PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35099763-0 2022 A novel NPHS2 mutation (c.865A > G) identified in a Chinese family with steroid-resistant nephrotic syndrome alters subcellular localization of nephrin. Steroids 72-79 NPHS2 stomatin family member, podocin Homo sapiens 8-13 35099763-1 2022 BACKGROUND: NPHS2 is the causative gene of nephrotic syndrome type 2 (MIM 600995) which often clinically manifests as steroid-resistant nephrotic syndrome (SRNS). Steroids 118-125 NPHS2 stomatin family member, podocin Homo sapiens 12-17 32056192-2 2020 It started with the discovery of mutations in the podocin gene in steroid resistant nephrotic syndrome (SRNS). Steroids 66-73 NPHS2 stomatin family member, podocin Homo sapiens 50-57 32691731-1 2020 BACKGROUND: NPHS2 gene variants are associated with focal segmental glomerulosclerosis (FSGS) and steroid-resistant nephrotic syndrome (SRNS). Steroids 98-105 NPHS2 stomatin family member, podocin Homo sapiens 12-17 32129207-0 2020 NPHS2 gene mutations in azerbaijani children with steroid-resistant nephrotic syndrome. Steroids 50-57 NPHS2 stomatin family member, podocin Homo sapiens 0-5 32482922-3 2020 Among the genes involved, the NPHS2 gene has been reported as the causative gene in steroid resistant form of nephrotic syndrome. Steroids 84-91 NPHS2 stomatin family member, podocin Homo sapiens 30-35 32585588-1 2020 Mutations in the NPHS2 gene, encoding podocin, are responsible for the majority of familial cases of steroid-resistant nephrotic syndrome (SRNS), a rare glomerulopathy that rapidly progresses to end-stage renal disease. Steroids 101-108 NPHS2 stomatin family member, podocin Homo sapiens 17-22 32585588-1 2020 Mutations in the NPHS2 gene, encoding podocin, are responsible for the majority of familial cases of steroid-resistant nephrotic syndrome (SRNS), a rare glomerulopathy that rapidly progresses to end-stage renal disease. Steroids 101-108 NPHS2 stomatin family member, podocin Homo sapiens 38-45 28712774-0 2017 Characterization of NPHS2 gene polymorphisms associated to steroid resistance nephrotic syndrome in Indian children. Steroids 59-66 NPHS2 stomatin family member, podocin Homo sapiens 20-25 31529341-0 2019 TRPC6 and NPHS2 gene variants in adult patients with steroid-resistant nephrotic syndrome in North-West of Iran. Steroids 53-60 NPHS2 stomatin family member, podocin Homo sapiens 10-15 31754646-0 2019 The podocin V260E mutation predicts steroid resistant nephrotic syndrome in black South African children with focal segmental glomerulosclerosis. Steroids 36-43 NPHS2 stomatin family member, podocin Homo sapiens 4-11 30241959-1 2019 Mutations in the NPHS2 gene, which encodes the podocyte slit diaphragm protein podocin, cause autosomal recessive steroid-resistant nephrotic syndrome (Online Mendelian Inheritance in Man [OMIM] #600995). Steroids 114-121 NPHS2 stomatin family member, podocin Homo sapiens 17-22 30241959-1 2019 Mutations in the NPHS2 gene, which encodes the podocyte slit diaphragm protein podocin, cause autosomal recessive steroid-resistant nephrotic syndrome (Online Mendelian Inheritance in Man [OMIM] #600995). Steroids 114-121 NPHS2 stomatin family member, podocin Homo sapiens 79-86 30793612-1 2019 OBJECTIVES: The aim of the study was to determine the mutation of the podocin gene (NPHS2) in children with minimal changes diseases (steroid sensitive nephrotic syndrome (NS)) and steroid resistant NS. Steroids 134-141 NPHS2 stomatin family member, podocin Homo sapiens 70-77 30793612-1 2019 OBJECTIVES: The aim of the study was to determine the mutation of the podocin gene (NPHS2) in children with minimal changes diseases (steroid sensitive nephrotic syndrome (NS)) and steroid resistant NS. Steroids 134-141 NPHS2 stomatin family member, podocin Homo sapiens 84-89 30793612-1 2019 OBJECTIVES: The aim of the study was to determine the mutation of the podocin gene (NPHS2) in children with minimal changes diseases (steroid sensitive nephrotic syndrome (NS)) and steroid resistant NS. Steroids 181-188 NPHS2 stomatin family member, podocin Homo sapiens 70-77 30793612-1 2019 OBJECTIVES: The aim of the study was to determine the mutation of the podocin gene (NPHS2) in children with minimal changes diseases (steroid sensitive nephrotic syndrome (NS)) and steroid resistant NS. Steroids 181-188 NPHS2 stomatin family member, podocin Homo sapiens 84-89 30260545-1 2018 NPHS2, encoding podocin, is the major gene implicated in steroid-resistant nephrotic syndrome. Steroids 57-64 NPHS2 stomatin family member, podocin Homo sapiens 0-5 30260545-1 2018 NPHS2, encoding podocin, is the major gene implicated in steroid-resistant nephrotic syndrome. Steroids 57-64 NPHS2 stomatin family member, podocin Homo sapiens 16-23 30450462-0 2018 NPHS2 V260E Is a Frequent Cause of Steroid-Resistant Nephrotic Syndrome in Black South African Children. Steroids 35-42 NPHS2 stomatin family member, podocin Homo sapiens 0-5 31949506-1 2019 BACKGROUND: Mutations in the NPHS2 genes are the main aetiology of early-onset and familial steroid-resistant nephrotic syndrome (SRNS). Steroids 92-99 NPHS2 stomatin family member, podocin Homo sapiens 29-34 29382718-1 2018 Podocin is a key component of the slit diaphragm in the glomerular filtration barrier, and mutations in the podocin-encoding gene NPHS2 are a common cause of hereditary steroid-resistant nephrotic syndrome. Steroids 169-176 NPHS2 stomatin family member, podocin Homo sapiens 108-115 29382718-1 2018 Podocin is a key component of the slit diaphragm in the glomerular filtration barrier, and mutations in the podocin-encoding gene NPHS2 are a common cause of hereditary steroid-resistant nephrotic syndrome. Steroids 169-176 NPHS2 stomatin family member, podocin Homo sapiens 130-135 27573339-0 2017 Novel NPHS2 variant in patients with familial steroid-resistant nephrotic syndrome with early onset, slow progression and dominant inheritance pattern. Steroids 46-53 NPHS2 stomatin family member, podocin Homo sapiens 6-11 26820844-4 2017 Podocin gene (NPHS2) mutations cause childhood-onset steroid-resistant FSGS and MCD to adult-onset FSGS. Steroids 53-60 NPHS2 stomatin family member, podocin Homo sapiens 0-7 26820844-4 2017 Podocin gene (NPHS2) mutations cause childhood-onset steroid-resistant FSGS and MCD to adult-onset FSGS. Steroids 53-60 NPHS2 