PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21617369-3 2011 TET, Jumonji-family histone demethylases, and prolyl hydroxylase, a repressor of HIF1alpha under high oxygen conditions, all require alpha ketoglutarate (alpha-KG) as cofactors for their activation. tet 0-3 hypoxia inducible factor 1 subunit alpha Homo sapiens 81-90 29163682-5 2017 A chemical inducer of HIF-1alpha, CoCl2, also increases the expression of TET enzymes. tet 74-77 hypoxia inducible factor 1 subunit alpha Homo sapiens 22-32 29163682-7 2017 These results indicate that hypoxia controls DNA methylation through HIF-1alpha-mediated TET enzyme regulation in HepG2 cells. tet 89-92 hypoxia inducible factor 1 subunit alpha Homo sapiens 69-79 26013976-4 2015 The effects of hypoxia and siRNA specific to HIF-1alpha on TET expression were also examined. tet 59-62 hypoxia inducible factor 1 subunit alpha Homo sapiens 45-55 26013976-9 2015 Among TET family members, the expression of TET1 was exclusively induced by hypoxia via HIF-1alpha-independent pathways in SSc fibroblasts, but not in normal fibroblasts. tet 6-9 hypoxia inducible factor 1 subunit alpha Homo sapiens 88-98 28601635-3 2017 Many malignancies, including melanoma, also aberrantly overexpress the oncogenic hypoxia inducible factor-1alpha (HIF-1alpha) transcription factor, however the association between HIF-1alpha and TET enzyme expression is largely uninvestigated. tet 195-198 hypoxia inducible factor 1 subunit alpha Homo sapiens 81-112 28601635-3 2017 Many malignancies, including melanoma, also aberrantly overexpress the oncogenic hypoxia inducible factor-1alpha (HIF-1alpha) transcription factor, however the association between HIF-1alpha and TET enzyme expression is largely uninvestigated. tet 195-198 hypoxia inducible factor 1 subunit alpha Homo sapiens 114-124 28601635-3 2017 Many malignancies, including melanoma, also aberrantly overexpress the oncogenic hypoxia inducible factor-1alpha (HIF-1alpha) transcription factor, however the association between HIF-1alpha and TET enzyme expression is largely uninvestigated. tet 195-198 hypoxia inducible factor 1 subunit alpha Homo sapiens 180-190 28601635-7 2017 Our data provides novel evidence that HIF-1alpha is involved in regulating TET expression and 5 hmC status of malignant cells. tet 75-78 hypoxia inducible factor 1 subunit alpha Homo sapiens 38-48