PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33166457-4 2020 Finally, the porin gene (por2) and the mitochondrial pyruvate carrier gene (MPC2) were knocked to impede mitochondrial transport of pyruvate, and the final modified strain alpha(L)-tCP-tAeDeltapor2 produced ethyl lactate 420.48 +- 6.03 mg/L. Pyruvic Acid 53-61 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 76-80 30979775-1 2019 The mitochondrial pyruvate carrier (MPC) is critical for cellular homeostasis, as it is required in central metabolism for transporting pyruvate from the cytosol into the mitochondrial matrix. Pyruvic Acid 18-26 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 36-39 27225475-0 2016 Improvement of isobutanol production in Saccharomyces cerevisiae by increasing mitochondrial import of pyruvate through mitochondrial pyruvate carrier. Pyruvic Acid 103-111 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 120-150 25672363-3 2015 The recently discovered mitochondrial pyruvate carrier (MPC), encoded by MPC1, MPC2, and MPC3 in yeast, is required for uptake of pyruvate into the organelle. Pyruvic Acid 38-46 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 56-59 25672363-3 2015 The recently discovered mitochondrial pyruvate carrier (MPC), encoded by MPC1, MPC2, and MPC3 in yeast, is required for uptake of pyruvate into the organelle. Pyruvic Acid 38-46 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 79-83 28357219-2 2014 In the latter case, the mitochondrial pyruvate carrier (MPC) is responsible for pyruvate transport into mitochondrial matrix space. Pyruvic Acid 38-46 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 56-59 22628554-4 2012 Members of the MPC family were found in the inner mitochondrial membrane, and yeast mutants lacking MPC proteins showed severe defects in mitochondrial pyruvate uptake. Pyruvic Acid 152-160 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 15-18 22628554-4 2012 Members of the MPC family were found in the inner mitochondrial membrane, and yeast mutants lacking MPC proteins showed severe defects in mitochondrial pyruvate uptake. Pyruvic Acid 152-160 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 100-103 22628558-2 2012 We have identified two proteins, Mpc1 and Mpc2, as essential for mitochondrial pyruvate transport in yeast, Drosophila, and humans. Pyruvic Acid 79-87 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 42-46 26748989-4 2016 The character of the molecular machinery that mediates pyruvate transport across mitochondrial membrane was elusive until the recent discovery of mitochondrial pyruvate carrier (MPC) in yeast and mammals. Pyruvic Acid 55-63 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 146-176 26748989-4 2016 The character of the molecular machinery that mediates pyruvate transport across mitochondrial membrane was elusive until the recent discovery of mitochondrial pyruvate carrier (MPC) in yeast and mammals. Pyruvic Acid 55-63 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 178-181 26748989-8 2016 Interestingly, MPC is expressed not only in procyclic trypanosomes with fully activated mitochondria but also in bloodstream trypanosomes in which most of pyruvate is excreted. Pyruvic Acid 155-163 mitochondrial pyruvate carrier Saccharomyces cerevisiae S288C 15-18