PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32866001-1 2020 The protein FKBP52 is a steroid hormone receptor coactivator likely involved in neurodegenerative disease. Steroids 24-31 FKBP prolyl isomerase 4 Homo sapiens 12-18 26858893-1 2015 The steroid receptor (SR) complex contains FKBP51 and FKBP52, which bind to tacrolimus (TAC) and cyclophilin 40, which, in turn, bind to cyclosporine (CYA); these influence the intranuclear mobility of steroid-SR complexes. Steroids 4-11 FKBP prolyl isomerase 4 Homo sapiens 54-60 31661769-1 2019 Previous studies demonstrated that the 52-kDa FK506-binding protein (FKBP52) proline-rich loop is functionally relevant in the regulation of steroid hormone receptor activity. Steroids 141-148 FKBP prolyl isomerase 4 Homo sapiens 69-75 26224894-1 2015 The steroid receptor-associated immunophilins FKBP51, FKBP52, CyP40 and PP5 have specific roles in steroid receptor function that impact steroid hormone-binding affinity, nucleocytoplasmic shuttling and transcriptional activation of target genes in a tissue-specific manner. Steroids 137-152 FKBP prolyl isomerase 4 Homo sapiens 54-60 25986567-1 2015 The steroid receptor-associated TPR cochaperones FKBP51, FKBP52, CyP40 and PP5 have non-redundant roles in steroid receptor function that impact steroid hormone-binding affinity, nucleocyoplasmic shuttling and transcriptional activation of target genes in a tissue-specific manner. Steroids 4-11 FKBP prolyl isomerase 4 Homo sapiens 57-63 25986567-1 2015 The steroid receptor-associated TPR cochaperones FKBP51, FKBP52, CyP40 and PP5 have non-redundant roles in steroid receptor function that impact steroid hormone-binding affinity, nucleocyoplasmic shuttling and transcriptional activation of target genes in a tissue-specific manner. Steroids 107-114 FKBP prolyl isomerase 4 Homo sapiens 57-63 25986567-1 2015 The steroid receptor-associated TPR cochaperones FKBP51, FKBP52, CyP40 and PP5 have non-redundant roles in steroid receptor function that impact steroid hormone-binding affinity, nucleocyoplasmic shuttling and transcriptional activation of target genes in a tissue-specific manner. Steroids 107-114 FKBP prolyl isomerase 4 Homo sapiens 57-63 25132599-0 2015 Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway. Steroids 77-84 FKBP prolyl isomerase 4 Homo sapiens 96-102 25132599-10 2015 In summary, we identify a novel steroid-responsive FKBP52-dependent pathway suppressing the expression and activity of TDO, a central and rate-limiting enzyme in tryptophan metabolism, in human gliomas. Steroids 32-39 FKBP prolyl isomerase 4 Homo sapiens 51-57 27746846-6 2016 Among the 882 selected patients, 621 (70.4%) achieved a House-Brackmann score of I or II; 68% of the patients treated only with steroids achieved HB I or II, versus 70.5% when treated with steroids plus antiviral agents. Steroids 128-136 FKBP prolyl isomerase 4 Homo sapiens 146-156 22921020-2 2012 This steroid response appears to be heritable and alleles in the SFRS3 and FKBP4 genes have recently been suggested to play a role. Steroids 5-12 FKBP prolyl isomerase 4 Homo sapiens 75-80 22921020-3 2012 The purpose of the present study was to perform an independent replication study to determine whether single nucleotide polymorphisms (SNPs) in SFRS3 and FKBP4 are involved in the steroid response. Steroids 180-187 FKBP prolyl isomerase 4 Homo sapiens 154-159 21889356-1 2011 FKBP51 and FKBP52 are diverse regulators of steroid hormone receptor signaling, including receptor maturation, hormone binding and nuclear translocation. Steroids 44-51 FKBP prolyl isomerase 4 Homo sapiens 11-17 17938211-0 2007 Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling. Steroids 86-101 FKBP prolyl isomerase 4 Homo sapiens 25-31 21799260-5 2011 The larger members, FKBP51 and FKBP52, interact with Hsp90 and exhibit chaperone activity that is shown to regulate steroid hormone signalling. Steroids 116-123 FKBP prolyl isomerase 4 Homo sapiens 31-37 20564723-9 2010 Among 83 patients treated with steroids, 67% achieved HB I, 30% HB II-V, and no patients with HB VI. Steroids 31-39 FKBP prolyl isomerase 4 Homo sapiens 54-58 21225812-9 2010 Among 83 patients treated with steroids, 67% achieved HB I, 30% HB II-V, and no patients with HB VI. Steroids 31-39 FKBP prolyl isomerase 4 Homo sapiens 54-58 7510997-4 1994 Immunopurification from cytosol of [3H]steroid-labeled tungstate-stabilized PR with anti-PR immunoadsorbent yielded "9S"-PR species in which hsp90, hsp70 and p59/HBI were present. Steroids 39-46 FKBP prolyl isomerase 4 Homo sapiens 162-165 15985298-13 2005 All six patients who received intravenous steroids for OME-associated FNP received the doses within the first week of presentation and had complete recovery (HB I/VI); three of five patients who did not receive steroids had complete recovery. Steroids 42-50 FKBP prolyl isomerase 4 Homo sapiens 158-165 34112753-1 2021 FKBP4 belongs to the family of immunophilins, which serve as a regulator for steroid receptor activity. Steroids 77-84 FKBP prolyl isomerase 4 Homo sapiens 0-5 34369937-3 2021 FK506-binding protein (FKBP) 51 and FKBP52 are two similar TPR-motif co-chaperones involved in steroid hormone-dependent diseases with different functions. Steroids 95-102 FKBP prolyl isomerase 4 Homo sapiens 36-42