PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21179242-4 2010 Retinal pigment epithelial (RPE) cells were shown to be sensitive to oxidative stress, and zinc, causing loss of nicotinamide adenine dinucleotide (NAD+) and adenine triphosphate (ATP), which was prevented by pyruvate and nicotinamide. Pyruvic Acid 209-217 ribulose-5-phosphate-3-epimerase Rattus norvegicus 28-31 21179242-17 2010 These results suggest that cyclic light maintenance, Zn(2+) chelation, pyruvate, and nicotinamide promote RPE and photoreceptor survival after injury and could be effective for various forms of retinal neurodegeneration. Pyruvic Acid 71-79 ribulose-5-phosphate-3-epimerase Rattus norvegicus 106-109