PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16165096-1 2005 A key enzyme for leukotriene biosynthesis is 5-lipoxygenase (5-LO), which we found is exported from the nucleus when p38 MAPK is activated. Leukotrienes 17-28 mitogen-activated protein kinase 14 Homo sapiens 117-120 17979994-0 2008 A mechanism of benefit of soy genistein in asthma: inhibition of eosinophil p38-dependent leukotriene synthesis. Leukotrienes 90-101 mitogen-activated protein kinase 14 Homo sapiens 76-79 17504658-4 2007 Exercise increases the distribution of leukotrienes and influences the leukotriene transcription pathway; it could be shown that the genes ALOX5 and ALOX5AP encoding for 5-lipooxygenase (5-LO) and 5-lipoxygenase-activating protein (FLAP) as well as activators for 5-LO, p38 -mitogen-activated protein kinase (MAPK), and others, are enhanced after exercise in healthy subjects. Leukotrienes 39-51 mitogen-activated protein kinase 14 Homo sapiens 270-273 17504658-4 2007 Exercise increases the distribution of leukotrienes and influences the leukotriene transcription pathway; it could be shown that the genes ALOX5 and ALOX5AP encoding for 5-lipooxygenase (5-LO) and 5-lipoxygenase-activating protein (FLAP) as well as activators for 5-LO, p38 -mitogen-activated protein kinase (MAPK), and others, are enhanced after exercise in healthy subjects. Leukotrienes 39-50 mitogen-activated protein kinase 14 Homo sapiens 270-273 35392553-7 2022 The reduction of p38 and ERK phosphorylation is associated with a decrease in cPLA2alpha phosphorylation and attenuated leukotriene production. Leukotrienes 120-131 mitogen-activated protein kinase 14 Homo sapiens 17-20 11698504-0 2001 p38 MAP kinase mediates stress-induced leukotriene synthesis in a human B-lymphocyte cell line. Leukotrienes 39-50 mitogen-activated protein kinase 14 Homo sapiens 0-3 11698504-6 2001 The p38 MAP kinase inhibitor SB203580 abolished stress-induced leukotriene synthesis in B cells, without inhibition of 5-LO catalytic activity in cell-free systems. Leukotrienes 63-74 mitogen-activated protein kinase 14 Homo sapiens 4-7 11698504-7 2001 Our results indicate that p38 MAP kinase activation by cell stress is required for efficient leukotriene synthesis in B-lymphocytes. Leukotrienes 93-104 mitogen-activated protein kinase 14 Homo sapiens 26-29 11844797-1 2002 We demonstrated previously that 5-lipoxygenase (5-LO), a key enzyme in leukotriene biosynthesis, can be phosphorylated by p38 MAPK-regulated MAPKAP kinases (MKs). Leukotrienes 71-82 mitogen-activated protein kinase 14 Homo sapiens 122-125