PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10422663-11 1999 Our results support the conclusion that TNF alpha is a mediator of CG-induced inflammatory incapacitation, and is able to induce the further release of kinins and leukotrienes, which is suggested to have an important role in the maintenance of long-lasting nociceptive response. Leukotrienes 163-175 tumor necrosis factor Rattus norvegicus 40-49 8111596-1 1994 TNF-alpha:leukotriene axis. Leukotrienes 10-21 tumor necrosis factor Rattus norvegicus 0-9 1329867-2 1992 Since 5-lipoxygenase metabolites have been shown to possess proinflammatory effects and to promote the release of cytokines such as tumor necrosis factor-alpha (TNF-alpha) from mononuclear phagocytes, we determined leukotriene secretion from silica-exposed AM. Leukotrienes 215-226 tumor necrosis factor Rattus norvegicus 161-170 1650523-4 1991 Injection of zymosan into the airpouch caused a time-dependent stimulation of TNF production which preceded leukotriene generation by at least 30 minutes. Leukotrienes 108-119 tumor necrosis factor Rattus norvegicus 78-81 2851448-0 1988 Tumor necrosis factor alpha stimulates leukotriene production in vivo. Leukotrienes 39-50 tumor necrosis factor Rattus norvegicus 0-27 2851448-3 1988 TNF as well as LPS stimulated the arachidonate cascade leading to the synthesis of leukotrienes (LT) in vivo. Leukotrienes 83-95 tumor necrosis factor Rattus norvegicus 0-3 2851448-6 1988 LT production elicited by TNF was similar to that evoked by infusion of LPS. Leukotrienes 0-2 tumor necrosis factor Rattus norvegicus 26-29 2827923-0 1987 Recombinant human tumour necrosis factor (rTNF)2 enhances leukotriene biosynthesis in neutrophils and eosinophils stimulated with the Ca2+ ionophore A23187. Leukotrienes 58-69 tumor necrosis factor Rattus norvegicus 42-46 2827923-5 1987 Increased leukotriene production was attributed to the induction of fatty acid hydrolase and/or 5-lipoxygenase activities on the basis of the increment in the total counts released after 3H-arachidonic acid labelling of neutrophils pretreated with rTNF as compared to control medium. Leukotrienes 10-21 tumor necrosis factor Rattus norvegicus 248-252