PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33671954-4 2021 Suppression of VEGF-A by directly targeting the leukotriene B4 (LTB4) receptor (BLT1) pathway indicates a connection between leukotrienes (LTs), which have prominent roles in initiating and propagating inflammatory responses, and VEGF-A in retinal inflammatory diseases. Leukotrienes 125-137 leukotriene B4 receptor Homo sapiens 48-78 33671954-4 2021 Suppression of VEGF-A by directly targeting the leukotriene B4 (LTB4) receptor (BLT1) pathway indicates a connection between leukotrienes (LTs), which have prominent roles in initiating and propagating inflammatory responses, and VEGF-A in retinal inflammatory diseases. Leukotrienes 125-137 leukotriene B4 receptor Homo sapiens 80-84 33671954-4 2021 Suppression of VEGF-A by directly targeting the leukotriene B4 (LTB4) receptor (BLT1) pathway indicates a connection between leukotrienes (LTs), which have prominent roles in initiating and propagating inflammatory responses, and VEGF-A in retinal inflammatory diseases. Leukotrienes 139-142 leukotriene B4 receptor Homo sapiens 48-78 33671954-4 2021 Suppression of VEGF-A by directly targeting the leukotriene B4 (LTB4) receptor (BLT1) pathway indicates a connection between leukotrienes (LTs), which have prominent roles in initiating and propagating inflammatory responses, and VEGF-A in retinal inflammatory diseases. Leukotrienes 139-142 leukotriene B4 receptor Homo sapiens 80-84 31357612-5 2019 Moreover, the LTB4-leukotriene B4 receptor 1 (BLT1) axis participates in the acute kidney injury via mediating the recruitment of renal neutrophils. Leukotrienes 19-30 leukotriene B4 receptor Homo sapiens 46-50 32392205-1 2020 The leukotriene B4 receptors BLT1 and BLT2 are promising targets for the treatment of allergic and inflammatory diseases. Leukotrienes 4-15 leukotriene B4 receptor Homo sapiens 29-33 29042028-0 2017 Importance of the leukotriene B4-BLT1 and LTB4-BLT2 pathways in asthma. Leukotrienes 18-29 leukotriene B4 receptor Homo sapiens 33-37 30204485-2 2018 While DHA seems to inhibit growth and prevent carcinogenic processes, stimulation of leukotriene B4 receptors BLT1 and BLT2 by several eicosanoids derived from AA plays an important role in mediating cisplatin resistance in ovarian cancer cells. Leukotrienes 85-96 leukotriene B4 receptor Homo sapiens 110-114 29042029-5 2017 Many studies have implicated that blockade of leukotriene B4 (LTB4) and its high affinity receptor BLT1 dramatically suppress arthritis in animal models. Leukotrienes 46-57 leukotriene B4 receptor Homo sapiens 99-103 17394438-1 2007 The 5-Lipoxygenase pathway results in the formation of leukotrienes, including leukotriene B(4) (LTB(4)), 5-oxo-6E,8Z,11Z,14Z-eicosatetranoic acid and the cysteinyl leukotrienes (LTC(4), LTD(4) and LTE(4)) and activates all four leukotriene receptors, BLT1, BLT2, cysLT(1) and cysLT(2). Leukotrienes 55-67 leukotriene B4 receptor Homo sapiens 252-256 27475906-1 2016 BACKGROUND: Leukotriene B4 (LTB4R and LTB4R2) and cysteinyl leukotriene receptors (CYSLTR1 and CYSLTR2) contribute to malignant cell transformation. Leukotrienes 12-23 leukotriene B4 receptor Homo sapiens 28-33 26696753-1 2015 Accumulating evidence indicates that leukotriene B4 (LTB4) via its receptors BLT1 and/or BLT2 (BLTRs) could have an important role in regulating infection, tumour progression, inflammation, and autoimmune diseases. Leukotrienes 37-48 leukotriene B4 receptor Homo sapiens 77-81 21307335-0 2011 Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1. Leukotrienes 0-11 leukotriene B4 receptor Homo sapiens 84-88 16293697-0 2005 Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Leukotrienes 0-11 leukotriene B4 receptor Homo sapiens 53-57 16624877-1 2006 Leukotriene (LT) B4 is a powerful chemotactic and immune modulating agent that signals via two receptors denoted BLT1 and BLT2. Leukotrienes 0-11 leukotriene B4 receptor Homo sapiens 113-117 16493075-1 2006 Studies in both humans and rodents have suggested that CD8+ T cells contribute to the development of airway hyperresponsiveness (AHR) and that leukotriene B4 (LTB4) is involved in the chemotaxis of effector CD8+ T cells (T(EFF)) to the lung by virtue of their expression of BLT1, the receptor for LTB4. Leukotrienes 143-154 leukotriene B4 receptor Homo sapiens 274-278 16179368-0 2006 The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans. Leukotrienes 4-15 leukotriene B4 receptor Homo sapiens 50-54 12902512-2 2003 The leukotrienes (LT) and CXC chemokines (CXC) and their receptors (BLT1/BLT2 and CXCR1/CXCR2) are all known to play roles in these responses. Leukotrienes 4-16 leukotriene B4 receptor Homo sapiens 68-72 15565232-0 2004 Preparation of 2- and 4-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans having potent antagonistic activity against human leukotriene B4 BLT1 and/or BLT2 receptors. Leukotrienes 132-143 leukotriene B4 receptor Homo sapiens 147-151 10913346-5 2000 Studies of intracellular calcium flow of transfected HeLa cells exposed to various leukotrienes showed that also the novel BLTR-like receptor can be activated by leukotriene B(4), and it is therefore tentatively named BLTR2. Leukotrienes 83-95 leukotriene B4 receptor Homo sapiens 123-127 12721292-3 2003 BV released from Sf9 cells infected with a recombinant baculovirus coding for human leukotriene B4 receptor (BLT1) cDNA exhibited a high level of BLT1 expression (27.3 pmol/mg of protein) and specific [3H]leukotriene B4 binding activity (Kd = 3.67 nm). Leukotrienes 84-95 leukotriene B4 receptor Homo sapiens 109-113 12721292-3 2003 BV released from Sf9 cells infected with a recombinant baculovirus coding for human leukotriene B4 receptor (BLT1) cDNA exhibited a high level of BLT1 expression (27.3 pmol/mg of protein) and specific [3H]leukotriene B4 binding activity (Kd = 3.67 nm). Leukotrienes 84-95 leukotriene B4 receptor Homo sapiens 146-150 10085095-0 1999 Leukotriene binding, signaling, and analysis of HIV coreceptor function in mouse and human leukotriene B4 receptor-transfected cells. Leukotrienes 0-11 leukotriene B4 receptor Homo sapiens 91-114 35461365-6 2022 ALOX5 mediates resistance to daunorubicin (DNR) and promotes AML cell survival and maintenance through its leukotriene (LT) synthetic capacity, specifically via modulating the synthesis of LTB4 and its binding to LTB receptor (BLTR). Leukotrienes 107-118 leukotriene B4 receptor Homo sapiens 227-231 35461365-6 2022 ALOX5 mediates resistance to daunorubicin (DNR) and promotes AML cell survival and maintenance through its leukotriene (LT) synthetic capacity, specifically via modulating the synthesis of LTB4 and its binding to LTB receptor (BLTR). Leukotrienes 120-122 leukotriene B4 receptor Homo sapiens 227-231