PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20215428-10	2010	Akt phosphorylation was elevated approximately 15-fold in IGF-1R nondiabetic mice compared with Ntg, and this was maintained in a setting of diabetes.	Nitroglycerin	96-99	thymoma viral proto-oncogene 1	Mus musculus	0-3	
30554658-0	2019	Decreased PKG transcription mediated by PI3K/Akt/FoxO1 pathway is involved in the development of nitroglycerin tolerance.	Nitroglycerin	97-110	thymoma viral proto-oncogene 1	Mus musculus	45-48	
10953024-6	2000	In contrast, endothelium-dependent vasodilatation in response to acetylcholine was attenuated in vessels transduced with dn-Akt, although these vessels showed normal responses to nitroglycerin, an endothelium-independent vasodilator.	Nitroglycerin	179-192	thymoma viral proto-oncogene 1	Mus musculus	124-127	
33128338-6	2021	In Apoe-/- mice, nitroglycerine infusion increased both Akt S-Nitrosylation and infarct size, reduced Akt activity and capillary density, and delayed the recovery of cardiac function in ischaemic hearts, compared with mice infused with vehicle.	Nitroglycerin	17-31	thymoma viral proto-oncogene 1	Mus musculus	56-59	
33128338-6	2021	In Apoe-/- mice, nitroglycerine infusion increased both Akt S-Nitrosylation and infarct size, reduced Akt activity and capillary density, and delayed the recovery of cardiac function in ischaemic hearts, compared with mice infused with vehicle.	Nitroglycerin	17-31	thymoma viral proto-oncogene 1	Mus musculus	102-105	
33128338-7	2021	Importantly, these in vivo effects of nitroglycerine in Apoe-/- mice were remarkably prevented by adenovirus-mediated enforced expression of Akt-C296/344A mutant.	Nitroglycerin	38-52	thymoma viral proto-oncogene 1	Mus musculus	141-144	
30554658-2	2019	The present study is to determine whether PI3K/Akt pathway in vascular smooth muscle cells is involved in nitroglycerin (NTG) tolerance and the underlying mechanism.	Nitroglycerin	106-119	thymoma viral proto-oncogene 1	Mus musculus	47-50	
30554658-2	2019	The present study is to determine whether PI3K/Akt pathway in vascular smooth muscle cells is involved in nitroglycerin (NTG) tolerance and the underlying mechanism.	Nitroglycerin	121-124	thymoma viral proto-oncogene 1	Mus musculus	47-50	
30554658-15	2019	In conclusion, the present study suggests that PI3K/Akt in vascular smooth muscle is involved in the development of NTG tolerance via inhibiting PKG transcription and the effect is mediated by FoxO1.	Nitroglycerin	116-119	thymoma viral proto-oncogene 1	Mus musculus	52-55