stomatin family member, podocin Homo sapiens 14-19 28529802-0 2017 R229Q Polymorphism of NPHS2 Gene in Group of Iraqi Children with Steroid-Resistant Nephrotic Syndrome. Steroids 65-72 NPHS2 stomatin family member, podocin Homo sapiens 22-27 27885584-0 2017 WT1 and NPHS2 gene mutation analysis and clinical management of steroid-resistant nephrotic syndrome. Steroids 64-71 NPHS2 stomatin family member, podocin Homo sapiens 8-13 28785586-4 2017 NPHS2 mutations are the most frequent genetic cause of steroid resistant nephrotic syndrome. Steroids 55-62 NPHS2 stomatin family member, podocin Homo sapiens 0-5 28529802-2 2017 The polymorphism R229Q is one of the most commonly reported podocin sequence variations among steroid-resistant nephrotic syndromes (SRNS). Steroids 94-101 NPHS2 stomatin family member, podocin Homo sapiens 60-67 26455708-0 2016 [NPHS2 Mutation analysis study in children with steroid-resistant nephrotic syndrome]. Steroids 48-55 NPHS2 stomatin family member, podocin Homo sapiens 1-6 27193387-4 2016 Mutations in podocin are known to be associated with steroid-resistant NS and rapid progression to end-stage renal disease, thus signifying its role in maintaining SD integrity and podocyte function. Steroids 53-60 NPHS2 stomatin family member, podocin Homo sapiens 13-20 26420286-2 2015 Mutations in more than 24 genes have been associated with nephrotic syndrome in children, although the great majority of steroid-resistant cases have been attributed to mutations in three main genes: NPHS1, NPHS2 and WT1. Steroids 121-128 NPHS2 stomatin family member, podocin Homo sapiens 207-212 25112471-0 2014 NPHS2 variation in Chinese southern infants with late steroid-resistant nephrotic syndrome. Steroids 54-61 NPHS2 stomatin family member, podocin Homo sapiens 0-5 25112471-1 2014 Abstract NPHS2 mutations are responsible for autosomal recessive familial steroid-resistant nephrotic syndrome (SRNS) with minor glomerular abnormalities or focal segmental glomerulosclerosis (FSGS), which is characterized by early childhood onset and rapid progression to chronic renal insufficiency. Steroids 74-81 NPHS2 stomatin family member, podocin Homo sapiens 9-14 24715228-0 2014 The p.R229Q variant of the NPHS2 (podocin) gene in focal segmental glomerulosclerosis and steroid-resistant nephrotic syndrome: a meta-analysis. Steroids 90-97 NPHS2 stomatin family member, podocin Homo sapiens 27-32 24715228-0 2014 The p.R229Q variant of the NPHS2 (podocin) gene in focal segmental glomerulosclerosis and steroid-resistant nephrotic syndrome: a meta-analysis. Steroids 90-97 NPHS2 stomatin family member, podocin Homo sapiens 34-41 24715228-1 2014 While many previous studies have reported an association between the p.R229Q variant of the NPHS2 gene and focal segmental glomerulosclerosis (FSGS) or steroid-resistant nephrotic syndrome (SRNS), a conclusive relationship has not been defined. Steroids 152-159 NPHS2 stomatin family member, podocin Homo sapiens 92-97 24596097-1 2014 Mutations in the NPHS2 gene are a major cause of steroid-resistant nephrotic syndrome, a severe human kidney disorder. Steroids 49-56 NPHS2 stomatin family member, podocin Homo sapiens 17-22 24969201-2 2014 NPHS2 mutations are associated with steroid-resistant nephrotic syndrome (SRNS), with the pathologic variant being focal and segmental glomerulosclerosis (FSGS), an emerging cause of end-stage renal disease in children. Steroids 36-43 NPHS2 stomatin family member, podocin Homo sapiens 0-5 25852895-0 2014 Steroid-resistant nephrotic syndrome with mutations in NPHS2 (podocin): report from a three-generation family. Steroids 0-7 NPHS2 stomatin family member, podocin Homo sapiens 55-60 25852895-0 2014 Steroid-resistant nephrotic syndrome with mutations in NPHS2 (podocin): report from a three-generation family. Steroids 0-7 NPHS2 stomatin family member, podocin Homo sapiens 62-69 24519673-0 2014 NPHS2 R229Q polymorphism in steroid resistant nephrotic syndrome: is it responsive to immunosuppressive therapy? Steroids 28-35 NPHS2 stomatin family member, podocin Homo sapiens 0-5 24519673-4 2014 Mutational analysis of NPHS2 gene was performed in 20 sporadic idiopathic SRNS, 90 steroid-sensitive nephrotic syndrome (SSNS) and 50 normal controls. Steroids 83-90 NPHS2 stomatin family member, podocin Homo sapiens 23-28 24878955-0 2014 Re: NPHS2 gene in steroid-resistant nephrotic syndrome: prevalence, clinical course, and mutational spectrum in south-west Iranian children. Steroids 18-25 NPHS2 stomatin family member, podocin Homo sapiens 4-9 24674236-3 2014 Mutations in NPHS2, which encodes for podocin, an integral membrane protein of the glomerular epithelial cells (podocytes), represent a frequent cause of steroid-resistant nephrotic syndrome worldwide. Steroids 154-161 NPHS2 stomatin family member, podocin Homo sapiens 13-18 24674236-3 2014 Mutations in NPHS2, which encodes for podocin, an integral membrane protein of the glomerular epithelial cells (podocytes), represent a frequent cause of steroid-resistant nephrotic syndrome worldwide. Steroids 154-161 NPHS2 stomatin family member, podocin Homo sapiens 38-45 24856380-0 2014 Retrospective mutational analysis of NPHS1, NPHS2, WT1 and LAMB2 in children with steroid-resistant focal segmental glomerulosclerosis - a single-centre experience. Steroids 82-89 NPHS2 stomatin family member, podocin Homo sapiens 44-49 24856380-9 2014 Results indicate possible clustering of causative NPHS2 mutations in FSGS-proven SRNS with onset before age one year old, and provide additional evidence that patients with childhood steroid-resistant nephrotic syndrome due to focal segmental glomerulosclerosis should first undergo analysis of NPHS2 coding sequence and WT1 exons 8 and 9 and surrounding exon/intron boundary sequences, followed by gender genotyping. Steroids 183-190 NPHS2 stomatin family member, podocin Homo sapiens 50-55 24856380-9 2014 Results indicate possible clustering of causative NPHS2 mutations in FSGS-proven SRNS with onset before age one year old, and provide additional evidence that patients with childhood steroid-resistant nephrotic syndrome due to focal segmental glomerulosclerosis should first undergo analysis of NPHS2 coding sequence and WT1 exons 8 and 9 and surrounding exon/intron boundary sequences, followed by gender genotyping. Steroids 183-190 