PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15699441-5	2005	Stimulation of RVSMCs by Ang II or diazoxide increased phosphorylated MAP kinases (ERK1/2, p38, and JNK), as well as superoxide production, which were then suppressed by 5-HD pretreatment in a dose-dependent manner, except for ERK1/2 activation by Ang II.	Diazoxide	35-44	angiotensinogen	Rattus norvegicus	248-254	
19460779-7	2009	In patch-clamp experiments, cardiomyocytes cultured with Ang II or TNFalpha exhibited responsiveness to diazoxide, in terms of both K(ATP) current and action potential shortening.	Diazoxide	104-113	angiotensinogen	Rattus norvegicus	57-63	
15699441-7	2005	Ang II-like diazoxide depolarized the mitochondrial membrane potential (DeltaPsi(M)) of RVSMCs determined by JC-1 fluorescence, which was inhibited by 5-HD.	Diazoxide	12-21	angiotensinogen	Rattus norvegicus	0-6	
15699441-9	2005	These results reveal that Ang II stimulates mitochondrial ROS production through the opening of mitoK(ATP) channels in the vasculature-like diazoxide, leading to reduction of DeltaPsi(M) and redox-sensitive activation of MAP kinase; however, generated ROS from mitochondria do not contribute to Ang II-induced vasoconstriction.	Diazoxide	140-149	angiotensinogen	Rattus norvegicus	26-32	
15699441-9	2005	These results reveal that Ang II stimulates mitochondrial ROS production through the opening of mitoK(ATP) channels in the vasculature-like diazoxide, leading to reduction of DeltaPsi(M) and redox-sensitive activation of MAP kinase; however, generated ROS from mitochondria do not contribute to Ang II-induced vasoconstriction.	Diazoxide	140-149	angiotensinogen	Rattus norvegicus	295-301	
11124154-5	2001	min(-1) ANG II, attenuation of the induced increases in arterial pressure with the arteriolar vasodilator diazoxide resulted in greater water intakes and shorter latencies to drink.	Diazoxide	106-115	angiotensinogen	Rattus norvegicus	8-14	
10938248-5	2000	Furthermore, a highly significant correlation was observed when plasma ANG II levels were plotted as a function of plasma renin activity after intravenous infusion of renin and after diazoxide and isoproterenol treatments.	Diazoxide	183-192	angiotensinogen	Rattus norvegicus	71-77	
989773-6	1976	When diazoxide was injected with the renin extract into hypoxic nephrectomized rats, the vasopressor effect of renin was abolished for 4 hours, and the plasma Ep levels were significantly lower than those of hypoxic nephrectomized animals injected only with renin, Injection of angiotensin II into anephric, hypoxic rats had an effect comparable to that of renin on extrarenal Ep roduction.	Diazoxide	5-14	angiotensinogen	Rattus norvegicus	278-292	
17000-2	1977	The hypotensive activity of diazoxide was unimpaired after ganglion blockade with pentolinium or alpha adrenoreceptor blockade with phentolamine; diazoxide also significantly attenuated angiotensin II pressor responses.	Diazoxide	146-155	angiotensinogen	Rattus norvegicus	186-200	
901072-3	1977	Hydralzaine and diazoxide also attenuated angiotensin II pressor responses.	Diazoxide	16-25	angiotensinogen	Rattus norvegicus	42-56