PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35429141-13 2022 CONCLUSION: Mubritinib can upregulate intracellular ROS concentration and cell apoptosis, inhibit the PI3K signaling pathway and interfere with the function of mitochondria, thus reducing cell proliferation and increasing ROS induced apoptosis by reducing the activation of Nrf2 by PI3K. TAK-165 12-22 nuclear factor, erythroid derived 2, like 2 Mus musculus 274-278