PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7530706-0	1994	Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo.	Methacholine Chloride	59-71	tachykinin precursor 1	Homo sapiens	19-30	
21846969-8	2011	Plasma SP levels correlated with airway sensitivity (threshold dose of methacholine) in the patients with asthmatic cough (r = -0.37, p = 0.005) but not with airway reactivity, cough sensitivity, FEV1 values, or sputum eosinophil and neutrophil counts in either group.	Methacholine Chloride	71-83	tachykinin precursor 1	Homo sapiens	7-9	
7549418-0	1995	The effects of vasoactive intestinal polypeptide and substance P on methacholine-induced sweating and vascular flare in diabetic neuropathy.	Methacholine Chloride	68-80	tachykinin precursor 1	Homo sapiens	53-64	
7549418-6	1995	Injection of VIP or SP reduced methacholine-induced sweating to a similar degree in all groups, except that the reduction was smaller in the non-neuropathic group than in the others (p = 0.028 versus normal subjects, p = 0.014 versus neuropathic diabetic patients).	Methacholine Chloride	31-43	tachykinin precursor 1	Homo sapiens	20-22	
7530706-1	1994	We tested the hypothesis that the inhaled tachykinin substance P (SP) can induce hyperresponsiveness to methacholine in asthmatic subjects in vivo.	Methacholine Chloride	104-116	tachykinin precursor 1	Homo sapiens	66-68	
15707850-0	2005	Relationship between airway responsiveness to neurokinin A and methacholine in asthma.	Methacholine Chloride	63-75	tachykinin precursor 1	Homo sapiens	46-58	
15707850-2	2005	The airway response to NKA in humans closely resembles that of methacholine (M).	Methacholine Chloride	63-75	tachykinin precursor 1	Homo sapiens	23-26	
15707850-10	2005	We have demonstrated a significant relationship between airway responsiveness to NKA and methacholine in asthma.	Methacholine Chloride	89-101	tachykinin precursor 1	Homo sapiens	81-84	
7530706-11	1994	We conclude that 1) a bronchoconstrictive dose of SP, compared with placebo, enhances maximal airway narrowing to methacholine in asthma 24 h after inhalation and 2) tolerance develops to high doses of inhaled methacholine.	Methacholine Chloride	114-126	tachykinin precursor 1	Homo sapiens	50-52	
7530706-11	1994	We conclude that 1) a bronchoconstrictive dose of SP, compared with placebo, enhances maximal airway narrowing to methacholine in asthma 24 h after inhalation and 2) tolerance develops to high doses of inhaled methacholine.	Methacholine Chloride	210-222	tachykinin precursor 1	Homo sapiens	50-52	
7530706-1	1994	We tested the hypothesis that the inhaled tachykinin substance P (SP) can induce hyperresponsiveness to methacholine in asthmatic subjects in vivo.	Methacholine Chloride	104-116	tachykinin precursor 1	Homo sapiens	53-64	
2456227-9	1988	We conclude that SP is absorbed across the nasal mucosa and causes cutaneous vasodilation, that MCH and SP cause a greater rise in NAR in patients suffering from rhinitis than in control subjects, that SP is about 500-fold more potent than MCH in increasing NAR, and that the rise in NAR caused by SP is not mediated by postganglionic parasympathetic mechanisms.	Methacholine Chloride	96-99	tachykinin precursor 1	Homo sapiens	17-19	
2455456-2	1988	In addition, the concentration of serotonin and substance P was measured in nasal secretions following nasal challenge with allergen and methacholine.	Methacholine Chloride	137-149	tachykinin precursor 1	Homo sapiens	48-59	
2443476-2	1987	SP (10(-12) to 10(-4) M) produced dose-dependent increases in the contractile response, and the maximal tension induced by SP was approximately 70% of the response to methacholine.	Methacholine Chloride	167-179	tachykinin precursor 1	Homo sapiens	0-2