PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31215459-0 2019 Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo tumor models. TAE226 64-70 insulin-like growth factor I receptor Mus musculus 40-46 31215459-7 2019 In the MIA PaCa-2 model, TAE226 inhibited phosphorylation of Y397-FAK and phosphorylation of S473-Akt as IGF-1R signaling in the cell culture in vitro and the tumor in mice. TAE226 25-31 insulin-like growth factor I receptor Mus musculus 105-111 27531475-0 2016 [Therapeutic effect of IGF-1R-targeting inhibitor (TAE226) on malignant pleural effusion in nude mice]. TAE226 51-57 insulin-like growth factor I receptor Mus musculus 23-29 27531475-1 2016 OBJECTIVE: To study the therapeutic effect of IGF-1R inhibitor TAE226 on malignant pleural effusion (MPE) in nude mice. TAE226 63-69 insulin-like growth factor I receptor Mus musculus 46-52 26090892-1 2015 TAE226, a bis-anilino pyrimidine compound, has been developed as an inhibitor of focal adhesion kinase (FAK) and insulin-like growth factor-I receptor (IGF-IR). TAE226 0-6 insulin-like growth factor I receptor Mus musculus 113-150 26090892-1 2015 TAE226, a bis-anilino pyrimidine compound, has been developed as an inhibitor of focal adhesion kinase (FAK) and insulin-like growth factor-I receptor (IGF-IR). TAE226 0-6 insulin-like growth factor I receptor Mus musculus 152-158