PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34477360-3 2021 Interestingly, genetic deletion of N-acetyltransferase-8-like (NAT8L), which encodes aspartate N-aceyltransferase (ANAT), an enzyme responsible for the synthesis of NAA from l-aspartate and acetyl-CoA, leads to normalization of NAA levels and improvement of symptoms in several genetically engineered mouse models of CD. Acetyl Coenzyme A 190-200 N-acetyltransferase 8-like Mus musculus 35-61 34477360-3 2021 Interestingly, genetic deletion of N-acetyltransferase-8-like (NAT8L), which encodes aspartate N-aceyltransferase (ANAT), an enzyme responsible for the synthesis of NAA from l-aspartate and acetyl-CoA, leads to normalization of NAA levels and improvement of symptoms in several genetically engineered mouse models of CD. Acetyl Coenzyme A 190-200 N-acetyltransferase 8-like Mus musculus 63-68 31638418-1 2019 N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate. Acetyl Coenzyme A 91-108 N-acetyltransferase 8-like Mus musculus 42-71 31638418-1 2019 N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate. Acetyl Coenzyme A 91-108 N-acetyltransferase 8-like Mus musculus 79-84 26164607-3 2015 Shati/Nat8l produces N-acetylaspartate from aspartate and acetyl-CoA. Acetyl Coenzyme A 58-68 N-acetyltransferase 8-like Mus musculus 0-5 29203794-2 2017 Recently, it has been reported that SHATI is N-acetyltransferase 8-like protein (NAT8L) that produces N-acetylaspatate (NAA) from aspartate and acetyl-CoA. Acetyl Coenzyme A 144-154 N-acetyltransferase 8-like Mus musculus 36-41 29203794-2 2017 Recently, it has been reported that SHATI is N-acetyltransferase 8-like protein (NAT8L) that produces N-acetylaspatate (NAA) from aspartate and acetyl-CoA. Acetyl Coenzyme A 144-154 N-acetyltransferase 8-like Mus musculus 45-79 29203794-2 2017 Recently, it has been reported that SHATI is N-acetyltransferase 8-like protein (NAT8L) that produces N-acetylaspatate (NAA) from aspartate and acetyl-CoA. Acetyl Coenzyme A 144-154 N-acetyltransferase 8-like Mus musculus 81-86 26164607-3 2015 Shati/Nat8l produces N-acetylaspartate from aspartate and acetyl-CoA. Acetyl Coenzyme A 58-68 N-acetyltransferase 8-like Mus musculus 6-11 24155240-1 2013 NAT8L (N-acetyltransferase 8-like) catalyzes the formation of N-acetylaspartate (NAA) from acetyl-CoA and aspartate. Acetyl Coenzyme A 91-101 N-acetyltransferase 8-like Mus musculus 0-5 24155240-1 2013 NAT8L (N-acetyltransferase 8-like) catalyzes the formation of N-acetylaspartate (NAA) from acetyl-CoA and aspartate. Acetyl Coenzyme A 91-101 N-acetyltransferase 8-like Mus musculus 7-33 24155240-10 2013 Interestingly, the expression of ATP-citrate lyase is increased in Nat8l-silenced adipocytes and BAT of Nat8l-KO mice, indicating a compensatory mechanism to sustain the acetyl-CoA pool once Nat8l levels are reduced. Acetyl Coenzyme A 170-180 N-acetyltransferase 8-like Mus musculus 67-72 24155240-11 2013 Taken together, our data show that Nat8l impacts on the brown adipogenic phenotype and suggests the existence of the NAT8L-driven NAA metabolism as a novel pathway to provide cytosolic acetyl-CoA for lipid synthesis in adipocytes. Acetyl Coenzyme A 185-195 N-acetyltransferase 8-like Mus musculus 35-40 24155240-11 2013 Taken together, our data show that Nat8l impacts on the brown adipogenic phenotype and suggests the existence of the NAT8L-driven NAA metabolism as a novel pathway to provide cytosolic acetyl-CoA for lipid synthesis in adipocytes. Acetyl Coenzyme A 185-195 N-acetyltransferase 8-like Mus musculus 117-122