PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17721032-2 2007 Earlier studies on apolipoprotein E-knockout mice (apoE-KO) mice suggested adverse effects of Chlamydia pneumoniae infection on the endothelial vasomotor responses of aortas to the muscarinic agonist methacholine. Methacholine Chloride 200-212 apolipoprotein E Mus musculus 51-55 17626122-8 2007 With both hypoxic and methacholine challenges, arteries from ApoE and LDLR strains demonstrated an increased production of both 12(S)- and 15(S)-hydroxyeicosatetraenoic acid, end products of arachidonic acid metabolism via 12/15-lipoxygenase, a response that was not present in C57 controls. Methacholine Chloride 22-34 apolipoprotein E Mus musculus 61-65