PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27939939-4 2017 CD38 deficient mice develop attenuated airway responsiveness to inhaled methacholine following allergen sensitization and challenge compared to wild-type mice indicating its potential role in asthma. Methacholine Chloride 72-84 CD38 antigen Mus musculus 0-4 25594684-4 2015 Mice deficient in Cd38 exhibit reduced airway responsiveness to inhaled methacholine relative to the response in wild-type mice. Methacholine Chloride 72-84 CD38 antigen Mus musculus 18-22 16891391-6 2006 Changes in methacholine-induced R(L) were significantly greater in the WT than in the CD38KO mice following intranasal IL-13 challenges. Methacholine Chloride 11-23 CD38 antigen Mus musculus 86-90 23213344-6 2012 Airway smooth muscle cells from CD38 knockout mice exhibit attenuated intracellular calcium responses to agonists, and these mice have reduced airway response to inhaled methacholine. Methacholine Chloride 170-182 CD38 antigen Mus musculus 32-36 18931329-4 2009 CD38-deficient and wild-type (WT) mice were sensitized and airway challenged with ovalbumin, and subsequently analyzed regarding their level of airway hyperresponsiveness (AHR) in response to methacholine. Methacholine Chloride 192-204 CD38 antigen Mus musculus 0-4 18514752-6 2008 Furthermore, allergen-associated AHR to methacholine, assessed by lung resistance and dynamic compliance, was completely suppressed in CD38-deficient mice, despite the preservation of airway inflammation. Methacholine Chloride 40-52 CD38 antigen Mus musculus 135-139 15557017-3 2005 The responsiveness to different doses of methacholine, as determined by changes in lung resistance and dynamic compliance, was significantly (P < or = 0.05) lower in cd38(-/-) mice compared with wild-type controls. Methacholine Chloride 41-53 CD38 antigen Mus musculus 169-173