PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
4014668-1	1985	Simple and sensitive spectrophotometric and radiochemical procedures are described for the assay of acetyl-CoA:arylamine N-acetyltransferase (NAT; EC 2.3.1.5), which catalyzes the reaction acetyl-CoA + arylamine----N-acetylated arylamine + CoASH.	Acetyl Coenzyme A	100-110	bromodomain containing 2	Homo sapiens	142-145	
26245863-3	2015	Here we investigate functional diversification of NAT enzymes in crop-compromising species of Fusarium and Aspergillus, identifying three groups of homologues: Isoenzymes of the first group are found in all species and catalyse reactions with acetyl-CoA or propionyl-CoA.	Acetyl Coenzyme A	243-253	bromodomain containing 2	Homo sapiens	50-53	
28747958-4	2017	METHODS: To understand the contribution of NAT of MTB and NAT2 of humans in developing INH resistance using in silico approaches, in this study, the wild type (WT) and mutant (MT)-NATs of MTB, and humans, were modeled and docked, with substrates and product (acetyl CoA, INH, and acetyl INH).	Acetyl Coenzyme A	259-269	bromodomain containing 2	Homo sapiens	43-46	
28747958-7	2017	In case of MT-NAT2 from humans, the pattern of score with respect to acetyl CoA and acetyl-INH, was similar to MT-NAT of MTB, but revealed a decrease in INH score.	Acetyl Coenzyme A	69-79	bromodomain containing 2	Homo sapiens	14-17	
11799105-8	2002	Both truncation mutants, however, hydrolyze Ac-CoA even in the absence of arylamine substrate, illustrating that the C-terminal undecapeptide controls hydrolysis of Ac-CoA by NAT from S. typhimurium.	Acetyl Coenzyme A	44-50	bromodomain containing 2	Homo sapiens	175-178	
22776642-5	2012	NAT enzymes have had a role in important metabolic concepts: the identification of acetyl-CoA and endogenous metabolic roles in bacteria and in eukaryotic folate metabolism.	Acetyl Coenzyme A	83-93	bromodomain containing 2	Homo sapiens	0-3	
12595154-1	2003	Arylamine N-acetyltransferase (NAT) enzymes catalyze the addition of an acetyl group from acetyl-CoA to a terminal nitrogen on a suitable substrate such as environmentally relevant compounds and pharmaceuticals.	Acetyl Coenzyme A	90-100	bromodomain containing 2	Homo sapiens	31-34	
11799105-8	2002	Both truncation mutants, however, hydrolyze Ac-CoA even in the absence of arylamine substrate, illustrating that the C-terminal undecapeptide controls hydrolysis of Ac-CoA by NAT from S. typhimurium.	Acetyl Coenzyme A	165-171	bromodomain containing 2	Homo sapiens	175-178	
9090119-1	1997	Arylalkylamine N-acetyltransferase (NAT; EC2.3.1.87) catalyzes N-acetylation of various arylalkylamines using acetyl-CoA as a donor substrate.	Acetyl Coenzyme A	110-120	bromodomain containing 2	Homo sapiens	36-39	
11239577-4	2001	The first three-dimensional structure of the unique NAT family shows the active-site cysteine to be aligned with conserved histidine and aspartate residues to form a catalytic triad, thus providing an activation mechanism for transfer of the acetyl group from acetyl CoA to cysteine.	Acetyl Coenzyme A	260-270	bromodomain containing 2	Homo sapiens	52-55	
11764764-8	2001	This is the first demonstration of acetyl CoA-arylamine NAT activity in human benign prostatic hyperplasia tissues.	Acetyl Coenzyme A	35-45	bromodomain containing 2	Homo sapiens	56-59	
10794727-9	2000	Selected NAT mutants exhibited K(m) values for acetyl-CoA that were comparable with those of the wild-type NATs, implying that the mutations affected acceptor substrate specificity rather than cofactor binding affinity.	Acetyl Coenzyme A	47-57	bromodomain containing 2	Homo sapiens	9-12	
34436463-3	2021	In human subjects, the serum concentrations of acetylated forms of taurine (NAT) and carnitine (ACT), which are the metabolites of acetyl-CoA buffering, significantly increased after a full marathon.	Acetyl Coenzyme A	131-141	bromodomain containing 2	Homo sapiens	76-79	
8182542-4	1994	Arylamine N-acetyltransferase (NAT) catalyzes the acetyl CoA-dependent N-acetylation of primary arylamine and hydrazine substrates such as sulfamethazine, isoniazid, p-aminobenzoic acid as well as arylamine carcinogens such as 2-aminofluorene and benzidine.	Acetyl Coenzyme A	50-60	bromodomain containing 2	Homo sapiens	31-34