PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12935767-10 2003 The pyruvate-related redox manipulation inhibited the H2O2-induced p53 activation, restored the downregulated bcl-2 and the upregulated bax, and hence enhanced the bcl-2/bax expression ratio. Pyruvic Acid 4-12 BCL2 apoptosis regulator Homo sapiens 110-115 12935767-10 2003 The pyruvate-related redox manipulation inhibited the H2O2-induced p53 activation, restored the downregulated bcl-2 and the upregulated bax, and hence enhanced the bcl-2/bax expression ratio. Pyruvic Acid 4-12 BCL2 apoptosis regulator Homo sapiens 164-169 25014175-5 2014 Expression of Bcl-2Delta reduced lactate accumulation by redirecting the fate of intracellular pyruvate toward mitochondrial oxidation during the lactate-producing phase, and it significantly increased lactate re-uptake during the lactate-consuming phase. Pyruvic Acid 95-103 BCL2 apoptosis regulator Homo sapiens 14-19