NPHS2 stomatin family member, podocin Homo sapiens 295-300 24559085-4 2014 Genetic mutations of podocin result in steroid resistant FSGS. Steroids 39-46 NPHS2 stomatin family member, podocin Homo sapiens 21-28 24509478-0 2014 Mutation-dependent recessive inheritance of NPHS2-associated steroid-resistant nephrotic syndrome. Steroids 61-68 NPHS2 stomatin family member, podocin Homo sapiens 44-49 24464702-6 2014 Podocin is an important glomerular integral membrane protein thought to play a key role in steroid resistant nephrotic syndrome. Steroids 91-98 NPHS2 stomatin family member, podocin Homo sapiens 0-7 24413855-1 2013 BACKGROUND AND OBJECTIVES: Mutations in several genes are known to cause steroid-resistant nephrotic syndome (SRNS), most commonly in NPHS1, NPHS2, and WT1. Steroids 73-80 NPHS2 stomatin family member, podocin Homo sapiens 141-146 24227627-0 2014 NPHS2 mutations in steroid-resistant nephrotic syndrome: a mutation update and the associated phenotypic spectrum. Steroids 19-26 NPHS2 stomatin family member, podocin Homo sapiens 0-5 24227627-1 2014 Mutations in the NPHS2 gene encoding podocin are implicated in an autosomal-recessive form of nonsyndromic steroid-resistant nephrotic syndrome in both pediatric and adult patients. Steroids 107-114 NPHS2 stomatin family member, podocin Homo sapiens 17-22 24227627-1 2014 Mutations in the NPHS2 gene encoding podocin are implicated in an autosomal-recessive form of nonsyndromic steroid-resistant nephrotic syndrome in both pediatric and adult patients. Steroids 107-114 NPHS2 stomatin family member, podocin Homo sapiens 37-44 24231487-3 2013 We report a child aged 4 months with steroid-resistant NS who had polymorphism of NPHS1 (E117K) and mutation of NPHS2 (P118L). Steroids 37-44 NPHS2 stomatin family member, podocin Homo sapiens 112-117 23800802-1 2013 BACKGROUND: The pathogenicity of the NPHS2 homozygous p.R229Q variant in steroid-resistant nephrotic syndrome (SRNS) is doubtful. Steroids 73-80 NPHS2 stomatin family member, podocin Homo sapiens 37-42 23982418-1 2013 BACKGROUND: Podocin is a key protein involved in the pathogenesis of steroid-resistant nephrotic syndrome and/or focal segmental glomerulosclerosis (FSGS) and is characterized by a high rate of early recurrence after renal transplantation (RTx) in children and adults. Steroids 69-76 NPHS2 stomatin family member, podocin Homo sapiens 12-19 24072147-0 2013 NPHS2 gene in steroid-resistant nephrotic syndrome: prevalence, clinical course, and mutational spectrum in South-West Iranian children. Steroids 14-21 NPHS2 stomatin family member, podocin Homo sapiens 0-5 24072147-1 2013 INTRODUCTION: Mutations in podocin (NPHS2) gene have the key role in the pathogenesis of steroid-resistant nephrotic syndrome (SRNS) in children, but data is scarce regarding their prevalence and natural course among different all ethnic groups. Steroids 89-96 NPHS2 stomatin family member, podocin Homo sapiens 27-34 24072147-1 2013 INTRODUCTION: Mutations in podocin (NPHS2) gene have the key role in the pathogenesis of steroid-resistant nephrotic syndrome (SRNS) in children, but data is scarce regarding their prevalence and natural course among different all ethnic groups. Steroids 89-96 NPHS2 stomatin family member, podocin Homo sapiens 36-41 24072153-0 2013 R229Q polymorphism of NPHS2 gene in patients with late-onset steroid-resistance nephrotic syndrome: a preliminary study. Steroids 61-68 NPHS2 stomatin family member, podocin Homo sapiens 22-27 23913389-0 2013 Mutations in NPHS2 (podocin) in Mexican children with nephrotic syndrome who respond to standard steroid treatment. Steroids 97-104 NPHS2 stomatin family member, podocin Homo sapiens 13-18 23515051-11 2013 Thus, screening of the entire coding sequence of NPHS2 and exons 8-9 of WT1 appears to be the most rational and cost-effective screening approach in sporadic juvenile steroid-resistant nephrotic syndrome. Steroids 167-174 NPHS2 stomatin family member, podocin Homo sapiens 49-54 23913389-0 2013 Mutations in NPHS2 (podocin) in Mexican children with nephrotic syndrome who respond to standard steroid treatment. Steroids 97-104 NPHS2 stomatin family member, podocin Homo sapiens 20-27 23913389-2 2013 Mutations in the NPHS2 gene that encodes podocin have been described as responsible for steroid-resistant nephrotic syndrome. Steroids 88-95 NPHS2 stomatin family member, podocin Homo sapiens 17-22 23913389-2 2013 Mutations in the NPHS2 gene that encodes podocin have been described as responsible for steroid-resistant nephrotic syndrome. Steroids 88-95 NPHS2 stomatin family member, podocin Homo sapiens 41-48 23913389-7 2013 Podocin heterozygous missense mutations L139R and L142P were found; the former was found in both steroid-sensitive and steroid-resistant children, while the latter was found in a steroid-resistant child. Steroids 97-104 NPHS2 stomatin family member, podocin Homo sapiens 0-7 23913389-7 2013 Podocin heterozygous missense mutations L139R and L142P were found; the former was found in both steroid-sensitive and steroid-resistant children, while the latter was found in a steroid-resistant child. Steroids 119-126 NPHS2 stomatin family member, podocin Homo sapiens 0-7 23913389-7 2013 Podocin heterozygous missense mutations L139R and L142P were found; the former was found in both steroid-sensitive and steroid-resistant children, while the latter was found in a steroid-resistant child. Steroids 119-126 NPHS2 stomatin family member, podocin Homo sapiens 0-7 23242530-0 2013 NPHS2 p.V290M mutation in late-onset steroid-resistant nephrotic syndrome. Steroids 37-44 NPHS2 stomatin family member, podocin Homo sapiens 0-5 23648087-1 2013 BACKGROUND: Steroid resistant nephrotic syndrome is a severe hereditary disease often caused by mutations in the NPHS2 gene. Steroids 12-19 NPHS2 stomatin family member, podocin Homo sapiens 113-118 22565185-1 2012 BACKGROUND: Mutations in the NPHS1 and NPHS2 genes are among the main causes of early-onset and familial steroid resistant nephrotic syndrome respectively. Steroids 105-112 NPHS2 stomatin family member, podocin Homo sapiens 39-44 23437316-1 2013 Mutations in the gene NPHS2 are the most common cause of hereditary steroid-resistant nephrotic syndrome. Steroids 68-75 NPHS2 stomatin family member, podocin Homo sapiens 22-27 22080622-0 2012 NPHS2 