PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9768575-9	1998	Allergen-stimulated IL-5 production in coculture with both AMs and PMNs inversely correlated with both baseline FEV1 percent predicted and PD20 methacholine in atopic asthmatic subjects (P &lt; .05, P &lt; .01, or P &lt; .001).	Methacholine Chloride	144-156	interleukin 5	Homo sapiens	20-24	
9445301-1	1998	In order to investigate the role of interleukin-5 (IL-5) in airway hyperreactivity and eosinophilia, we observed the effect of inhaled recombinant human IL-5 on airway responsiveness to methacholine and cell populations in induced sputum in eight patients with allergic bronchial asthma using a placebo-controlled study design.	Methacholine Chloride	186-198	interleukin 5	Homo sapiens	153-157	
9445301-4	1998	In contrast, after IL-5 inhalation, methacholine PC20 fell from baseline (0.90 +/- 166 mg/ml) to 0.32 +/- 1.63 mg/ml (p &lt; 0.01) at 24 h, and to 0.55 +/- 1.49 mg/ml (p &lt; 0.05) at 48 h. Accompanying this increased airway sensitivity was a significant eosinophilia and elevated concentrations of ECP in induced sputum.	Methacholine Chloride	36-48	interleukin 5	Homo sapiens	19-23	
8970344-5	1996	Furthermore, seasonal changes in symptom score, FEV1 % predicted, and PD20 methacholine correlated with seasonal elevated production of IL-5 by PBMC in the asthmatic group (r = 0.862, -0.679, and -0.620; p &lt; 0.01, 0.02, and 0.05, respectively).	Methacholine Chloride	75-87	interleukin 5	Homo sapiens	136-140	
17537187-3	2008	METHODS: We assessed the number of eosinophil and the levels of eosinophil cationic protein (ECP) and interleukin (IL)-5 in induced sputum and bronchial responsiveness to methacholine in 76 patients with totally controlled asthma in comparison with 30 current untreated asthmatics and 20 healthy subjects.	Methacholine Chloride	171-183	interleukin 5	Homo sapiens	102-120	
17537187-6	2008	In the total control group, number of eosinophil and the levels of ECP and IL-5 in induced sputum of patients with negative methacholine challenge test were significantly lower than those in subjects with positive methacholine challenge test (p &lt; 0.001), whereas sputum number of eosinophil and the levels of ECP and IL-5 in patients with negative methacholine challenge test and those of healthy subjects were similar (p &gt; 0.05).	Methacholine Chloride	124-136	interleukin 5	Homo sapiens	75-79