PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17301957-4 2007 Here, we demonstrated for the first time that Kir 6.1, Kir 6.2 and SUR2 subunits of K(ATP) channels are functionally expressed in HaCaT cells and both non-selective K(ATP) channel opener pinacidil and mitoK(ATP) (mitochondrial K(ATP)) channel opener diazoxide attenuated UV-induced keratinocytes cell death. Diazoxide 250-259 ATP binding cassette subfamily C member 9 Homo sapiens 67-71 27161588-2 2016 Small-molecule inhibitors (e.g., sulfonylurea drugs) or activators (e.g., diazoxide) acting on SUR1 or SUR2 have been used clinically for decades to manage the inappropriate secretion of insulin in patients with Type 2 diabetes, hyperinsulinism and intractable hypertension. Diazoxide 74-83 ATP binding cassette subfamily C member 9 Homo sapiens 103-107 24037327-8 2013 However, the SUR2A-55 KATP were 70-fold less sensitive to block by ATP, and twice as resistant to intracellular Ca (2+) inhibition compared with the SUR2A KATP, and were markedly insensitive to KATP drugs, pinacidil, diazoxide, and glybenclamide. Diazoxide 217-226 ATP binding cassette subfamily C member 9 Homo sapiens 13-21 10625598-7 2000 The SUR2 segment containing the 12th through 17th predicted transmembrane domains, TMD12-17, confers sensitivity to the benzopyran, cromakalim, and the pyridine, pinacidil, whereas an SUR1 segment which includes TMD6-11 and the first nucleotide-binding fold, NBF1, controls responsiveness to the benzothiadiazine, diazoxide. Diazoxide 314-323 ATP binding cassette subfamily C member 9 Homo sapiens 4-8