PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19020730-9	2008	TAE226 inhibited the expression of mTOR, Akt, p70S6K and S6 as well as the phosphorylation of mTOR (Ser2448), Akt (Ser473), p70S6K (Thr389) and S6 (Ser240/244).	TAE226	0-6	AKT serine/threonine kinase 1	Homo sapiens	41-44	
22766511-7	2012	In addition, TAE226 inhibited the expression of phospho-FAK Tyr(397) and phospho AKT Ser(473), resulting in caspase-mediated apoptosis.	TAE226	13-19	AKT serine/threonine kinase 1	Homo sapiens	81-84	
19729215-6	2009	Intriguingly, TAE226 only significantly radiosensitized 3D HNSCC cell cultures accompanied by a pronounced dephosphorylation of FAK, Akt and ERK1/2.	TAE226	14-20	AKT serine/threonine kinase 1	Homo sapiens	133-136	
19020730-9	2008	TAE226 inhibited the expression of mTOR, Akt, p70S6K and S6 as well as the phosphorylation of mTOR (Ser2448), Akt (Ser473), p70S6K (Thr389) and S6 (Ser240/244).	TAE226	0-6	AKT serine/threonine kinase 1	Homo sapiens	110-113	
18628478-9	2008	The activities of FAK, IGF-IR, and AKT were suppressed by TAE226 and subsequent dephosphorylation of BAD at Ser(136) occurred, resulting in caspase-mediated apoptosis.	TAE226	58-64	AKT serine/threonine kinase 1	Homo sapiens	35-38	
17219439-8	2007	TAE226 inhibited the phosphorylation of FAK as well as the downstream effectors AKT, extracellular signal-related kinase, and S6 ribosomal protein in multiple glioma cell lines.	TAE226	0-6	AKT serine/threonine kinase 1	Homo sapiens	80-83	
17431114-6	2007	TAE226 also inhibited IGF-I-induced phosphorylation of IGF-IR and activity of its downstream target genes such as MAPK and Akt.	TAE226	0-6	AKT serine/threonine kinase 1	Homo sapiens	123-126