PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21620734-0 2011 Heat shock protein 90 mediates anti-apoptotic effect of diazoxide by preventing the cleavage of Bid in hypothermic preservation rat hearts. Diazoxide 56-65 BH3 interacting domain death agonist Rattus norvegicus 96-99 21620734-9 2011 The cleavage of Bid increased after 9 hours of hypothermic preservation, which was inhibited by Celsior solution supplemented with diazoxide. Diazoxide 131-140 BH3 interacting domain death agonist Rattus norvegicus 16-19 21620734-11 2011 The Hsp90 inhibitor 17-allylamino-17-demethoxy-geldanamycin inhibited the diazoxide-induced decrease in cleavage of Bid, improvement of cardiac function, and decrease of apoptosis. Diazoxide 74-83 BH3 interacting domain death agonist Rattus norvegicus 116-119 21620734-13 2011 CONCLUSION: Hsp90 might mediate diazoxide-induced cardioprotection against apoptosis in hypothermic preservation heart by preventing the cleavage of Bid. Diazoxide 32-41 BH3 interacting domain death agonist Rattus norvegicus 149-152