PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24824125-1	2014	OBJECTIVE: To study the role of tumor necrosis factor-alpha (TNFalpha) in the anti-replication effects of tetracycline (Tet) on hepatitis B virus (HBV).	tet	120-123	tumor necrosis factor	Homo sapiens	61-69	
27880838-4	2016	To overcome this problem, we developed a TNF-alpha expression test (TET) using primary human monocyte-derived macrophages incubated in the presence or absence of the endotoxin inhibitor, polymyxin B sulfate, and found that this assay, performed with non-cytotoxic doses of the GBM samples, enabled unequivocal detection of endotoxin with a sensitivity that is comparable to the LAL assay.	tet	68-71	tumor necrosis factor	Homo sapiens	41-50	
24824125-6	2014	TNFalpha expression from the vector was induced by exposure to various concentrations of Tet and measured by enzyme-linked immunosorbent assay to determine the appropriate Tet concentration for experimentation.	tet	89-92	tumor necrosis factor	Homo sapiens	0-8	
24824125-6	2014	TNFalpha expression from the vector was induced by exposure to various concentrations of Tet and measured by enzyme-linked immunosorbent assay to determine the appropriate Tet concentration for experimentation.	tet	172-175	tumor necrosis factor	Homo sapiens	0-8	
24824125-7	2014	To investigate whether Tet inhibits TNFalpha expression as a mechanism of its anti-replication activity against HBV, the HepG2.2.15 cell line stably transfected with pVITRO3-TOTR-TNFalpha was used as an HBV replication model.	tet	23-26	tumor necrosis factor	Homo sapiens	36-44	
24824125-10	2014	RESULTS: The TNFalpha expression from the newly constructed pVITRO3-TOTR-TNFalpha vector was Tet-controllable in the eukaryotic cells examined.	tet	93-96	tumor necrosis factor	Homo sapiens	13-21	
24824125-10	2014	RESULTS: The TNFalpha expression from the newly constructed pVITRO3-TOTR-TNFalpha vector was Tet-controllable in the eukaryotic cells examined.	tet	93-96	tumor necrosis factor	Homo sapiens	73-81	
24824125-17	2014	CONCLUSION: A Tet-dependent regulatory fragment double-expressing TNFalpha single vector system was constructed successfully, achieving controllable TNFalpha expression in both transiently transfected eukaryotic cells and stable cell lines.	tet	14-17	tumor necrosis factor	Homo sapiens	66-74	
24824125-17	2014	CONCLUSION: A Tet-dependent regulatory fragment double-expressing TNFalpha single vector system was constructed successfully, achieving controllable TNFalpha expression in both transiently transfected eukaryotic cells and stable cell lines.	tet	14-17	tumor necrosis factor	Homo sapiens	149-157	
24824125-18	2014	In this HBV cell model system, Tet-induced overexpression of human TNFalpha inhibited HBV DNA replication and reduced HBsAg and HBeAg expression.	tet	31-34	tumor necrosis factor	Homo sapiens	67-75	
18498042-4	2008	We found that TET decreased the release of NO, TNF-alpha, IL-6 and IL-1beta in LPS-activated astrocytes.	tet	14-17	tumor necrosis factor	Homo sapiens	47-56	
30824537-5	2019	In contrast, prolonged TNFalpha treatment (several days) induced DNA demethylation at the promoter and a CpG island in the IL-32 gene in a TET (ten-eleven translocation) family enzyme- and NF-kappaB-dependent manner.	tet	139-142	tumor necrosis factor	Homo sapiens	23-31	
30428756-7	2018	Furthermore, co-incubation with Tet significantly down-regulated HaCaT cell production of tumour necrosis factor (TNF)-alpha, IL-1beta, IL-6, IL-20 and chemokine (C-C motif) ligand 20 (CCL20) induced by IL-22.	tet	32-35	tumor necrosis factor	Homo sapiens	90-124