PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17499726-0 2007 Differences in binding of (99m)Tc-disintegrins to integrin alphavbeta3 on tumor and vascular cells. Technetium 31-33 integrin subunit alpha V Homo sapiens 50-70 25286251-0 2014 (99m)Tc-3P-RGD2 micro-single-photon emission computed tomography/computed tomography provides a rational basis for integrin alphavbeta3-targeted therapy. Technetium 5-7 integrin subunit alpha V Homo sapiens 115-135 24312152-1 2013 PURPOSE: (99m)Tc-3P-RGD2 is a (99m)Tc-labeled dimeric cyclic RGD peptide that binds to integrin alpha(v)beta3 with high affinity and specificity. Technetium 14-16 integrin subunit alpha V Homo sapiens 87-109 23875883-6 2013 The tumor uptake of (99m)Tc-Galacto-RGD2 was 10.30 +- 1.67, 8.37 +- 2.13, 6.86 +- 1.33, and 5.61 +- 1.52%ID/g at 5, 30, 60, and 120 min p.i., respectively, which was in agreement with high integrin alphavbeta3 expression on glioma cells and neovasculature. Technetium 25-27 integrin subunit alpha V Homo sapiens 189-209 23875883-10 2013 On the basis of results from this study, it was concluded that (99m)Tc-Galacto-RGD2 is an excellent radiotracer for imaging integrin alphavbeta3-positive tumors and related metastases. Technetium 68-70 integrin subunit alpha V Homo sapiens 124-144 23071350-2 2012 The current study was conducted to assess the potential of integrin alpha(v)beta(3) imaging in the detection of RAIR DTC lesions using (99m)Tc-PEG(4)-E[PEG(4)-c(RGDfK)](2) ((99m)Tc-3PRGD2), thus providing a feasible antiangiogenetic therapeutic target. Technetium 140-143 integrin subunit alpha V Homo sapiens 59-83 26109872-9 2015 CONCLUSION: (99m)Tc-labeled T7 and T7-6H can be regarded as promising single-photon emission computed tomography probes for imaging integrin alphavbeta3, and need to be further studied for noninvasive detection of tumors. Technetium 17-19 integrin subunit alpha V Homo sapiens 132-152 20694579-1 2011 PURPOSE: (99m)Tc-3PRGD(2) is a (99m)Tc-labeled dimeric cyclic RGD peptide with increased receptor binding affinity and improved kinetics for in vivo imaging of integrin alpha(v)beta(3) expression in nude mouse model. Technetium 14-16 integrin subunit alpha V Homo sapiens 160-184 19049428-5 2008 It was found that G(3) linkers are particularly useful for increasing integrin alpha(v)beta(3) binding affinity of cyclic RGD dimers and improving the tumor uptake and clearance kinetic of their (99)(m)Tc radiotracers. Technetium 202-204 integrin subunit alpha V Homo sapiens 70-93 18580570-3 2008 The technetium-99m-labeled Arg-Gly-Asp peptide, with high affinity to integrin alphavbeta3, was prepared for biodistribution and gamma-imaging. Technetium 4-18 integrin subunit alpha V Homo sapiens 70-90