PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6322302-3 1984 The addition of forskolin to resting or methacholine-contracted muscles resulted in an increase in myosin light chain kinase phosphorylation of myosin light chain kinase is one of the reactions in the process by which cyclic adenosine monophosphate causes relaxation of smooth muscle. Methacholine Chloride 40-52 myosin heavy chain 14 Homo sapiens 99-105 2745270-2 1989 Methacholine (10(-6) M) induced rapid increases in isometric force and in phosphorylation of the 20,000-Da myosin light chain. Methacholine Chloride 0-12 myosin heavy chain 14 Homo sapiens 107-113 2745270-5 1989 Isoproterenol pretreatment inhibited methacholine-stimulated myosin light chain phosphorylation, shortening velocity, and force during the early stages of force generation. Methacholine Chloride 37-49 myosin heavy chain 14 Homo sapiens 61-67 2745270-7 1989 Isoproterenol pretreatment also caused a rightward non-parallel shift in the methacholine dose-response curves for both isometric tension and myosin light chain phosphorylation. Methacholine Chloride 77-89 myosin heavy chain 14 Homo sapiens 142-148 6776105-3 1980 The myosin phosphate content increased from an initial value of 0.50 to 1.1 mol of phosphate/mol of myosin within 3 min after the addition of 100 microM methacholine to resting tracheal smooth muscle. Methacholine Chloride 153-165 myosin heavy chain 14 Homo sapiens 4-10 6776105-3 1980 The myosin phosphate content increased from an initial value of 0.50 to 1.1 mol of phosphate/mol of myosin within 3 min after the addition of 100 microM methacholine to resting tracheal smooth muscle. Methacholine Chloride 153-165 myosin heavy chain 14 Homo sapiens 100-106 6776105-5 1980 Tracheal smooth muscles relaxed and the phosphate content decreased from 1.2 to 0.50 mol of phosphate/mol of myosin upon the addition of 10 microM atropine to muscles which had been previously contracted with 100 microM methacholine. Methacholine Chloride 220-232 myosin heavy chain 14 Homo sapiens 109-115 6776105-6 1980 Incubating methacholine-contracted muscles in a calcium-free Krebs buffer relaxed tracheal smooth muscles and reduced the phosphate content to 0.2 mol of phosphate/mol of myosin. Methacholine Chloride 11-23 myosin heavy chain 14 Homo sapiens 171-177