PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8385431-6 1993 MBP, PF4, or cathepsin G induced a 2- to 3-fold increase in airway responsiveness 1 h after instillation, as assessed by the dose of inhaled methacholine required to increase total lung resistance by 100%. Methacholine Chloride 141-153 myelin basic protein Homo sapiens 0-3 7952596-5 1994 Major basic protein caused a significant increase in airway responsiveness to inhaled methacholine. Methacholine Chloride 86-98 myelin basic protein Homo sapiens 0-19 8466137-9 1993 One hour after instillation of MBP there was a significant increase in airway responsiveness to inhaled methacholine, whereas control animals exhibited no increase in airway responsiveness. Methacholine Chloride 104-116 myelin basic protein Homo sapiens 31-34 8466137-12 1993 As with MBP, airway responsiveness to inhaled methacholine increased 1 h after the instillation of either polycation. Methacholine Chloride 46-58 myelin basic protein Homo sapiens 8-11 2010556-2 1991 The results of this study show for the first time that installation of major basic protein (MBP) directly into the trachea of primates results in a significant and dose-related increase in airway responsiveness to inhaled methacholine. Methacholine Chloride 222-234 myelin basic protein Homo sapiens 71-90 2010556-2 1991 The results of this study show for the first time that installation of major basic protein (MBP) directly into the trachea of primates results in a significant and dose-related increase in airway responsiveness to inhaled methacholine. Methacholine Chloride 222-234 myelin basic protein Homo sapiens 92-95