PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33064660-1 2020 Malic enzyme 1 (ME1) is a cytosolic protein that catalyzes the conversion of malate to pyruvate while concomitantly generating NADPH from NADP. Pyruvic Acid 87-95 2,4-dienoyl-CoA reductase 1 Homo sapiens 127-132 38020-7 1979 Use of NADPH minimizes interference from endogenous reactions such as that between lactate dehydrogenase and pyruvate. Pyruvic Acid 109-117 2,4-dienoyl-CoA reductase 1 Homo sapiens 7-12 32417402-6 2020 Validating these findings, deletion of the Mitochondrial Pyruvate Carrier-which is known to decrease TCA cycle activity and protect the liver from steatohepatitis-also diminished NADPH, elevated glutathione oxidation, and alleviated ER stress. Pyruvic Acid 57-65 2,4-dienoyl-CoA reductase 1 Homo sapiens 179-184