PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34644194-5	2022	RESULTS: In specific pathogen-free mice, a decreased mechanical threshold in the hind paw, increased grooming time, increased c-Fos expression level and decreased calcitonin gene-related peptide expression level as well as increased tumor necrosis factor-alpha concentration in the trigeminal nucleus caudalis were observed after nitroglycerin administration compared with saline treatment.	Nitroglycerin	330-343	tumor necrosis factor	Mus musculus	233-260	
34644194-6	2022	However, increased basal sensitivity and higher basal concentrations of TNF-alpha in the trigeminal nucleus caudalis were observed in germ-free and ABX mice, while no significant difference in hyperalgesia was observed between the nitroglycerin group and saline group in germ-free and ABX mice.	Nitroglycerin	231-244	tumor necrosis factor	Mus musculus	72-81	
33323164-9	2020	However, mice given NG had a significant reduction in IL6 and TNFalpha in BAL fluid and no significant differences in CCL2, IL4, IL10, CXCL1, CXCL2, and VEGF.	Nitroglycerin	20-22	tumor necrosis factor	Mus musculus	62-70	
31640402-10	2020	The protein levels of PD-L1 were significantly increased 2 h, 4 h and 6 h after treatment, and PD-1 was significantly increased at 2 h and 6 h. The blockade of PD-1 increased acute nitroglycerin-induced hyperalgesia, and this effect was accompanied by a more significant increase in calcitonin gene-related peptide, IL-1beta, TNF-alpha, IL-6 and IL-18 in the trigeminal ganglia.	Nitroglycerin	181-194	tumor necrosis factor	Mus musculus	326-335	
31378003-4	2020	We observed that antibiotics treatment-prolonged nitroglycerin (NTG)-induced acute migraine-like pain in wild-type (WT) mice and the pain prolongation was completely blocked by genetic deletion of tumor necrosis factor-alpha (TNFalpha) or intra-spinal trigeminal nucleus caudalis (Sp5C) injection of TNFalpha receptor antagonist.	Nitroglycerin	49-62	tumor necrosis factor	Mus musculus	197-224	
31378003-4	2020	We observed that antibiotics treatment-prolonged nitroglycerin (NTG)-induced acute migraine-like pain in wild-type (WT) mice and the pain prolongation was completely blocked by genetic deletion of tumor necrosis factor-alpha (TNFalpha) or intra-spinal trigeminal nucleus caudalis (Sp5C) injection of TNFalpha receptor antagonist.	Nitroglycerin	49-62	tumor necrosis factor	Mus musculus	226-234	
31378003-4	2020	We observed that antibiotics treatment-prolonged nitroglycerin (NTG)-induced acute migraine-like pain in wild-type (WT) mice and the pain prolongation was completely blocked by genetic deletion of tumor necrosis factor-alpha (TNFalpha) or intra-spinal trigeminal nucleus caudalis (Sp5C) injection of TNFalpha receptor antagonist.	Nitroglycerin	64-67	tumor necrosis factor	Mus musculus	197-224	
31378003-4	2020	We observed that antibiotics treatment-prolonged nitroglycerin (NTG)-induced acute migraine-like pain in wild-type (WT) mice and the pain prolongation was completely blocked by genetic deletion of tumor necrosis factor-alpha (TNFalpha) or intra-spinal trigeminal nucleus caudalis (Sp5C) injection of TNFalpha receptor antagonist.	Nitroglycerin	64-67	tumor necrosis factor	Mus musculus	226-234	
31378003-4	2020	We observed that antibiotics treatment-prolonged nitroglycerin (NTG)-induced acute migraine-like pain in wild-type (WT) mice and the pain prolongation was completely blocked by genetic deletion of tumor necrosis factor-alpha (TNFalpha) or intra-spinal trigeminal nucleus caudalis (Sp5C) injection of TNFalpha receptor antagonist.	Nitroglycerin	64-67	tumor necrosis factor	Mus musculus	300-308	
31378003-5	2020	The antibiotics treatment extended NTG-induced TNFalpha upregulation in the Sp5C.	Nitroglycerin	35-38	tumor necrosis factor	Mus musculus	47-55	
23840259-9	2013	In addition, NG enhanced nitric oxide (NO) synthesis and secretions of cytokines including IL-6 and TNF- alpha .	Nitroglycerin	13-15	tumor necrosis factor	Mus musculus	100-110