PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35586434-4	2022	Recently, a novel cytosine-based inhibitor of TET, Bobcat339, was reported to have mid-muM inhibitory activity against TET1 and TET2.	tet	46-49	tet methylcytosine dioxygenase 1	Homo sapiens	119-123	
26013976-9	2015	Among TET family members, the expression of TET1 was exclusively induced by hypoxia via HIF-1alpha-independent pathways in SSc fibroblasts, but not in normal fibroblasts.	tet	6-9	tet methylcytosine dioxygenase 1	Homo sapiens	44-48	
29175454-7	2018	To gain an understanding into how iAs might impact TET expression, we found that iAs inhibits the binding of CTCF at the proximal, weak CTCF binding sites of the TET1 and TET2 gene promoters and enhances CTCF binding at the stronger distal binding site.	tet	51-54	tet methylcytosine dioxygenase 1	Homo sapiens	162-166	
33694104-4	2021	In humans, there are three TET paralogs with tissue-specific expression, namely TET1, TET2, and TET3.	tet	27-30	tet methylcytosine dioxygenase 1	Homo sapiens	80-84	
32979201-2	2021	5-Hydroxymethylcytosine (5hmC) modifications are generated by the Ten-eleven-translocation (TET) family of enzymes, TET 1, 2, and 3, through the oxidation of methylated cytosines (5mC).	tet	92-95	tet methylcytosine dioxygenase 1	Homo sapiens	116-131	
31033072-5	2019	Among the three TET genes, TET1 and TET2 expression levels have frequently been shown to be low in hepatocellular carcinoma (HCC) tissues and received most attention.	tet	16-19	tet methylcytosine dioxygenase 1	Homo sapiens	27-31	
32397801-5	2020	When the activity of TET enzymes was inhibited by dimethyloxalylglycine (DMOG) treatment, a dioxygenase inhibitor, to investigate the role of TET1 while eliminating the potential compensatory activation of TET3, reduced level of pluripotency genes including NANOG and ESRRB, and increased level of DNA methylation in the NANOG promoter was detected.	tet	21-24	tet methylcytosine dioxygenase 1	Homo sapiens	142-146	
31055566-3	2019	The TET family includes three members: TET1, TET2, and TET3.	tet	4-7	tet methylcytosine dioxygenase 1	Homo sapiens	39-43	
26378518-2	2015	The TET family includes TET1, TET2 and TET3 members in mammals.	tet	4-7	tet methylcytosine dioxygenase 1	Homo sapiens	24-28	
26633372-3	2015	Three TET paralogs have been identified (TET1, TET2, and TET3) in humans.	tet	6-9	tet methylcytosine dioxygenase 1	Homo sapiens	41-45	
27523618-6	2016	Notably, we demonstrate that MCPIP1 reduces TET (TET1/TET2/TET3) levels and then decreases 5-hydroxymethylcytosine levels.	tet	44-47	tet methylcytosine dioxygenase 1	Homo sapiens	49-53	
23222540-1	2013	Ten eleven translocation (TET) enzymes, including TET1, TET2 and TET3, convert 5-methylcytosine to 5-hydroxymethylcytosine and regulate gene transcription.	tet	26-29	tet methylcytosine dioxygenase 1	Homo sapiens	50-54	
23697932-5	2013	For example, CFP1 (CxxC finger protein 1), MLL (mixed lineage leukaemia protein), KDM (lysine demethylase) 2A and KDM2B regulate lysine methylation on histone tails, whereas TET (ten-eleven translocation) 1 and TET3 hydroxylate methylated cytosine bases.	tet	174-177	tet methylcytosine dioxygenase 1	Homo sapiens	179-206	
23730200-4	2012	These new modifications, putative intermediates in a pathway to erase DNA methylation marks, are catalyzed by the ten-eleven translocation (Tet) proteins, specifically by Tet1 and Tet2 in ES cells.	tet	140-143	tet methylcytosine dioxygenase 1	Homo sapiens	171-175