PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12224020-3	2002	We reported that an adenoviral vector containing wt p53 significantly reduced [(3)H]thymidine uptake in melanoma cells containing mutant but not wt p53.	Thymidine	84-93	tumor protein p53	Homo sapiens	52-55	
14695155-2	2003	Importantly, the cytotoxic effects of thymidine deprivation induced by 5-fluorouracil (FUra) combined with leucovorin (LV) was enhanced by IFN-gamma, and the synergism was shown to be dependent on Fas, FUra-induced DNA damage, and independent of p53.	Thymidine	38-47	tumor protein p53	Homo sapiens	246-249	
15647429-10	2005	Chondrocyte [(3)H]thymidine uptake correlated positively with Bcl-2 (r(s) = 0.62, p = 0.009) and correlated inversely with p53 levels (r(s) = -0.55, p = 0.02).	Thymidine	18-27	tumor protein p53	Homo sapiens	123-126	
12782403-5	2003	Pre-transfection of cultured hepatoma cells with p53mt249 resulted in a three to fourfold increase in IGF-IR phosphorylation and downstream mediator IRS-I phosphorylation but, enhanced more than 15-fold after IGF-II treatment, which coincides well with the cell growth and thymidine uptake results.	Thymidine	273-282	tumor protein p53	Homo sapiens	49-52	
9468185-5	1998	p53 gene transfer reduced thymidine incorporation of VSMCs stimulated by platelet-derived growth factor-BB (P<.001).	Thymidine	26-35	tumor protein p53	Homo sapiens	0-3	
10226585-4	1999	Furthermore, 3H-thymidine incorporation in KOSC-3 cells, which display the p53 gene mutation, was inhibited by protons much more than by gamma-rays.	Thymidine	16-25	tumor protein p53	Homo sapiens	75-78	
11980662-9	2002	Both inducible TS expression and the addition of exogenous thymidine (10 microM) blocked p53 and p21 induction by the antifolates but not by 5-FU in the M7TS90 cell line.	Thymidine	59-68	tumor protein p53	Homo sapiens	89-92	
10421546-6	1999	The functional status of p53 in cells was assessed by thymidine and BrdU incorporation following exposure to ionizing radiation (4 Gy).	Thymidine	54-63	tumor protein p53	Homo sapiens	25-28	
9607592-3	1998	The sensitization ratio due to the transfected wt p53 varied from about 2-fold for cisplatin to over 50-fold for thymidine.	Thymidine	113-122	tumor protein p53	Homo sapiens	50-53	
8774641-10	1996	The growth of the Ad5CMV-p53-infected cells was greatly suppressed as detected by both cell count and [3H]thymidine incorporation assay.	Thymidine	106-115	tumor protein p53	Homo sapiens	25-28	
8668331-0	1996	Acute and delayed apoptosis induced by thymidine deprivation correlates with expression of p53 and p53-regulated genes in colon carcinoma cells.	Thymidine	39-48	tumor protein p53	Homo sapiens	91-94	
8668331-0	1996	Acute and delayed apoptosis induced by thymidine deprivation correlates with expression of p53 and p53-regulated genes in colon carcinoma cells.	Thymidine	39-48	tumor protein p53	Homo sapiens	99-102	
9816160-8	1996	Conversely, the hazard increased with the increase of p53-positive cells only for tumors with a [3H]dT LI lower than 7.5%.	Thymidine	100-102	tumor protein p53	Homo sapiens	54-57	
8886839-7	1996	In vitro studies showed that cell growth, as measured by the thymidine incorporation assay, was inhibited in the C4-2, PC-3, and DU145 cells infected with wild-type p53 adenovirus in comparison to control viruses.	Thymidine	61-70	tumor protein p53	Homo sapiens	165-168	
8979269-6	1996	A253-p53 cells could be distinguished from native A253 cells by prolonged doubling times (2-5 fold) and by a marked reduction of [3H]-thymidine uptake.	Thymidine	134-143	tumor protein p53	Homo sapiens	5-8	
9552394-4	1996	In this article we review some of the emerging data that suggests the role of p53 in determining whether the cellular response to dThd deprivation is cytostasis or cytotoxicity (apoptosis).	Thymidine	130-134	tumor protein p53	Homo sapiens	78-81	
18850315-6	2008	Transfection of HUVEC with dominant negative p53 cDNA prevented the progesterone-induced increases in p21 and p27 promoter activity and protein level, decreases in thymidine incorporation, and capillary-like tube formation.	Thymidine	164-173	tumor protein p53	Homo sapiens	45-48	
1873816-7	1991	Immunocytochemical data indicate that prostate carcinoma cells expressing the transfected wild-type p53 gene are growth arrested because they exhibit a reduced level of thymidine incorporation into DNA.	Thymidine	169-178	tumor protein p53	Homo sapiens	100-103	
7560890-3	1995	In breast cancer, we observed a poor correlation (rs = 0.17) between P53 expression and proliferative activity evaluated as [3H]-thymidine ([3H]-dT) labeling index and an independent prognostic relevance of the two variables.	Thymidine	129-138	tumor protein p53	Homo sapiens	69-72	
7560890-3	1995	In breast cancer, we observed a poor correlation (rs = 0.17) between P53 expression and proliferative activity evaluated as [3H]-thymidine ([3H]-dT) labeling index and an independent prognostic relevance of the two variables.	Thymidine	145-147	tumor protein p53	Homo sapiens	69-72	
7560890-7	1995	A weak direct relation between P53 positivity and [3H]-dT incorporation (rs = 0.4) was observed on the overall series of P53+ tumors and was maintained in subgroups defined by several biological and pathological features, except for estrogen receptor-negative tumors.	Thymidine	55-57	tumor protein p53	Homo sapiens	31-34	
7560890-7	1995	A weak direct relation between P53 positivity and [3H]-dT incorporation (rs = 0.4) was observed on the overall series of P53+ tumors and was maintained in subgroups defined by several biological and pathological features, except for estrogen receptor-negative tumors.	Thymidine	55-57	tumor protein p53	Homo sapiens	121-124	
7616356-8	1995	Tumours with p53 gene mutations at exon 5 had a higher median [3H]thymidine labelling index (17 per cent) than those with mutations at exons 6, 7, and 8 (11.8 per cent).	Thymidine	66-75	tumor protein p53	Homo sapiens	13-16	
7627557-2	1995	We have examined potential p53-mediated effects of metabolically labeling cultured mammalian cells with [35S]methionine and [3H]thymidine, methods that are commonly used to study the biochemical properties, synthesis, processing and degradation of proteins and the replication of DNA in proliferating cells.	Thymidine	128-137	tumor protein p53	Homo sapiens	27-30	
1322785-5	1992	Furthermore, the incorporation of thymidine into DNA was reduced in cancer cells expressing the wild-type p53 gene.	Thymidine	34-43	tumor protein p53	Homo sapiens	106-109	
25401976-8	2015	Furthermore, inhibition of Fhit loss-induced DNA damage via thymidine supplementation decreases the TP53 mutation burden in FHIT-low/APOBEC3B-high cells.	Thymidine	60-69	tumor protein p53	Homo sapiens	100-104