mutations in Indian children with sporadic early steroid resistant nephrotic syndrome. Steroids 55-62 NPHS2 stomatin family member, podocin Homo sapiens 0-5 22080622-1 2012 We examined the frequency and spectrum of podocin NPHS2 mutations in Indian children with sporadic steroid resistant nephrotic syndrome (SRNS). Steroids 100-107 NPHS2 stomatin family member, podocin Homo sapiens 42-49 22080622-1 2012 We examined the frequency and spectrum of podocin NPHS2 mutations in Indian children with sporadic steroid resistant nephrotic syndrome (SRNS). Steroids 100-107 NPHS2 stomatin family member, podocin Homo sapiens 50-55 20947785-0 2011 Clinical value of NPHS2 analysis in early- and adult-onset steroid-resistant nephrotic syndrome. Steroids 59-66 NPHS2 stomatin family member, podocin Homo sapiens 18-23 22388834-7 2012 Genetic forms of INS, with mutation of the NPHS1 and NPHS2 genes encoding nephrin and podocin, are mostly steroid resistant and very rarely recur in the transplant. Steroids 106-113 NPHS2 stomatin family member, podocin Homo sapiens 53-58 22388834-7 2012 Genetic forms of INS, with mutation of the NPHS1 and NPHS2 genes encoding nephrin and podocin, are mostly steroid resistant and very rarely recur in the transplant. Steroids 106-113 NPHS2 stomatin family member, podocin Homo sapiens 86-93 21499232-1 2011 Podocin is a critical component of the glomerular filtration barrier, its mutations causing recessive steroid-resistant nephrotic syndrome. Steroids 102-109 NPHS2 stomatin family member, podocin Homo sapiens 0-7 23013956-0 2012 NPHS2 gene mutation in an Iranian family with familial steroid-resistant nephrotic syndrome. Steroids 55-62 NPHS2 stomatin family member, podocin Homo sapiens 0-5 20947785-5 2011 RESULTS: Compound heterozygous or homozygous NPHS2 pathogenic mutations were identified in seven childhood-onset steroid-resistant nephrotic syndrome (SRNS) cases. Steroids 113-120 NPHS2 stomatin family member, podocin Homo sapiens 45-50 20442690-1 2010 In Chinese children with steroid-resistant nephrotic syndrome (SRNS), it was reported that NPHS2 mutation was detected in 4.3%, which was lower than that in Caucasians (10-30%). Steroids 25-32 NPHS2 stomatin family member, podocin Homo sapiens 91-96 20382325-2 2010 Recently, the causes of many kidney diseases have been shown to be single-gene defects-eg, steroid-resistant nephrotic syndrome, which is caused by podocin mutations in about 25% of children and nearly 15% of adults with the disease. Steroids 91-98 NPHS2 stomatin family member, podocin Homo sapiens 148-155 20507940-1 2010 Mutations in NPHS1, which encodes nephrin, are the main causes of congenital nephrotic syndrome (CNS) in Finnish patients, whereas mutations in NPHS2, which encodes podocin, are typically responsible for childhood-onset steroid-resistant nephrotic syndrome in European populations. Steroids 220-227 NPHS2 stomatin family member, podocin Homo sapiens 144-149 19371226-0 2009 Nucleotide variations in the NPHS2 gene in Greek children with steroid-resistant nephrotic syndrome. Steroids 63-70 NPHS2 stomatin family member, podocin Homo sapiens 29-34 21171529-0 2010 Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation. Steroids 62-69 NPHS2 stomatin family member, podocin Homo sapiens 106-113 21171529-0 2010 Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation. Steroids 62-69 NPHS2 stomatin family member, podocin Homo sapiens 115-120 21171529-1 2010 Podocin mutations (NPHS2 gene) are mostly responsible for steroid-resistant nephrotic syndrome (SRNS) of childhood onset. Steroids 58-65 NPHS2 stomatin family member, podocin Homo sapiens 0-7 21171529-1 2010 Podocin mutations (NPHS2 gene) are mostly responsible for steroid-resistant nephrotic syndrome (SRNS) of childhood onset. Steroids 58-65 NPHS2 stomatin family member, podocin Homo sapiens 19-24 19495806-1 2009 Autosomal recessive steroid-resistant nephrotic syndrome (NS) is a rare, genetically determined nephropathy caused mainly by a mutation in the NPHS2 gene. Steroids 20-27 NPHS2 stomatin family member, podocin Homo sapiens 143-148 19371226-1 2009 Mutations in the NPHS2 gene, encoding podocin, are a major cause of autosomal-recessive steroid-resistant nephrotic syndrome (SRNS) in childhood, accounting for up to 30% of sporadic and 20-40% of familial cases. Steroids 88-95 NPHS2 stomatin family member, podocin Homo sapiens 17-22 19371226-1 2009 Mutations in the NPHS2 gene, encoding podocin, are a major cause of autosomal-recessive steroid-resistant nephrotic syndrome (SRNS) in childhood, accounting for up to 30% of sporadic and 20-40% of familial cases. Steroids 88-95 NPHS2 stomatin family member, podocin Homo sapiens 38-45 19395786-0 2009 NPHS2 mutations in children with steroid-resistant nephrotic syndrome. Steroids 33-40 NPHS2 stomatin family member, podocin Homo sapiens 0-5 19395786-2 2009 Since the identification of the NPHS2 gene, various investigators have demonstrated that its mutation is an important cause of steroid-resistant nephrotic syndrome. Steroids 127-134 NPHS2 stomatin family member, podocin Homo sapiens 32-37 19395786-3 2009 We aimed to evaluate frequency and spectrum of podocin mutations in the Iranian children with steroid-resistant nephritic syndrome. Steroids 94-101 NPHS2 stomatin family member, podocin Homo sapiens 47-54 19395786-11 2009 Other exons of podocin or other podocyte proteins in Iranian children may play a role in pathogenesis of steroid-resistant nephritic syndrome. Steroids 105-112 NPHS2 stomatin family member, podocin Homo sapiens 15-22 18216321-0 2008 Specific podocin mutations correlate with age of onset in steroid-resistant nephrotic syndrome. Steroids 58-65 NPHS2 stomatin family member, podocin Homo sapiens 9-16 19145239-0 2009 Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant. Steroids 43-50 NPHS2 stomatin family member, podocin Homo sapiens 100-105 19145239-1 2009 Mutations of NPHS2, encoding podocin, are the main cause of autosomal recessive steroid-resistant nephrotic syndrome (NS) presenting in childhood. Steroids 80-87 NPHS2 stomatin family member, podocin Homo sapiens 13-18 19145239-1 2009 Mutations of NPHS2, encoding podocin, are the main cause of autosomal recessive steroid-resistant nephrotic syndrome (NS) presenting in childhood. Steroids 80-87 NPHS2 stomatin family member, podocin