migration by regulating MCP-1 expression. Steroids 25-33 C-C motif chemokine ligand 2 Homo sapiens 106-111 35525835-12 2022 CONCLUSIONS: PMX-DHP combined with steroid pulse therapy might reduce GRO, IL-10, IL-1Ra, IL-5, IL-6, and MCP-1 levels in ARF, contributing to better oxygenation in the disorder. Steroids 35-42 C-C motif chemokine ligand 2 Homo sapiens 106-111 8648917-7 1996 Moreover, elevated urinary MCAF levels were dramatically decreased during steroid therapy-induced convalescence in 29 patients examined serially (13.9 +/- 4.5 vs. 5.3 +/- 1.7 pg/ml . Steroids 74-81 C-C motif chemokine ligand 2 Homo sapiens 27-31 1624809-4 1992 Expression of the MCP-1 gene is inducible by activators of the protein kinase A (cAMP) and C (PMA) signal transduction pathways and is differentially regulated by the steroids dexamethasone and retinoic acid. Steroids 167-175 C-C motif chemokine ligand 2 Homo sapiens 18-23 26609908-12 2016 CONCLUSION: Low-dosage steroid therapy reversed or delayed the renal failure progression in severe chronic AAN patients, which may be associated with the suppression of MCP-1 and TGF-beta1 activities. Steroids 23-30 C-C motif chemokine ligand 2 Homo sapiens 169-174 26335292-3 2015 MCP1 2518 A/G genotype was identified by PCR-RFLP in 60 biopsy-proven FSGS patients, 76 steroid sensitive nephrotic syndrome (SSNS) patients, and 96 healthy children. Steroids 88-95 C-C motif chemokine ligand 2 Homo sapiens 0-4 31455510-6 2020 Levels of interleukin (IL)-6, IL-8, and macrophage chemotactic protein 1 (MCP-1) in the cerebrospinal fluid were high at onset and reduced transiently after steroid pulse therapy. Steroids 157-164 C-C motif chemokine ligand 2 Homo sapiens 40-72 31455510-6 2020 Levels of interleukin (IL)-6, IL-8, and macrophage chemotactic protein 1 (MCP-1) in the cerebrospinal fluid were high at onset and reduced transiently after steroid pulse therapy. Steroids 157-164 C-C motif chemokine ligand 2 Homo sapiens 74-79 26630427-11 2016 In addition, animals treated with hydrogel plus steroid showed significant reduction in the number of infiltrating macrophages at the sciatic nerve and reduced expression of the neuroinflammatory chemokine monocyte chemoattractant protein-1 (P < 0.05). Steroids 48-55 C-C motif chemokine ligand 2 Homo sapiens 206-240