PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8763993-14	1996	TNF cytolysis was blocked by dexamethasone, an inhibitor of PLA2 activity, and by nordihydroquaiaretic acid, which inhibits the metabolism of AA to the leukotrienes.	Leukotrienes	152-164	tumor necrosis factor	Mus musculus	0-3	
16436205-5	2006	Nonetheless astrocytes cultured from G93A-SOD1 (but not wild-type human SOD1-expressing) transgenic mouse pups demonstrated a significant elevation in either the basal or the tumor necrosis alpha (TNFalpha)-stimulated levels of proinflammatory eicosanoids prostaglandin E2 (PGE2) and leukotriene B4 (LTB4); inducible nitric oxide synthase (iNOS) and *NO (indexed by nitrite release into the culture medium); and protein carbonyl products.	Leukotrienes	284-295	tumor necrosis factor	Mus musculus	197-205	
15060681-3	2004	Prostaglandins and leukotrienes are thought to play opposing roles in regulating TNF production by monocytes and macrophages.	Leukotrienes	19-31	tumor necrosis factor	Mus musculus	81-84	
8473568-2	1993	It is proposed that cycloheximide acts as an inhibitor of the endotoxin-induced activation of phospholipase A2, thereby inhibiting the synthesis of leukotrienes which is now known to be a prerequisite for tumour necrosis factor-alpha (TNF) biosynthesis, the latter cytokine being regarded as the terminal mediator of the fatal D-galactosamine and endotoxin-induced syndrome.	Leukotrienes	148-160	tumor necrosis factor	Mus musculus	235-238	
1335420-2	1992	Tumor necrosis factor-alpha is known to induce inflammatory mediators such as leukotrienes and prostanoids.	Leukotrienes	78-90	tumor necrosis factor	Mus musculus	0-27	
3131072-11	1987	A possible mechanism of action of TNF is the release and metabolism of polyunsaturated fatty acids, which would explain the synthesis of prostaglandins and leukotrienes by many cell types after TNF treatment.	Leukotrienes	156-168	tumor necrosis factor	Mus musculus	34-37	
3131072-11	1987	A possible mechanism of action of TNF is the release and metabolism of polyunsaturated fatty acids, which would explain the synthesis of prostaglandins and leukotrienes by many cell types after TNF treatment.	Leukotrienes	156-168	tumor necrosis factor	Mus musculus	194-197