Homo sapiens 29-36 19145239-2 2009 Adult-onset steroid-resistant NS has been described in patients heterozygous for a pathogenic NPHS2 mutation together with the p.R229Q variant. Steroids 12-19 NPHS2 stomatin family member, podocin Homo sapiens 94-99 19573440-0 2009 [Genetic variations of NPHS2 and WT1 genes in 15 Chinese children with sporadic steroid-resistant nephrotic syndrome]. Steroids 80-87 NPHS2 stomatin family member, podocin Homo sapiens 23-28 20001346-0 2009 A novel mutation in NPHS2 gene identified in a Chinese pedigree with autosomal recessive steroid-resistant nephrotic syndrome. Steroids 89-96 NPHS2 stomatin family member, podocin Homo sapiens 20-25 18334793-1 2008 OBJECTIVE: To uncover the frequency and the spectrum of NPHS2 mutations in Egyptian children with non familial steroid-resistant nephrotic syndrome (SRNS). Steroids 111-118 NPHS2 stomatin family member, podocin Homo sapiens 56-61 18499321-1 2008 BACKGROUND: Rare mutations in nephrosis 2 (NPHS2), encoding podocin, are found in patients with familial and sporadic steroid-resistant nephrotic syndrome and focal segmental glomerular sclerosis. Steroids 118-125 NPHS2 stomatin family member, podocin Homo sapiens 43-48 18499321-1 2008 BACKGROUND: Rare mutations in nephrosis 2 (NPHS2), encoding podocin, are found in patients with familial and sporadic steroid-resistant nephrotic syndrome and focal segmental glomerular sclerosis. Steroids 118-125 NPHS2 stomatin family member, podocin Homo sapiens 60-67 18823551-2 2008 Homozygous or compound heterozygous mutations in the podocin gene NPHS2 are found in 10-30% of pediatric cases of steroid resistant nephrosis and/or FSGS. Steroids 114-121 NPHS2 stomatin family member, podocin Homo sapiens 53-60 18823551-2 2008 Homozygous or compound heterozygous mutations in the podocin gene NPHS2 are found in 10-30% of pediatric cases of steroid resistant nephrosis and/or FSGS. Steroids 114-121 NPHS2 stomatin family member, podocin Homo sapiens 66-71 18543005-0 2008 Low prevalence of NPHS2 mutations in African American children with steroid-resistant nephrotic syndrome. Steroids 68-75 NPHS2 stomatin family member, podocin Homo sapiens 18-23 18392643-0 2008 NPHS2 screening with SURVEYOR in Hellenic children with steroid-resistant nephrotic syndrome. Steroids 56-63 NPHS2 stomatin family member, podocin Homo sapiens 0-5 19099831-0 2008 [Mutations in NPHS2 in familial steroid-resistant nephrotic syndrome in Southern Chinese Han ethnic group]. Steroids 32-39 NPHS2 stomatin family member, podocin Homo sapiens 14-19 18216321-1 2008 Mutations in the gene encoding podocin (NPHS2) cause autosomal recessive steroid-resistant nephrotic syndrome (SRNS). Steroids 73-80 NPHS2 stomatin family member, podocin Homo sapiens 31-38 18216321-1 2008 Mutations in the gene encoding podocin (NPHS2) cause autosomal recessive steroid-resistant nephrotic syndrome (SRNS). Steroids 73-80 NPHS2 stomatin family member, podocin Homo sapiens 40-45 17934764-0 2008 WT1 and NPHS2 mutations in Korean children with steroid-resistant nephrotic syndrome. Steroids 48-55 NPHS2 stomatin family member, podocin Homo sapiens 8-13 18000687-0 2008 Clinical course and NPHS2 analysis in patients with late steroid-resistant nephrotic syndrome. Steroids 57-64 NPHS2 stomatin family member, podocin Homo sapiens 20-25 17899208-4 2007 The aim of this study was to screen for podocin mutations in Turkish patients with steroid-resistant NS (SRNS) and to compare it with other published series. Steroids 83-90 NPHS2 stomatin family member, podocin Homo sapiens 40-47 17942957-1 2007 Mutations in NPHS2, the gene that encodes podocin, are well-established causes of both familial and sporadic steroid-resistant focal segmental glomerulosclerosis (FSGS) in the pediatric population, but have not been well-characterized in late-onset disease. Steroids 109-116 NPHS2 stomatin family member, podocin Homo sapiens 13-18 17942957-1 2007 Mutations in NPHS2, the gene that encodes podocin, are well-established causes of both familial and sporadic steroid-resistant focal segmental glomerulosclerosis (FSGS) in the pediatric population, but have not been well-characterized in late-onset disease. Steroids 109-116 NPHS2 stomatin family member, podocin Homo sapiens 42-49 17216259-0 2007 Mutational analysis of NPHS2 and WT1 in frequently relapsing and steroid-dependent nephrotic syndrome. Steroids 65-72 NPHS2 stomatin family member, podocin Homo sapiens 23-28 17216259-3 2007 Mutations in NPHS2 account for more than 28% of all cases of steroid-resistant nephrotic syndrome (SRNS) and dominant mutations in WT1 for 5%; while mutations are absent from children with uncomplicated SSNS. Steroids 61-68 NPHS2 stomatin family member, podocin Homo sapiens 13-18 17699384-1 2007 Recessive NPHS2 (podocin) mutations account for up to approximately 30% of steroid-resistant idiopathic FSGS in children and are associated with a reduced risk for disease recurrence after renal transplantation. Steroids 75-82 NPHS2 stomatin family member, podocin Homo sapiens 10-15 17699384-1 2007 Recessive NPHS2 (podocin) mutations account for up to approximately 30% of steroid-resistant idiopathic FSGS in children and are associated with a reduced risk for disease recurrence after renal transplantation. Steroids 75-82 NPHS2 stomatin family member, podocin Homo sapiens 17-24 16810518-0 2006 Analysis of NPHS2 mutations in Turkish steroid-resistant nephrotic syndrome patients. Steroids 39-46 NPHS2 stomatin family member, podocin Homo sapiens 12-17 17211152-9 2007 The results demonstrate that NPHS1 and NPHS2 mutations are also present in Chinese sporadic NS patients, suggesting that genetic changes of nephrin and podocin may play pathogenetic roles in some patients with sporadic steroid resistant NS. Steroids 219-226 NPHS2 stomatin family member, podocin Homo sapiens 39-44 17211152-9 2007 The results demonstrate that NPHS1 and NPHS2 mutations are also present in Chinese sporadic NS patients, suggesting that genetic changes of nephrin and podocin may play pathogenetic roles in some patients with sporadic steroid resistant NS. Steroids 219-226 NPHS2 stomatin family member, podocin Homo sapiens 152-159 16721582-1 2006 Mutations in the NPHS2 gene, which encodes podocin, are associated with steroid-resistant nephrotic syndrome in childhood. Steroids 