PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26405543-5 2015 In addition, the phosphorylated Cx43 (p-Cx43) level in the IR + IPOC group was lower than that in the IR + diazoxide group after 1-h reperfusion (26.1 vs. 29.4%, P>0.05); however, it was reversed after 3-h reperfusion and the p-Cx43 level in the IR + IPOC group was significantly higher than that in the IR + diazoxide group (32.8 vs. 18.7%, P<0.01). Diazoxide 312-321 gap junction protein, alpha 1 Rattus norvegicus 32-36 34769027-0 2021 Diazoxide Needs Mitochondrial Connexin43 to Exert Its Cytoprotective Effect in a Cellular Model of CoCl2-Induced Hypoxia. Diazoxide 0-9 gap junction protein, alpha 1 Rattus norvegicus 30-40 34769027-6 2021 In fact, our results demonstrate that in the presence of radicicol, an inhibitor of Cx43 translocation to mitochondria, the cytoprotective effects of diazoxide disappear. Diazoxide 150-159 gap junction protein, alpha 1 Rattus norvegicus 84-88 26405543-5 2015 In addition, the phosphorylated Cx43 (p-Cx43) level in the IR + IPOC group was lower than that in the IR + diazoxide group after 1-h reperfusion (26.1 vs. 29.4%, P>0.05); however, it was reversed after 3-h reperfusion and the p-Cx43 level in the IR + IPOC group was significantly higher than that in the IR + diazoxide group (32.8 vs. 18.7%, P<0.01). Diazoxide 312-321 gap junction protein, alpha 1 Rattus norvegicus 40-44 26405543-5 2015 In addition, the phosphorylated Cx43 (p-Cx43) level in the IR + IPOC group was lower than that in the IR + diazoxide group after 1-h reperfusion (26.1 vs. 29.4%, P>0.05); however, it was reversed after 3-h reperfusion and the p-Cx43 level in the IR + IPOC group was significantly higher than that in the IR + diazoxide group (32.8 vs. 18.7%, P<0.01). Diazoxide 312-321 gap junction protein, alpha 1 Rattus norvegicus 40-44 23418587-11 2013 The level of mitochondrial Connexin43, a gap junctional subunit, significantly increased by 70% in astrocytes after 10-min Diazoxide treatment. Diazoxide 123-132 gap junction protein, alpha 1 Rattus norvegicus 27-37 23418587-12 2013 Phospho-ERK signals were detected in Connexin43 immunoprecipitates in the Diazoxide-treated astrocytes, but not untreated control samples. Diazoxide 74-83 gap junction protein, alpha 1 Rattus norvegicus 37-47 16741159-1 2006 We have previously shown that connexin 43 (Cx43) is present in mitochondria, that its genetic depletion abolishes the protection of ischemia- and diazoxide-induced preconditioning, and that it is involved in reactive oxygen species (ROS) formation in response to diazoxide. Diazoxide 146-155 gap junction protein, alpha 1 Rattus norvegicus 30-41 19423616-6 2009 Ischaemic PC, diazoxide, and FGF-2 pre-ischaemic or post-ischaemic treatments elicited a P Cx43 state, defined as above-physiological levels of phospho-S262-Cx43 and phospho-S368-Cx43. Diazoxide 14-23 gap junction protein, alpha 1 Rattus norvegicus 91-95 19423616-6 2009 Ischaemic PC, diazoxide, and FGF-2 pre-ischaemic or post-ischaemic treatments elicited a P Cx43 state, defined as above-physiological levels of phospho-S262-Cx43 and phospho-S368-Cx43. Diazoxide 14-23 gap junction protein, alpha 1 Rattus norvegicus 157-161 19423616-6 2009 Ischaemic PC, diazoxide, and FGF-2 pre-ischaemic or post-ischaemic treatments elicited a P Cx43 state, defined as above-physiological levels of phospho-S262-Cx43 and phospho-S368-Cx43. Diazoxide 14-23 gap junction protein, alpha 1 Rattus norvegicus 157-161 17081390-7 2006 Phosphorylation of connexin43 was significantly increased, dephosphorylation and connexin43 intracellular redistribution significantly decreased (Cx43 size in the cellular membrane 1.00% +/- 0.35% and 0.83% +/- 0.31%, P < 0.001 vs. I/R: 0.19% +/- 0.06%) by IPC and diazoxide and these effects could be abolished by 5-hydroxydecanoic acid. Diazoxide 268-277 gap junction protein, alpha 1 Rattus norvegicus 81-91 16741159-1 2006 We have previously shown that connexin 43 (Cx43) is present in mitochondria, that its genetic depletion abolishes the protection of ischemia- and diazoxide-induced preconditioning, and that it is involved in reactive oxygen species (ROS) formation in response to diazoxide. Diazoxide 146-155 gap junction protein, alpha 1 Rattus norvegicus 43-47 16741159-1 2006 We have previously shown that connexin 43 (Cx43) is present in mitochondria, that its genetic depletion abolishes the protection of ischemia- and diazoxide-induced preconditioning, and that it is involved in reactive oxygen species (ROS) formation in response to diazoxide. Diazoxide 263-272 gap junction protein, alpha 1 Rattus norvegicus 30-41 16741159-1 2006 We have previously shown that connexin 43 (Cx43) is present in mitochondria, that its genetic depletion abolishes the protection of ischemia- and diazoxide-induced preconditioning, and that it is involved in reactive oxygen species (ROS) formation in response to diazoxide. Diazoxide 263-272 gap junction protein, alpha 1 Rattus norvegicus 43-47 16741159-7 2006 These results demonstrate that Cx43 is transported to the inner mitochondrial membrane through translocation via the TOM complex and that a normal mitochondrial Cx43 content is important for the diazoxide-related pathway of preconditioning. Diazoxide 195-204 gap junction protein, alpha 1 Rattus norvegicus 31-35 16741159-7 2006 These results demonstrate that Cx43 is transported to the inner mitochondrial membrane through translocation via the TOM complex and that a normal mitochondrial Cx43 content is important for the diazoxide-related pathway of preconditioning. Diazoxide 195-204 gap junction protein, alpha 1 Rattus norvegicus 161-165