72-79 NPHS2 stomatin family member, podocin Homo sapiens 17-22 16721582-1 2006 Mutations in the NPHS2 gene, which encodes podocin, are associated with steroid-resistant nephrotic syndrome in childhood. Steroids 72-79 NPHS2 stomatin family member, podocin Homo sapiens 43-50 16810518-1 2006 Mutations in the NPHS2 gene are a frequent cause of familial and sporadic steroid-resistant nephrotic syndrome (SRNS). Steroids 74-81 NPHS2 stomatin family member, podocin Homo sapiens 17-22 16572591-4 2006 We sequenced NPHS2 promoter region from -628 to ATG in a large cohort of 260 nephrotic patients (161 with FSGS) who were presenting proteinuria from moderate to severe and were receiving or had received modular therapies according to their sensitivity to steroids and other immune modulators. Steroids 255-263 NPHS2 stomatin family member, podocin Homo sapiens 13-18 16874699-1 2006 BACKGROUND: Mutations in the NPHS2 gene encoding the protein podocin have recently been found in a recessive form of steroid-resistant nephrotic syndrome. Steroids 117-124 NPHS2 stomatin family member, podocin Homo sapiens 29-34 16874699-1 2006 BACKGROUND: Mutations in the NPHS2 gene encoding the protein podocin have recently been found in a recessive form of steroid-resistant nephrotic syndrome. Steroids 117-124 NPHS2 stomatin family member, podocin Homo sapiens 61-68 16481888-3 2006 Mutations in the podocin gene, NPHS2, have been shown in familial and sporadic forms of steroid-resistant nephrotic syndrome, including focal segmental glomerulosclerosis. Steroids 88-95 NPHS2 stomatin family member, podocin Homo sapiens 17-24 16481888-3 2006 Mutations in the podocin gene, NPHS2, have been shown in familial and sporadic forms of steroid-resistant nephrotic syndrome, including focal segmental glomerulosclerosis. Steroids 88-95 NPHS2 stomatin family member, podocin Homo sapiens 31-36 16291839-0 2006 The heart of children with steroid-resistant nephrotic syndrome: is it all podocin? Steroids 27-34 NPHS2 stomatin family member, podocin Homo sapiens 75-82 16291839-1 2006 Mutations in the gene NPHS2 encoding podocin are responsible for a recessive form of steroid-resistant nephrotic syndrome (SRNS). Steroids 85-92 NPHS2 stomatin family member, podocin Homo sapiens 22-27 16291839-1 2006 Mutations in the gene NPHS2 encoding podocin are responsible for a recessive form of steroid-resistant nephrotic syndrome (SRNS). Steroids 85-92 NPHS2 stomatin family member, podocin Homo sapiens 37-44 16898497-0 2006 [Heterozygotic mutation in NPHS2 gene as a cause of familial steroid resistant nephrotic syndrome in two siblings--case report]. Steroids 61-68 NPHS2 stomatin family member, podocin Homo sapiens 27-32 16752799-7 2006 It was concluded that patients with steroid resistant nephrotic syndrome (SRNS) with homozygous or compound heterozygous mutations in NPHS2 have reduced risk for recurrence of focal segmental glomerulosclerosis (FSGS) in renal transplant (only 8% in comparison with 35% in patients without mutation in NPHS2). Steroids 36-43 NPHS2 stomatin family member, podocin Homo sapiens 134-139 16752799-7 2006 It was concluded that patients with steroid resistant nephrotic syndrome (SRNS) with homozygous or compound heterozygous mutations in NPHS2 have reduced risk for recurrence of focal segmental glomerulosclerosis (FSGS) in renal transplant (only 8% in comparison with 35% in patients without mutation in NPHS2). Steroids 36-43 NPHS2 stomatin family member, podocin Homo sapiens 302-307 15769810-0 2005 Mutations in NPHS2 in sporadic steroid-resistant nephrotic syndrome in Chinese children. Steroids 31-38 NPHS2 stomatin family member, podocin Homo sapiens 13-18 16286890-8 2005 Mutations of NPHS2 were detected in 26-38% of familial autosomal recessive steroid-resistant NS (SRNS), 6-19% of sporadic cases of SRNS, and in few adult patients with FSGS. Steroids 75-82 NPHS2 stomatin family member, podocin Homo sapiens 13-18 15769810-1 2005 BACKGROUND: Since the identification of the NPHS2 gene, various investigators have demonstrated that an NPHS2 mutation is a frequent cause of sporadic steroid-resistant nephrotic syndrome (SRNS), and occurs in 10.5-28% of children with the syndrome. Steroids 151-158 NPHS2 stomatin family member, podocin Homo sapiens 44-49 15769810-1 2005 BACKGROUND: Since the identification of the NPHS2 gene, various investigators have demonstrated that an NPHS2 mutation is a frequent cause of sporadic steroid-resistant nephrotic syndrome (SRNS), and occurs in 10.5-28% of children with the syndrome. Steroids 151-158 NPHS2 stomatin family member, podocin Homo sapiens 104-109 15322893-1 2004 Since the identification of the NPHS2 gene,which encodes podocin, several groups from European, Middle Eastern, and North American countries have reported NPHS2 mutations in families with steroid-resistant nephrotic syndrome (SRNS) or focal segmental glomerulo sclerosis (FSGS). Steroids 188-195 NPHS2 stomatin family member, podocin Homo sapiens 32-37 15780077-2 2005 Mutations of NPHS1 and NPHS2, which encode the slit diaphragm components nephrin and podocin, cause CNS and autosomal-recessive familial steroid-resistant nephrotic syndrome, respectively. Steroids 137-144 NPHS2 stomatin family member, podocin Homo sapiens 23-28 15780077-2 2005 Mutations of NPHS1 and NPHS2, which encode the slit diaphragm components nephrin and podocin, cause CNS and autosomal-recessive familial steroid-resistant nephrotic syndrome, respectively. Steroids 137-144 NPHS2 stomatin family member, podocin Homo sapiens 85-92 16050398-4 2005 Using a positional cloning approach, our group identified a gene, NPHS2, involved in a specific entity of familial SRNS characterized by early onset, complete steroid-resistance, rapid progression to ESRD and no recurrence after renal transplantation. Steroids 159-166 NPHS2 stomatin family member, podocin Homo sapiens 66-71 15503167-4 2004 It is now well recognized that podocin mutations are found in 10%-30% of sporadic cases of steroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis. Steroids 91-98 NPHS2 stomatin family member, podocin Homo sapiens 31-38 15496146-2 2004 The gene encoding podocin, NPHS2, is mutated in patients with autosomal-recessive steroid-resistant nephrotic syndrome (SRN). Steroids 82-89 NPHS2 stomatin family member, podocin Homo sapiens 18-25 15496146-2 2004 The gene encoding podocin, NPHS2, is mutated in patients with autosomal-recessive steroid-resistant nephrotic syndrome (SRN). Steroids 82-89 NPHS2 stomatin family member, podocin Homo sapiens 27-32 15322893-1 2004 Since the identification of the NPHS2 gene,which encodes podocin, several groups from European, Middle Eastern, and North American countries have reported NPHS2 mutations in families with steroid-resistant nephrotic syndrome (SRNS) or focal segmental glomerulo sclerosis (FSGS). Steroids 188-195 NPHS2 stomatin family member, podocin Homo sapiens 57-64 15322893-1 2004 Since the identification of the NPHS2 gene,which encodes podocin, several groups from European, Middle Eastern, and North American countries have reported NPHS2 mutations in families with steroid-resistant nephrotic syndrome (SRNS) or focal segmental glomerulo sclerosis (FSGS). Steroids 188-195 NPHS2 stomatin family member, podocin Homo sapiens 155-160 15504144-0 2004 A novel NPHS2 gene mutation in Turkish children with familial steroid-resistant nephrotic syndrome. Steroids 62-69 NPHS2 stomatin family member, podocin Homo sapiens 8-13 15327385-1 2004 BACKGROUND: Mutations in NPHS2, encoding podocin, are a prevalent cause of autosomal-recessive steroid-resistant nephrotic syndrome (SRNS). Steroids 95-102 NPHS2 stomatin family member, podocin Homo sapiens 25-30 15500125-4 2004 Podocin was identified as a gene product of NPHS2, a mutated gene in patients with autosomal recessive steroid-resistant nephrotic syndrome. Steroids 103-110 NPHS2 stomatin family member, podocin Homo sapiens 0-7 15500125-4 2004 Podocin was identified as a gene product of NPHS2, a mutated gene in patients with autosomal recessive steroid-resistant nephrotic syndrome. Steroids 103-110 NPHS2 stomatin family member, podocin Homo sapiens 44-49 15059485-0 2004 [A novel mutation of NPHS2 identified in a Chinese family with steroid-resistant nephrotic syndrome]. Steroids 63-70 NPHS2 stomatin family member, podocin Homo sapiens 21-26 15264208-0 2004 Three siblings with steroid-resistant nephrotic syndrome: new NPHS2 mutations in a Turkish family. Steroids 20-27 NPHS2 stomatin family member, podocin Homo sapiens 62-67 15264208-5 2004 In this report, the cases of 3 siblings with steroid-resistant nephrotic syndrome who carry NPHS2 mutations (R238S and P118L) are presented. Steroids 45-52 NPHS2 stomatin family member, podocin Homo sapiens 92-97 15015071-1 2004 Mutations in the NPHS2 gene encoding podocin are associated with steroid-resistant nephrotic syndrome (SRNS) in childhood. Steroids 65-72 NPHS2 stomatin family member, podocin Homo sapiens 17-22 15015071-1 2004 Mutations in the NPHS2 gene encoding podocin are associated with steroid-resistant nephrotic syndrome (SRNS) in childhood. Steroids 65-72 NPHS2 stomatin family member, podocin Homo sapiens 37-44 15042551-0 2004 Infantile steroid-resistant nephrotic syndrome associated with double homozygous mutations of podocin. Steroids 10-17 NPHS2 stomatin family member, podocin Homo sapiens 94-101 15042551-1 2004 Mutations of NPHS2, ie, the gene coding for podocin, are associated with nephrotic syndrome (NS) in children, with a clinical phenotype characterized by variable age at onset (from 1 to 10 years) and steroid/cyclosporine resistance. Steroids 200-207 NPHS2 stomatin family member, podocin Homo sapiens 13-18 15042551-1 2004 Mutations of NPHS2, ie, the gene coding for podocin, are associated with nephrotic syndrome (NS) in children, with a clinical phenotype characterized by variable age at onset (from 1 to 10 years) and steroid/cyclosporine resistance. Steroids 200-207 NPHS2 stomatin family member, podocin Homo sapiens 44-51 14978175-5 2004 On the basis of a very small number of patients, it was suspected that children with homozygous or compound heterozygous mutations in NPHS2 might exhibit primary steroid resistance and a decreased risk of FSGS recurrence after kidney transplantation. Steroids 162-169 NPHS2 stomatin family member, podocin Homo sapiens 134-139 14978175-11 2004 It was concluded that patients with SRNS with homozygous or compound heterozygous mutations in NPHS2 do not respond to standard steroid treatment and have a reduced risk for recurrence of FSGS in a renal transplant. Steroids 128-135 NPHS2 stomatin family member, podocin Homo sapiens 95-100 14978175-12 2004 Because these findings might affect the treatment plan for childhood SRNS, it might be advisable to perform mutational analysis of NPHS2, if the patient consents, in parallel with the start of the first course of standard steroid therapy. Steroids 222-229 NPHS2 stomatin family member, podocin Homo sapiens 131-136 15327385-1 2004 BACKGROUND: Mutations in NPHS2, encoding podocin, are a prevalent cause of autosomal-recessive steroid-resistant nephrotic syndrome (SRNS). Steroids 95-102 NPHS2 stomatin family member, podocin Homo sapiens 41-48 15253708-0 2004 NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic syndrome and low post-transplant recurrence. Steroids 55-62 NPHS2 stomatin family member, podocin Homo sapiens 0-5 15253708-1 2004 BACKGROUND: Mutations of NPHS2 are causative in familial autosomal-recessive (AR) and sporadic steroid-resistant nephrotic syndrome (SRNS). Steroids 95-102 NPHS2 stomatin family member, podocin Homo sapiens 25-30 14730545-11 2004 Genetic mutations in the NPHS2 gene, which encodes podocin, recently have been shown to be strongly associated with a recessive form of steroid-resistant nephrotic syndrome. Steroids 136-143 NPHS2 stomatin family member, podocin Homo sapiens 51-58 12506137-1 2003 Podocin is identified as a product of the gene mutated in a patient with autosomal recessive steroid-resistant nephrotic syndrome. Steroids 93-100 NPHS2 stomatin family member, podocin Homo sapiens 0-7 14675423-3 2004 Mutations in NPHS2, the gene encoding podocin, are associated with inherited and sporadic cases of steroid-resistant nephrotic syndrome. Steroids 99-106 NPHS2 stomatin family member, podocin Homo sapiens 13-18 14675423-3 2004 Mutations in NPHS2, the gene encoding podocin, are associated with inherited and sporadic cases of steroid-resistant nephrotic syndrome. Steroids 99-106 NPHS2 stomatin family member, podocin Homo sapiens 38-45 14675423-4 2004 Here, we show that brefeldin A induces accumulation of newly synthesized podocin in the endoplasmic reticulum, suggesting that podocin biosynthesis follows the classical secretory pathway, and we study the effect of 12 NPHS2 mutations associated with steroid-resistant nephrotic syndrome on the trafficking of the protein. Steroids 251-258 NPHS2 stomatin family member, podocin Homo sapiens 219-224 14633131-1 2003 BACKGROUND: Mutations of the NPHS2 gene are responsible for autosomal-recessive steroid-resistant nephrotic syndrome. Steroids 80-87 NPHS2 stomatin family member, podocin Homo sapiens 29-34 12707396-3 2003 Single mutations of podocin were found in four steroid-resistant and in four steroid-dependent; five patients had the same mutation (P20L). Steroids 47-54 NPHS2 stomatin family member, podocin Homo sapiens 20-27 12707396-3 2003 Single mutations of podocin were found in four steroid-resistant and in four steroid-dependent; five patients had the same mutation (P20L). Steroids 77-84 NPHS2 stomatin family member, podocin Homo sapiens 20-27 12608558-0 2003 WT-1 and NPHS2 mutation analysis in patients with non-familial steroid-resistant focal-segmental glomerulosclerosis. Steroids 63-70 NPHS2 stomatin family member, podocin Homo sapiens 9-14 14730545-11 2004 Genetic mutations in the NPHS2 gene, which encodes podocin, recently have been shown to be strongly associated with a recessive form of steroid-resistant nephrotic syndrome. Steroids 136-143 NPHS2 stomatin family member, podocin Homo sapiens 25-30 14523896-4 2003 Because the majority of FSGS cases occur as sporadic disease, the recently described mutations in the NPHS2 gene "in approximately 25 percent of cases of apparently sporadic, steroid-resistant FSGS in children" have claimed great interest. Steroids 175-182 NPHS2 stomatin family member, podocin Homo sapiens 102-107 12687458-0 2003 NPHS2 mutations in sporadic steroid-resistant nephrotic syndrome in Japanese children. Steroids 28-35 NPHS2 stomatin family member, podocin Homo sapiens 0-5 12687458-2 2003 NPHS2 mutations are responsible for autosomal recessive familial steroid-resistant nephrotic syndrome (SRNS) with minor glomerular abnormalities or focal segmental glomerulosclerosis (FSGS), which is characterized by early childhood onset (age less than 6 years) and rapid progression to chronic renal insufficiency. Steroids 65-72 NPHS2 stomatin family member, podocin Homo sapiens 0-5 12649741-1 2003 The NPHS2 gene encoding the podocin protein was causally linked to the autosomal recessive type of steroid-resistant nephrotic syndrome. Steroids 99-106 NPHS2 stomatin family member, podocin Homo sapiens 4-9 12649741-1 2003 The NPHS2 gene encoding the podocin protein was causally linked to the autosomal recessive type of steroid-resistant nephrotic syndrome. Steroids 99-106 NPHS2 stomatin family member, podocin Homo sapiens 28-35 12704574-4 2003 Mutations in both podocin gene (NPHS2) alleles lead to a wide range of human disease, from childhood-onset steroid-resistant FSGS and minimal change disease to adult-onset FSGS. Steroids 107-114 NPHS2 stomatin family member, podocin Homo sapiens 18-25 12704574-4 2003 Mutations in both podocin gene (NPHS2) alleles lead to a wide range of human disease, from childhood-onset steroid-resistant FSGS and minimal change disease to adult-onset FSGS. Steroids 107-114 NPHS2 stomatin family member, podocin Homo sapiens 32-37 11805166-0 2002 Novel mutations in NPHS2 detected in both familial and sporadic steroid-resistant nephrotic syndrome. Steroids 64-71 NPHS2 stomatin family member, podocin Homo sapiens 19-24 11786407-1 2002 We recently cloned a novel gene, NPHS2, involved in autosomal recessive steroid-resistant nephrotic syndrome. Steroids 72-79 NPHS2 stomatin family member, podocin Homo sapiens 33-38 11805166-6 2002 Besides better classification of the disease entity, identification of NPHS2 mutations may save some of these patients from unnecessary steroid treatment and also permit the prediction of absence of disease recurrence after kidney transplantation. Steroids 136-143 NPHS2 stomatin family member, podocin Homo sapiens 71-76 11805168-0 2002 Mutations in NPHS2 encoding podocin are a prevalent cause of steroid-resistant nephrotic syndrome among Israeli-Arab children. Steroids 61-68 NPHS2 stomatin family member, podocin Homo sapiens 13-18 11805168-0 2002 Mutations in NPHS2 encoding podocin are a prevalent cause of steroid-resistant nephrotic syndrome among Israeli-Arab children. Steroids 61-68 NPHS2 stomatin family member, podocin Homo sapiens 28-35 11805190-0 2002 Not all in the family: mutations of podocin in sporadic steroid-resistant nephrotic syndrome. Steroids 56-63 NPHS2 stomatin family member, podocin Homo sapiens 36-43 11733557-1 2001 NPHS2 was recently identified as a gene whose mutations cause autosomal recessive steroid-resistant nephrotic syndrome. Steroids 82-89 NPHS2 stomatin family member, podocin Homo sapiens 0-5 11729243-0 2001 Prevalence, genetics, and clinical features of patients carrying podocin mutations in steroid-resistant nonfamilial focal segmental glomerulosclerosis. Steroids 86-93 NPHS2 stomatin family member, podocin Homo sapiens 65-72 11729243-1 2001 Podocin mutations (NPHS2 gene) are responsible for the autosomal recessive form of steroid-resistant nephrotic syndrome. Steroids 83-90 NPHS2 stomatin family member, podocin Homo sapiens 0-7 11729243-1 2001 Podocin mutations (NPHS2 gene) are responsible for the autosomal recessive form of steroid-resistant nephrotic syndrome. Steroids 83-90 NPHS2 stomatin family member, podocin Homo sapiens 19-24 11729243-10 2001 These data demonstrate that podocin mutations in nonfamilial cases of steroid-resistant nephrotic syndrome are frequent and may be due in one case to a founder effect. Steroids 70-77 NPHS2 stomatin family member, podocin Homo sapiens 28-35 10802674-0 2000 Correction to "NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome" Steroids 97-104 NPHS2 stomatin family member, podocin Homo sapiens 15-20 11158229-4 2001 Furthermore, linkage to NPHS2, the gene for autosomal-recessive steroid-resistant INS on chromosome 1, was examined. Steroids 64-71 NPHS2 stomatin family member, podocin Homo sapiens 24-29 10802674-0 2000 Correction to "NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome" Steroids 97-104 NPHS2 stomatin family member, podocin Homo sapiens 54-61